个性化文献订阅>文章检索

文章名     作者     期刊名     摘要     卷     期         如果没有找到您所需要的文献，请点击 ——此处申请     共66条记录   Mammalian Telomeric DNA Suppresses Endotoxin-induced Uveitis [作者：Yagci, FC; Aslan, O; Gursel, M; Tincer, G; Ozdamar, Y; Karatepe, K; Akcali, KC; Gursel, I,期刊：Journal of Biological Chemistry, 页码：28806-28811 , 文章类型： Article，,卷期：2010年285-37] Telomeric regions of mammalian chromosomes contain suppressive TTAGGG motifs that inhibit several proinflammatory and Th1-biased immune responses. Synthetic oligodeoxynucleotides (ODN) expressing suppressive motifs can r... Specific Inhibition of NEIL-initiated Repair of Oxidized Base Damage in Human Genome by Copper and Iron POTENTIAL ETIOLOGICAL LINKAGE TO NEURODEGENERATIVE DISEASES [作者：Hegde, ML; Hegde, PM; Holthauzen, LMF; Hazra, TK; Rao, KSJ; Mitra, S,期刊：Journal of Biological Chemistry, 页码：28812-28825 , 文章类型： Article，,卷期：2010年285-37] Dyshomeostasis of transition metals iron and copper as well as accumulation of oxidative DNA damage have been implicated in multitude of human neurodegenerative diseases, including Alzheimer disease and Parkinson disease... The Identification of Histidine 712 as a Critical Residue for Constitutive TRPV5 Internalization [作者：de Groot, T; Verkaart, S; Xi, Q; Bindels, RJM; Hoenderop, JGJ,期刊：Journal of Biological Chemistry, 页码：28481-28487 , 文章类型： Article，,卷期：2010年285-37] The epithelial Ca2+ channel TRPV5 constitutes the apical entry gate for Ca2+ transport in renal epithelial cells. Ablation of the trpv5 gene in mice leads to a reduced Ca2+ reabsorption. TRPV5 is tightly regulated by var... Role of the Residues of the 39-Loop in Determining the Substrate and Inhibitor Specificity of Factor IXa [作者：Yang, LK; Manithody, C; Qureshi, SH; Rezaie, AR,期刊：Journal of Biological Chemistry, 页码：28488-28495 , 文章类型： Article，,卷期：2010年285-37] The activation of antithrombin (AT) by heparin facilitates the exosite-dependent interaction of the serpin with factors IXa (FIXa) and Xa (FXa), thereby improving the rate of reactions by 300- to 500-fold. Relative to FX... Components of the Secondary Pathway Stimulate the Primary Pathway of Eukaryotic Okazaki Fragment Processing [作者：Henry, RA; Balakrishnan, L; Ying-Lin, ST; Campbell, JL; Bambara, RA,期刊：Journal of Biological Chemistry, 页码：28496-28505 , 文章类型： Article，,卷期：2010年285-37] Reconstitution of eukaryotic Okazaki fragment processing implicates both one- and two-nuclease pathways for processing flap intermediates. In most cases, FEN1 (flap endonuclease 1) is able to efficiently cleave short fla... Translational Repression by Deadenylases [作者：Cooke, A; Prigge, A; Wickens, M,期刊：Journal of Biological Chemistry, 页码：28506-28513 , 文章类型： Article，,卷期：2010年285-37] The CCR4-CAF1-NOT complex is a major cytoplasmic deadenylation complex in yeast and mammals. This complex associates with RNA-binding proteins and microRNAs to repress translation of target mRNAs. We sought to determine ... Complementary Roles for Exonuclease 1 and Flap Endonuclease 1 in Maintenance of Triplet Repeats [作者：Vallur, AC; Maizels, N,期刊：Journal of Biological Chemistry, 页码：28514-28519 , 文章类型： Article，,卷期：2010年285-37] Trinucleotide repeats can form stable secondary structures that promote genomic instability. To determine how such structures are resolved, we have defined biochemical activities of the related RAD2 family nucleases, FEN... Deficiency of Chemokine Receptor CCR1 Causes Osteopenia Due to Impaired Functions of Osteoclasts and Osteoblasts [作者：Hoshino, A; Iimura, T; Ueha, S; Hanada, S; Maruoka, Y; Mayahara, M; Suzuki, K; Imai, T; Ito, M; Manome, Y; Yasuhara, M; Kirino, T; Yamaguchi, A; Matsushima, K; Yamamoto, K,期刊：Journal of Biological Chemistry, 页码：28826-28837 , 文章类型： Article，,卷期：2010年285-37] Chemokines are characterized by the homing activity of leukocytes to targeted inflammation sites. Recent research indicates that chemokines play more divergent roles in various phases of pathogenesis as well as immune re... Dephosphorylation-dependent