- TNF alpha and IFN gamma Synergistically Enhance Transcriptional Activation of CXCL10 in Human Airway Smooth Muscle Cells via STAT-1, NF-kappa B, and the Transcriptional Coactivator CREB-binding Protein
[作者：Clarke, DL; Clifford, RL; Jindarat, S; Proud, D; Pang, LH; Belvisi, M; Knox, AJ,期刊：Journal of Biological Chemistry, 页码：29101-29110 , 文章类型： Article，,卷期：2010年285-38]
- Asthmatic airway smooth muscle (ASM) expresses interferon-gamma-inducible protein-10 (CXCL10), a chemokine known to mediate mast cell migration into ASM bundles that has been reported in the airways of asthmatic patients...
- HDMX-L Is Expressed from a Functional p53-responsive Promoter in the First Intron of the HDMX Gene and Participates in an Autoregulatory Feedback Loop to Control p53 Activity
[作者：Phillips, A; Teunisse, A; Lam, S; Lodder, K; Darley, M; Emaduddin, M; Wolf, A; Richter, J; de Lange, J; Verlaan-de Vries, M; Lenos, K; Bohnke, A; Bartel, F; Blaydes, JP; Jochemsen, AG,期刊：Journal of Biological Chemistry, 页码：29111-29127 , 文章类型： Article，,卷期：2010年285-38]
- The p53 regulatory network is critically involved in preventing the initiation of cancer. In unstressed cells, p53 is maintained at low levels and is largely inactive, mainly through the action of its two essential negat...
- Regulation of Skp2 Levels by the Pim-1 Protein Kinase
[作者：Cen, B; Mahajan, S; Zemskova, M; Beharry, Z; Lin, YW; Cramer, SD; Lilly, MB; Kraft, AS,期刊：Journal of Biological Chemistry, 页码：29128-29137 , 文章类型： Article，,卷期：2010年285-38]
- The Pim-1 protein kinase plays an important role in regulating both cell growth and survival and enhancing transformation by multiple oncogenes. The ability of Pim-1 to regulate cell growth is mediated, in part, by the c...
- T-LAK Cell-originated Protein Kinase (TOPK) Phosphorylation of Prx1 at Ser-32 Prevents UVB-induced Apoptosis in RPMI7951 Melanoma Cells through the Regulation of Prx1 Peroxidase Activity
[作者：Zykova, TA; Zhu, F; Vakorina, TI; Zhang, JS; Higgins, LA; Urusova, DV; Bode, AM; Dong, ZG,期刊：Journal of Biological Chemistry, 页码：29138-29146 , 文章类型： Article，,卷期：2010年285-38]
- Protein kinases are potential targets for the prevention and control of UV-induced skin cancer. T-cell-originated protein kinase (TOPK) is highly expressed in skin cancer cells, but its specific function is still unknown...
- IL-1-induced Post-transcriptional Mechanisms Target Overlapping Translational Silencing and Destabilizing Elements in I kappa B zeta mRNA
[作者：Dhamija, S; Doerrie, A; Winzen, R; Dittrich-Breiholz, O; Taghipour, A; Kuehne, N; Kracht, M; Holtmann, H,期刊：Journal of Biological Chemistry, 页码：29165-29178 , 文章类型： Article，,卷期：2010年285-38]
- The inflammatory cytokine IL-1 induces profound changes in gene expression. This is contributed in part by activating translation of a distinct set of mRNAs, including I kappa B zeta, as indicated by genome-wide analysis...
- Binding and Functional Properties of Five Extrinsic Proteins in Oxygen-evolving Photosystem II from a Marine Centric Diatom, Chaetoceros gracilis
[作者：Nagao, R; Moriguchi, A; Tomo, T; Niikura, A; Nakajima, S; Suzuki, T; Okumura, A; Iwai, M; Shen, JR; Ikeuchi, M; Enami, I,期刊：Journal of Biological Chemistry, 页码：29191-29199 , 文章类型： Article，,卷期：2010年285-38]
- Oxygen-evolving photosystem II (PSII) isolated from a marine centric diatom, Chaetoceros gracilis, contains a novel extrinsic protein (Psb31) in addition to four red algal type extrinsic proteins of PsbO, PsbQ', PsbV, an...
- The Reduction Potential of the Active Site Disulfides of Human Protein Disulfide Isomerase Limits Oxidation of the Enzyme by Ero1 alpha
[作者：Chambers, JE; Tavender, TJ; Oka, OBV; Warwood, S; Knight, D; Bulleid, NJ,期刊：Journal of Biological Chemistry, 页码：29200-29207 , 文章类型： Article，,卷期：2010年285-38]
- Disulfide formation in newly synthesized proteins entering the mammalian endoplasmic reticulum is catalyzed by protein disulfide isomerase (PDI), which is itself thought to be directly oxidized by Ero1 alpha. The activit...
- Insight into Invertebrate Defensin Mechanism of Action OYSTER DEFENSINS INHIBIT PEPTIDOGLYCAN BIOSYNTHESIS BY BINDING TO LIPID II
[作者：Schmitt, P; Wilmes, M; Pugniere, M; Aumelas, A; Bachere, E; Sahl, HG; Schneider, T; Destoumieux-Garzon, D,期刊：Journal of Biological Chemistry, 页码：29208-29216 , 文章类型： Article，,卷期：2010年285-38]
Three oyster defensin variants (Cg-Defh1, Cg-Defh2, and Cg-Defm) were produced as recombinant peptides and characterized in terms of activities and mechanism of action. In agreement with their spectrum of activity alm...
- MicroRNA 320a Functions as a Novel Endogenous Modulator of Aquaporins 1 and 4 as Well as a Potential Therapeutic Target in Cerebral Ischemia
[作者：Sepramaniam, S; Armugam, A; Lim, KY; Karolina, DS; Swaminathan, P; Tan, JR; Jeyaseelan, K,期刊：Journal of Biological Chemistry, 页码：29223-29230 , 文章类型： Article，,卷期：2010年285-38]
- Aquaporins facilitate efficient diffusion of water across cellular membranes, and water homeostasis is critically important in conditions such as cerebral edema. Changes in aquaporin 1 and 4 expression in the brain are a...
- Parkin Enhances the Expression of Cyclin-dependent Kinase 6 and Negatively Regulates the Proliferation of Breast Cancer Cells
[作者：Tay, SP; Yeo, CWS; Chai, C; Chua, PJ; Tan, HM; Ang, AXY; Yip, DLH; Sung, JX; Tan, PH; Bay, BH; Wong, SH; Tang, C; Tan, JMM; Lim, KL,期刊：Journal of Biological Chemistry, 页码：29231-29238 , 文章类型： Article，,卷期：2010年285-38]
- Although mutations in the parkin gene are frequently associated with familial Parkinsonism, emerging evidence suggests that parkin also plays a role in cancers as a putative tumor suppressor. Supporting this, we show her...
- Convergence of Ser/Thr and Two-component Signaling to Coordinate Expression of the Dormancy Regulon in Mycobacterium tuberculosis
[作者：Chao, JD; Papavinasasundaram, KG; Zheng, XJ; Chavez-Steenbock, A; Wang, XT; Lee, GQ; Av-Gay, Y,期刊：Journal of Biological Chemistry, 页码：29239-29246 , 文章类型： Article，,卷期：2010年285-38]
- Signal transduction in Mycobacterium tuberculosis is mediated primarily by the Ser/Thr protein kinases and the two-component systems. The Ser/Thr kinase PknH has been shown to regulate growth of M. tuberculosis in a mous...
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