- Targeted methylation of CMV and E1A viral promoters
[作者:Hsu, CC; Li, HP; Hung, YH; Leu, YW; Wu, WH; Wang, FS; Lee, KD; Chang, PJ; Wu, CS; Lu, YJ; Huang, THM; Chang, YS; Hsiao, SH,期刊:Biochemical and Biophysical Research Communications, 页码:228-234 , 文章类型: Article,,卷期:2010年402-2]
- DNA methylation is a gene-silencing and host defense system that can down-regulate viral gene expression in mammalian cells. An established targeted DNA methylation method was used to demonstrate that genome-integrated C...
- Endoplasmic reticulum stress increases the expression and function of toll-like receptor-2 in epithelial cells
[作者:Shimasaki, S; Koga, T; Shuto, T; Suico, MA; Sato, T; Watanabe, K; Morino-Koga, S; Taura, M; Okada, S; Mori, K; Kai, H,期刊:Biochemical and Biophysical Research Communications, 页码:235-240 , 文章类型: Article,,卷期:2010年402-2]
- Endoplasmic reticulum (ER) stress is involved in a wide range of pathological conditions including neurodegenerative disorders, diabetes mellitus, atherosclerosis, inflammation, and infection. The ability of ER stress to...
- Soluble factors from IL-1 beta-stimulated astrocytes activate NR1a/NR2B receptors: Implications for HIV-1-induced neurodegeneration
[作者:Jing, T; Wu, L; Borgmann, K; Surendran, S; Ghorpade, A; Liu, JU; Xiong, HG,期刊:Biochemical and Biophysical Research Communications, 页码:241-246 , 文章类型: Article,,卷期:2010年402-2]
- Astrocytes play an important role in astrocyte-neuron homeostasis. In HIV-1-infected brain, interleukin 1 beta (IL-1 beta) activation of astrocytes contributes to neurodegeneration. However, the molecular mechanisms unde...
- Oleate and eicosapentaenoic acid attenuate palmitate-induced inflammation and apoptosis in renal proximal tubular cell
[作者:Soumura, M; Kume, S; Isshiki, K; Takeda, N; Araki, S; Tanaka, Y; Sugimoto, T; Chin-Kanasaki, M; Nishio, Y; Haneda, M; Koya, D; Kashiwagi, A; Maegawa, H; Uzu, T,期刊:Biochemical and Biophysical Research Communications, 页码:265-271 , 文章类型: Article,,卷期:2010年402-2]
- Free fatty acid (FFA)-bound albumin, which is filtrated through the glomeruli and reabsorbed into proximal tubular cells, is one of the crucial mediators of tubular damage in proteinuric kidney disease. In this study, we...
- Overexpression of phosphoinositide-3-kinase class II alpha enhances mesenchymal stem cell survival in infarcted myocardium
[作者:Eun, LY; Song, BW; Cha, MJ; Song, H; Kim, IK; Choi, E; Chang, W; Lim, S; Choi, EJ; Ham, O; Lee, SY; Byun, KH; Jang, Y; Hwang, KC,期刊:Biochemical and Biophysical Research Communications, 页码:272-279 , 文章类型: Article,,卷期:2010年402-2]
- The efficacy of mesenchymal stem cell (MSC) therapy for myocardial regeneration is limited by the poor survival of stem cells after transplantation into the infarcted heart. To improve the cell survival of MSCs in the in...
- Novel GPR119 agonist AS1535907 contributes to first-phase insulin secretion in rat perfused pancreas and diabetic db/db mice
[作者:Yoshida, S; Ohishi, T; Matsui, T; Tanaka, H; Oshima, H; Yonetoku, Y; Shibasaki, M,期刊:Biochemical and Biophysical Research Communications, 页码:280-285 , 文章类型: Article,,卷期:2010年402-2]
- G protein-coupled receptor (GPR) 119 is highly expressed in pancreatic p-cells and enhances the effect of glucose-stimulated insulin secretion (GSIS) on activation. The development of an oral GPR119 agonist that specific...
- Identification of miR-1 as a micro RNA that supports late-stage differentiation of growth cartilage cells
[作者:Sumiyoshi, K; Kubota, S; Ohgawara, T; Kawata, K; Nishida, T; Shimo, T; Yamashiro, T; Takigawa, M,期刊:Biochemical and Biophysical Research Communications, 页码:286-290 , 文章类型: Article,,卷期:2010年402-2]
- The process of endochondral ossification is strictly regulated by a variety of extracellular and intracellular factors. Recently, it has become recognized that specific miRNAs are involved in this process by regulating t...
- IDH1 and IDH2 mutations are frequent in Chinese patients with acute myeloid leukemia but rare in other types of hematological disorders
[作者:Zou, Y; Zeng, Y; Zhang, DF; Zou, SH; Cheng, YF; Yao, YG,期刊:Biochemical and Biophysical Research Communications, 页码:378-383 , 文章类型: Article,,卷期:2010年402-2]
- Frequent mutations in the isocitrate dehydrogenase 1 and 2 genes (IDH1 and IDH2) have been identified in gliomas and acute myeloid leukemia (AML). Our aim is to assess whether IDH mutations were presented in Chinese pati...
- Novel role of specific Tudor domains in Tudor-Aubergine protein complex assembly and distribution during Drosophila oogenesis
[作者:Creed, TM; Loganathan, SN; Varonin, D; Jackson, CA; Arkov, AL,期刊:Biochemical and Biophysical Research Communications, 页码:384-389 , 文章类型: Article,,卷期:2010年402-2]
- Germ cells give rise to the next generation and contain ribonucleoprotein particles, germ granules. In these granules, Piwi protein Aubergine has been shown to interact with Tudor protein in Drosophila. Tudor protein has...
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