- Glycan Analysis and Influenza A Virus Infection of Primary Swine Respiratory Epithelial Cells THE IMPORTANCE OF NeuAc alpha 2-6 GLYCANS
[作者:Bateman, AC; Karamanska, R; Busch, MG; Dell, A; Olsen, CW; Haslam, SM,期刊:Journal of Biological Chemistry, 页码:34016-34026 , 文章类型: Article,,卷期:2010年285-44]
- To better understand influenza virus infection of pigs, we examined primary swine respiratory epithelial cells (SRECs, the primary target cells of influenza viruses in vivo), as a model system. Glycomic profiling of SREC...
- Regulation of Human Cytidine Triphosphate Synthetase 2 by Phosphorylation
[作者:Kassel, KM; Au, DR; Higgins, MJ; Hines, M; Graves, LM,期刊:Journal of Biological Chemistry, 页码:33727-33736 , 文章类型: Article,,卷期:2010年285-44]
- Cytidine triphosphate synthetase (CTPS) is the rate-limiting enzyme in de novo CTP synthesis and is required for the formation of RNA, DNA, and phospholipids. This study determined the kinetic properties of the individua...
- A Dual Interface Determines the Recognition of RNA Polymerase II by RNA Capping Enzyme
[作者:Suh, MH; Meyer, PA; Gu, MG; Ye, P; Zhang, MC; Kaplan, CD; Lima, CD; Fu, JH,期刊:Journal of Biological Chemistry, 页码:34027-34038 , 文章类型: Article,,卷期:2010年285-44]
- RNA capping enzyme (CE) is recruited specifically to RNA polymerase II (Pol II) transcription sites to facilitate cotrans-criptional 5 '-capping of pre-mRNA and other Pol II transcripts. The current model to explain this...
- Association with beta-COP Regulates the Trafficking of the Newly Synthesized Na,K-ATPase
[作者:Morton, MJ; Farr, GA; Hull, M; Capendeguy, O; Horisberger, JD; Caplan, MJ,期刊:Journal of Biological Chemistry, 页码:33737-33746 , 文章类型: Article,,卷期:2010年285-44]
- Plasma membrane expression of the Na,K-ATPase requires assembly of its alpha- and beta-subunits. Using a novel labeling technique to identify Na,K-ATPase partner proteins, we detected an interaction between the Na,K-ATPa...
- An Exceptionally Potent Inducer of Cytoprotective Enzymes ELUCIDATION OF THE STRUCTURAL FEATURES THAT DETERMINE INDUCER POTENCY AND REACTIVITY WITH Keap1
[作者:Dinkova-Kostova, AT; Talalay, P; Sharkey, J; Zhang, Y; Holtzclaw, WD; Wang, XJ; David, E; Schiavoni, KH; Finlayson, S; Mierke, DF; Honda, T,期刊:Journal of Biological Chemistry, 页码:33747-33755 , 文章类型: Article,,卷期:2010年285-44]
- The Keap1/Nrf2/ARE pathway controls a network of cytoprotective genes that defend against the damaging effects of oxidative and electrophilic stress, and inflammation. Induction of this pathway is a highly effective stra...
- Prolyl Hydroxylase Domain (PHD) 2 Affects Cell Migration and F-actin Formation via RhoA/Rho-associated Kinase-dependent Cofilin Phosphorylation
[作者:Vogel, S; Wottawa, M; Farhat, K; Zieseniss, A; Schnelle, M; Le-Huu, S; von Ahlen, M; Malz, C; Camenisch, G; Katschinski, DM,期刊:Journal of Biological Chemistry, 页码:33756-33763 , 文章类型: Article,,卷期:2010年285-44]
- Cells are responding to hypoxia via prolyl-4-hydroxylase domain (PHD) enzymes, which are responsible for oxygen-dependent hydroxylation of the hypoxia-inducible factor (HIF)-1 alpha subunit. To gain further insight into ...
- Implications for Collagen Binding from the Crystallographic Structure of Fibronectin (6)FnI(1-2)FnII(7)FnI
[作者:Erat, MC; Schwarz-Linek, U; Pickford, AR; Farndale, RW; Campbell, ID; Vakonakis, I,期刊:Journal of Biological Chemistry, 页码:33764-33770 , 文章类型: Article,,卷期:2010年285-44]
- Collagen and fibronectin (FN) are two abundant and essential components of the vertebrate extracellular matrix; they interact directly with cellular receptors and affect cell adhesion and migration. Past studies identifi...
- Nucleoplasmin Binds Histone H2A-H2B Dimers through Its Distal Face
[作者:Ramos, I; Martin-Benito, J; Finn, R; Bretana, L; Aloria, K; Arizmendi, JM; Ausio, J; Muga, A; Valpuesta, JM; Prado, A,期刊:Journal of Biological Chemistry, 页码:33771-33778 , 文章类型: Article,,卷期:2010年285-44]
- Nucleoplasmin (NP) is a pentameric chaperone that regulates the condensation state of chromatin extracting specific basic proteins from sperm chromatin and depositing H2A-H2B histone dimers. It has been proposed that his...
- Activated PKC delta and PKC epsilon Inhibit Epithelial Chloride Secretion Response to cAMP via Inducing Internalization of the Na+-K+-2Cl(-) Cotransporter NKCC1
[作者:Tang, J; Bouyer, P; Mykoniatis, A; Buschmann, M; Matlin, KS; Matthews, JB,期刊:Journal of Biological Chemistry, 页码:34072-34085 , 文章类型: Article,,卷期:2010年285-44]
- The basolateral Na+-K+-2Cl(-)cotransporter (NKCC1) is a key determinant of transepithelial chloride secretion and dysregulation of chloride secretion is a common feature of many diseases including secretory diarrhea. We ...
- Involvement of 9-O-Acetyl GD3 Ganglioside in Mycobacterium leprae Infection of Schwann Cells
[作者:Ribeiro-Resende, VT; Ribeiro-Guimaraes, ML; Lemes, RMR; Nascimento, IC; Alves, L; Mendez-Otero, R; Pessolani, MCV; Lara, FA,期刊:Journal of Biological Chemistry, 页码:34086-34096 , 文章类型: Article,,卷期:2010年285-44]
- Mycobacterium leprae (ML), the etiologic agent of leprosy, mainly affects the skin and peripheral nerves, leading to demyelization and loss of axonal conductance. Schwann cells (SCs) are the main cell population infected...
- RNA-binding Protein Muscleblind-like 3 (MBNL3) Disrupts Myocyte Enhancer Factor 2 (Mef2) beta-Exon Splicing
[作者:Lee, KS; Cao, Y; Witwicka, HE; Tom, S; Tapscott, SJ; Wang, EH,期刊:Journal of Biological Chemistry, 页码:33779-33787 , 文章类型: Article,,卷期:2010年285-44]
- Mammalian MBNL (muscleblind-like) proteins are regulators of alternative splicing and have been implicated in myotonic dystrophy, the most common form of adult onset muscular dystrophy. MBNL3 functions as an inhibitor of...
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