- Adoptive transfer of pp65-specific T cells for the treatment of chemorefractory cytomegalovirus disease or reactivation after haploidentical and matched unrelated stem cell transplantation
[作者：Feuchtinger, T; Opherk, K; Bethge, WA; Topp, MS; Schuster, FR; Weissinger, EM; Mohty, M; Or, R; Maschan, M; Schumm, M; Hamprecht, K; Handgretinger, R; Lang, P; Einsele, H,期刊：Blood, 页码：4360-4367 , 文章类型： Article，,卷期：2010年116-20]
- Cytomegalovirus (CMV) disease and infection refractory to antiviral treatment after allogeneic stem cell transplantation (allo-SCT) is associated with a high mortality. Adoptive transfer of CMV-specific T cells could rec...
- American Society of Hematology/American Society of Clinical Oncology clinical practice guideline update on the use of epoetin and darbepoetin in adult patients with cancer
[作者：Rizzo, JD; Brouwers, M; Hurley, P; Seidenfeld, J; Arcasoy, MO; Spivak, JL; Bennett, CL; Bohlius, J; Evanchuk, D; Goode, MJ; Jakubowski, AA; Regan, DH; Somerfield, MR,期刊：Blood, 页码：4045-4059 , 文章类型： Review，,卷期：2010年116-20]
- To update American Society of Hematology/American Society of Clinical Oncology recommendations for use of erythropoiesis-stimulating agents (ESAs) in patients with cancer. Methods: An Update Committee reviewed data publi...
- Allogeneic stem cell transplantation for adult Philadelphia chromosome-negative acute lymphocytic leukemia: comparable survival rates but different risk factors between related and unrelated transplantation in first complete remission
[作者：Nishiwaki, S; Inamoto, Y; Sakamaki, H; Kurokawa, M; Iida, H; Ogawa, H; Fukuda, T; Ozawa, Y; Kobayashi, N; Kasai, M; Mori, T; Iwato, K; Yoshida, T; Onizuka, M; Kawa, K; Morishima, Y; Suzuki, R; Atsuta, Y; Miyamura, K,期刊：Blood, 页码：4368-4375 , 文章类型： Article，,卷期：2010年116-20]
- To identify factors to improve the outcomes of related and unrelated allogeneic stem cell transplantations (allo-SCT) for Philadelphia chromosome-negative acute lymphocytic leukemia (Ph- ALL) in the first complete remiss...
- Podoplanin-Fc reduces lymphatic vessel formation in vitro and in vivo and causes disseminated intravascular coagulation when transgenically expressed in the skin
[作者：Cueni, LN; Chen, L; Zhang, H; Marino, D; Huggenberger, R; Alitalo, A; Bianchi, R; Detmar, M,期刊：Blood, 页码：4376-4384 , 文章类型： Article，,卷期：2010年116-20]
- Podoplanin is a small transmembrane protein required for development and function of the lymphatic vascular system. To investigate the effects of interfering with its function, we produced an Fc fusion protein of its ect...
- Rationale and efficacy of interleukin-1 targeting in Erdheim-Chester disease
[作者：Aouba, A; Georgin-Lavialle, S; Pagnoux, C; Silva, NM; Renand, A; Galateau-Salle, F; Le Toquin, S; Bensadoun, H; Larousserie, F; Silvera, S; Provost, N; Candon, S; Seror, R; de Menthon, M; Hermine, O; Guillevin, L; Bienvenu, B,期刊：Blood, 页码：4070-4076 , 文章类型： Article，,卷期：2010年116-20]
- Erdheim-Chester disease (ECD) pathophysiology remains largely unknown. Its treatment is not codified and usually disappointing. Interferon (IFN)-alpha therapy lacks efficacy for some life-threatening manifestations and h...
- Zosuquidar, a novel modulator of P-glycoprotein, does not improve the outcome of older patients with newly diagnosed acute myeloid leukemia: a randomized, placebo-controlled trial of the Eastern Cooperative Oncology Group 3999
[作者：Cripe, LD; Uno, H; Paietta, EM; Litzow, MR; Ketterling, RP; Bennett, JM; Rowe, JM; Lazarus, HM; Luger, S; Tallman, MS,期刊：Blood, 页码：4077-4085 , 文章类型： Article，,卷期：2010年116-20]
- Zosuquidar, which modulates P-glycoprotein (P-gp) with minimal delay of anthracycline clearance, may reverse P-gp-mediated resistance in acute myeloid leukemia without increased toxicity. A total of 449 adults older than...