Inhibitory Activity of Juxtanodin on Filamentous Actin Disassembly [作者：Meng, J; Xia, WH; Tang, JH; Tang, BL; Liang, FY,期刊：Journal of Biological Chemistry, 页码：28838-28849 , 文章类型： Article，,卷期：2010年285-37] In the vertebrate central nervous system, maturation of oligodendrocytes is accompanied by a dramatic transformation of cell morphology. Juxtanodin (JN) is an actin cytoskeleton-related oligodendroglial protein that prom... Identification of Two Nuclear Factor of Activated T-cells (NFAT)-response Elements in the 5 '-Upstream Regulatory Region of the ET-1 Promoter [作者：Strait, KA; Stricklett, PK; Kohan, RM; Kohan, DE,期刊：Journal of Biological Chemistry, 页码：28520-28528 , 文章类型： Article，,卷期：2010年285-37] Collecting duct-derived ET-1 regulates salt excretion and blood pressure. We have reported the presence of an inner medullary collecting duct (IMCD)-specific enhancer region in the 5'-upstream ET-1 promoter (Strait, K. A... Reduced Plasma Membrane Expression of Dysferlin Mutants Is Attributed to Accelerated Endocytosis via a Syntaxin-4-associated Pathway [作者：Evesson, FJ; Peat, RA; Lek, A; Brilot, F; Lo, HP; Dale, RC; Parton, RG; North, KN; Cooper, ST,期刊：Journal of Biological Chemistry, 页码：28529-28539 , 文章类型： Article，,卷期：2010年285-37] Ferlins are an ancient family of C2 domain-containing proteins, with emerging roles in vesicular trafficking and human disease. Dysferlin mutations cause inherited muscular dystrophy, and dysferlin also shows abnormal pl... Human beta(1)-Adrenergic Receptor Is Subject to Constitutive and Regulated N-terminal Cleavage [作者：Hakalahti, AE; Vierimaa, MM; Lilja, MK; Kumpula, EP; Tuusa, JT; Petaja-Repo, UE,期刊：Journal of Biological Chemistry, 页码：28850-28861 , 文章类型： Article，,卷期：2010年285-37] The beta(1)-adrenergic receptor (beta(1)AR) is the predominant beta AR in the heart, mediating the catecholamine-stimulated increase in cardiac rate and force of contraction. Regulation of this important G protein-couple... Cholesterol Sulfate Alters Substrate Preference of Matrix Metalloproteinase-7 and Promotes Degradations of Pericellular Laminin-332 and Fibronectin [作者：Yamamoto, K; Miyazaki, K; Higashi, S,期刊：Journal of Biological Chemistry, 页码：28862-28873 , 文章类型： Article，,卷期：2010年285-37] Localization of secreted matrix metalloproteinases (MMPs) on the cell surface is required not only for processing of cell surface proteins, but also for controlled degradation of the extracellular matrix (ECM). Our previ... Superinhibitory Phospholamban Mutants Compete with Ca2+ for Binding to SERCA2a by Stabilizing a Unique Nucleotide-dependent Conformational State [作者：Akin, BL; Chen, ZH; Jones, LR,期刊：Journal of Biological Chemistry, 页码：28540-28552 , 文章类型： Article，,卷期：2010年285-37] Three cross-linkable phospholamban (PLB) mutants of increasing inhibitory strength (N30C-PLB < N27A,N30C,L37A-PLB (PLB3) < N27A,N30C,L37A,V49G-PLB (PLB4)) were used to determine whether PLB decreases the Ca2+ affinity of... p300-mediated Acetylation of Histone H3 Lysine 56 Functions in DNA Damage Response in Mammals [作者：Vempati, RK; Jayani, RS; Notani, D; Sengupta, A; Galande, S; Haldar, D,期刊：Journal of Biological Chemistry, 页码：28553-28564 , 文章类型： Article，,卷期：2010年285-37] The packaging of newly replicated and repaired DNA into chromatin is crucial for the maintenance of genomic integrity. Acetylation of histone H3 core domain lysine 56 (H3K56ac) has been shown to play a crucial role in co... Kinetics and Specificity of Feline Leukemia Virus Subgroup C Receptor (FLVCR) Export Function and Its Dependence on Hemopexin [作者：Yang, ZT; Philips, JD; Doty, RT; Giraudi, P; Ostrow, JD; Tiribelli, C; Smith, A; Abkowitz, JL,期刊：Journal of Biological Chemistry, 页码：28874-28882 , 文章类型： Article，,卷期：2010年285-37] The feline leukemia virus subgroup C receptor (FLVCR) is a heme export protein that is required for proerythroblast survival and facilitates macrophage heme iron recycling. However, its mechanism of heme export and subst...