- Herpes Simplex Virus Immediate-Early ICP0 Protein Inhibits Toll-Like Receptor 2-Dependent Inflammatory Responses and NF-kappa B Signaling
[作者:van Lint, AL; Murawski, MR; Goodbody, RE; Severa, M; Fitzgerald, KA; Finberg, RW; Knipe, DM; Kurt-Jones, EA,期刊:Journal of virology, 页码:10802-10811 , 文章类型: Article,,卷期:2010年84-20]
- The discovery of the Toll-like receptors (TLRs) and their importance in the regulation of host responses to infection raised attention to the complex interplay between viral gene products and the host innate immune respo...
- Genetic Analyses of HIV-1 env Sequences Demonstrate Limited Compartmentalization in Breast Milk and Suggest Viral Replication within the Breast That Increases with Mastitis
[作者:Gantt, S; Carlsson, J; Heath, L; Bull, ME; Shetty, AK; Mutsvangwa, J; Musingwini, G; Woelk, G; Zijenah, LS; Katzenstein, DA; Mullins, JI; Frenkel, LM,期刊:Journal of virology, 页码:10812-10819 , 文章类型: Article,,卷期:2010年84-20]
- The concentration of human immunodeficiency virus type 1 (HIV-1) is generally lower in breast milk than in blood. Mastitis, or inflammation of the breast, is associated with increased levels of milk HIV-1 and risk of mot...
- Rearranged JC Virus Noncoding Control Regions Found in Progressive Multifocal Leukoencephalopathy Patient Samples Increase Virus Early Gene Expression and Replication Rate
[作者:Gosert, R; Kardas, P; Major, EO; Hirsch, HH,期刊:Journal of virology, 页码:10448-10456 , 文章类型: Article,,卷期:2010年84-20]
- Polyomavirus JC (JCV) infects similar to 60% of the general population, followed by asymptomatic urinary shedding in similar to 20%. In patients with pronounced immunodeficiency, including HIV/AIDS, JCV can cause progres...
- Gag-Protease-Mediated Replication Capacity in HIV-1 Subtype C Chronic Infection: Associations with HLA Type and Clinical Parameters
[作者:Wright, JK; Brumme, ZL; Carlson, JM; Heckerman, D; Kadie, CM; Brumme, CJ; Wang, BX; Losina, E; Miura, T; Chonco, F; van der Stok, M; Mncube, Z; Bishop, K; Goulder, PJR; Walker, BD; Brockman, MA; Ndung'u, T,期刊:Journal of virology, 页码:10820-10831 , 文章类型: Article,,卷期:2010年84-20]
- The mechanisms underlying HIV-1 control by protective HLA class I alleles are not fully understood and could involve selection of escape mutations in functionally important Gag epitopes resulting in fitness costs. This s...
- Inactivation and Disassembly of the Anaphase-Promoting Complex during Human Cytomegalovirus Infection Is Associated with Degradation of the APC5 and APC4 Subunits and Does Not Require UL97-Mediated Phosphorylation of Cdh1
[作者:Tran, K; Kamil, JP; Coen, DM; Spector, DH,期刊:Journal of virology, 页码:10832-10843 , 文章类型: Article,,卷期:2010年84-20]
- Infection of quiescent cells by human cytomegalovirus (HCMV) elicits severe cell cycle deregulation, resulting in a G(1)/S arrest, which can be partly attributed to the inactivation of the anaphase-promoting complex (APC...
- A gC1qR Prevents White Spot Syndrome Virus Replication in the Freshwater Crayfish Pacifastacus leniusculus
[作者:Watthanasurorot, A; Jiravanichpaisal, P; Soderhall, I; Soderhall, K,期刊:Journal of virology, 页码:10844-10851 , 文章类型: Article,,卷期:2010年84-20]
- The gC1qR/p32 protein is a multiple receptor for several proteins and pathogens. We cloned a gC1qR homologue in a crustacean, Pacifastacus leniusculus, and analyzed the expression of P. leniusculus C1qR (PlgC1qR) in vari...
- Convergence of Kaposi's Sarcoma-Associated Herpesvirus Reactivation with Epstein-Barr Virus Latency and Cellular Growth Mediated by the Notch Signaling Pathway in Coinfected Cells
[作者:Spadavecchia, S; Gonzalez-Lopez, O; Carroll, KD; Palmeri, D; Lukac, DM,期刊:Journal of virology, 页码:10488-10500 , 文章类型: Article,,卷期:2010年84-20]
- Kaposi's sarcoma-associated herpesvirus (KSHV) is the etiologic agent of primary effusion lymphoma (PEL). All PEL cell lines are infected with KSHV, and 70% are coinfected with Epstein-Barr virus (EBV). KSHV reactivation...
- Epitope-Specific Regulatory CD4 T Cells Reduce Virus-Induced Illness while Preserving CD8 T-Cell Effector Function at the Site of Infection
[作者:Liu, J; Ruckwardt, TJ; Chen, M; Nicewonger, JD; Johnson, TR; Graham, BS,期刊:Journal of virology, 页码:10501-10509 , 文章类型: Article,,卷期:2010年84-20]
- The role of epitope-specific regulatory CD4 T cells in modulating CD8 T-cell-mediated immunopathology during acute viral infection has not been well defined. In the murine model of respiratory syncytial virus (RSV) infec...
- A Maraviroc-Resistant HIV-1 with Narrow Cross-Resistance to Other CCR5 Antagonists Depends on both N-Terminal and Extracellular Loop Domains of Drug-Bound CCR5
[作者:Tilton, JC; Wilen, CB; Didigu, CA; Sinha, R; Harrison, JE; Agrawal-Gamse, C; Henning, EA; Bushman, FD; Martin, JN; Deeks, SG; Doms, RW,期刊:Journal of virology, 页码:10863-10876 , 文章类型: Article,,卷期:2010年84-20]
- CCR5 antagonists inhibit HIV entry by binding to a coreceptor and inducing changes in the extracellular loops (ECLs) of CCR5. In this study, we analyzed viruses from 11 treatment-experienced patients who experienced viro...
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