- Distinct clinical and biological features of de novo acute myeloid leukemia with additional sex comb-like 1 (ASXL1) mutations
[作者：Chou, WC; Huang, HH; Hou, HA; Chen, CY; Tang, JL; Yao, M; Tsay, W; Ko, BS; Wu, SJ; Huang, SY; Hsu, SC; Chen, YC; Huang, YN; Chang, YC; Lee, FY; Liu, MC; Liu, CW; Tseng, MH; Huang, CF; Tien, HF,期刊：Blood, 页码：4086-4094 , 文章类型： Article，,卷期：2010年116-20]
- Mutations in the additional sex comb-like 1 (ASXL1) gene were recently shown in various myeloid malignancies, but they have not been comprehensively investigated in acute myeloid leukemia (AML). In this study, we analyze...
- Improvement in hematological, visceral, and skeletal manifestations of Gaucher disease type 1 with oral eliglustat tartrate (Genz-112638) treatment: 2-year results of a phase 2 study
[作者：Lukina, E; Watman, N; Arreguin, EA; Dragosky, M; Iastrebner, M; Rosenbaum, H; Phillips, M; Pastores, GM; Kamath, RS; Rosenthal, DI; Kaper, M; Singh, T; Puga, AC; Peterschmitt, MJ,期刊：Blood, 页码：4095-4098 , 文章类型： Article，,卷期：2010年116-20]
- Eliglustat tartrate is an investigational oral substrate reduction therapy for Gaucher disease type 1 that is pharmacologically distinct from intravenous enzyme replacement therapy. Eliglustat tartrate improved clinical ...
- Eradication of B-lineage cells and regression of lymphoma in a patient treated with autologous T cells genetically engineered to recognize CD19
[作者：Kochenderfer, JN; Wilson, WH; Janik, JE; Dudley, ME; Stetler-Stevenson, M; Feldman, SA; Maric, I; Raffeld, M; Nathan, DAN; Lanier, BJ; Morgan, RA; Rosenberg, SA,期刊：Blood, 页码：4099-4102 , 文章类型： Article，,卷期：2010年116-20]
- Adoptive transfer of genetically modified T cells is an attractive approach for generating antitumor immune responses. We treated a patient with advanced follicular lymphoma by administering a preparative chemotherapy re...
- Essential role for focal adhesion kinase in regulating stress hematopoiesis
[作者：Vemula, S; Ramdas, B; Hanneman, P; Martin, J; Beggs, HE; Kapur, R,期刊：Blood, 页码：4103-4115 , 文章类型： Article，,卷期：2010年116-20]
- Focal adhesion kinase (FAK) is a nonreceptor tyrosine kinase that has been extensively studied in fibroblasts; however its function in hematopoiesis remains an enigma. FAK is thought to be expressed in myeloid and erythr...
- Lineage-instructive function of C/EBP alpha in multipotent hematopoietic cells and early thymic progenitors
[作者：Wolfler, A; Oorschot, AADV; Haanstra, JR; Valkhof, M; Bodner, C; Vroegindeweij, E; van Strien, P; Novak, A; Cupedo, T; Touw, IP,期刊：Blood, 页码：4116-4125 , 文章类型： Article，,卷期：2010年116-20]
- Hematopoiesis is tightly controlled by transcription regulatory networks, but how and when specific transcription factors control lineage commitment are still largely unknown. Within the hematopoietic stem cell (Lin(-)Sc...
- The atypical chemokine receptor CCX-CKR scavenges homeostatic chemokines in circulation and tissues and suppresses Th17 responses
[作者：Comerford, I; Nibbs, RJB; Litchfield, W; Bunting, M; Harata-Lee, Y; Haylock-Jacobs, S; Forrow, S; Korner, H; McColl, SR,期刊：Blood, 页码：4130-4140 , 文章类型： Article，,卷期：2010年116-20]
- Our previous in vitro studies led to proposals that the atypical chemokine receptor CCX-CKR is a scavenger of CCR7 ligand homeostatic chemokines. In the present study, we generated CCX-CKR-/- mice and confirm this scaven...
- IgA-mediated human autoimmune hemolytic anemia as a result of hemagglutination in the spleen, but independent of complement activation and Fc alpha RI
[作者：Chadebech, P; Michel, M; Janvier, D; Yamada, K; Copie-Bergman, C; Bodivit, G; Bensussan, A; Fournie, JJ; Godeau, B; Bierling, P; Izui, S; Noizat-Pirenne, F,期刊：Blood, 页码：4141-4147 , 文章类型： Article，,卷期：2010年116-20]
- Autoimmune hemolytic anemia (AIHA) due to warm-acting IgA autoantibodies is rare. We explored the pathogenic mechanisms underlying destruction of red blood cells (RBCs) in a patient with severe AIHA mediated exclusively ...
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