- Pancreatic beta-Cell Neogenesis by Direct Conversion from Mature alpha-Cells
[作者:Chung, CH; Hao, EG; Piran, R; Keinan, E; Levine, F,期刊:Stem Cells, 页码:1630-1638 , 文章类型: Article,,卷期:2010年28-9]
- Because type 1 and type 2 diabetes are characterized by loss of beta-cells, beta-cell regeneration has garnered great interest as an approach to diabetes therapy. Here, we developed a new model of beta-cell regeneration,...
- Fibroblast Growth Factor Type 2 Signaling Is Critical for DNA Repair in Human Keratinocyte Stem Cells
[作者:Harfouche, G; Vaigot, P; Rachidi, W; Rigaud, O; Moratille, S; Marie, M; Lemaitre, G; Fortunel, NO; Martin, MT,期刊:Stem Cells, 页码:1639-1648 , 文章类型: Article,,卷期:2010年28-9]
- Tissue stem cells must be endowed with superior maintenance and repair systems to ensure genomic stability over multiple generations, which would be less necessary in more differentiated cells. We previously reported tha...
- FRS2 alpha Regulates Erk Levels to Control a Self-Renewal Target Hes1 and Proliferation of FGF-Responsive Neural Stem/Progenitor Cells
[作者:Sato, T; Shimazaki, T; Naka, H; Fukami, SI; Satoh, Y; Okano, H; Lax, I; Schlessinger, J; Gotoh, N,期刊:Stem Cells, 页码:1660-1672 , 文章类型: Article,,卷期:2010年28-9]
- Fibroblast growth factor (FGF) is among the most common growth factors used in cultures to maintain self-renewal and proliferative capabilities of a variety of stem cells, including neural stem cells (NSCs). However, the...
- Notch Activation Differentially Regulates Renal Progenitors Proliferation and Differentiation Toward the Podocyte Lineage in Glomerular Disorders
[作者:Lasagni, L; Ballerini, L; Angelotti, ML; Parente, E; Sagrinati, C; Mazzinghi, B; Peired, A; Ronconi, E; Becherucci, F; Bani, D; Gacci, M; Carini, M; Lazzeri, E; Romagnani, P,期刊:Stem Cells, 页码:1673-1685 , 文章类型: Article,,卷期:2010年28-9]
- Glomerular diseases account for 90% of end-stage kidney disease. Podocyte loss is a common determining factor for the progression toward glomerulosclerosis. Mature podocytes cannot proliferate, but recent evidence sugges...
- STEM CELLS' Position Statement on hESC Research
[作者:Stojkovic, M; Pittenger, MF; Nolta, JA; Lako, M; Lappin, TRJ; Murphy, MJ,期刊:Stem Cells, 页码:1456-1456 , 文章类型: Editorial Material,,卷期:2010年28-9]
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- Human Induced Pluripotent Stem Cells Develop Teratoma More Efficiently and Faster Than Human Embryonic Stem Cells Regardless the Site of Injection
[作者:Gutierrez-Aranda, I; Ramos-Mejia, V; Bueno, C; Munoz-Lopez, M; Real, PJ; Macia, A; Sanchez, L; Ligero, G; Garcia-Parez, JL; Menendez, P,期刊:Stem Cells, 页码:1568-1570 , 文章类型: Letter,,卷期:2010年28-9]
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- Concise Review: Polarity in Stem Cells, Disease, and Aging
[作者:Florian, MC; Geiger, H,期刊:Stem Cells, 页码:1623-1629 , 文章类型: Review,,卷期:2010年28-9]
- Adult somatic stem cells are central to homeostasis in tissues that present with a high cellular turnover like the skin, intestine, and the hematopoietic system. It is thought that polarity is particularly important with...
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