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  • XAP2 inhibits glucocorticoid receptor activity in mammalian cells
    [作者:Laenger, A; Lang-Rollin, I; Kozany, C; Zschocke, J; Zimmermann, N; Ruegg, J; Holsboer, F; Hausch, F; Rein, T,期刊:FEBS Letters, 页码:1493-1498 , 文章类型: Article,,卷期:2009年583-9]
  • XAP2 is member of a protein family sharing the TPR protein interaction motif. It displays close homology to the immunophilins FKBP51 and FKBP52 that act via the Hsp90 folding machinery to regulate the glucocorticoid rece...
  • TNF-related apoptosis-inducing ligand suppresses PRDX4 expression
    [作者:Wang, HQ; Du, ZX; Liu, BQ; Gao, YY; Meng, X; Guan, YF; Zhang, HY,期刊:FEBS Letters, 页码:1511-1515 , 文章类型: Article,,卷期:2009年583-9]
  • TNF-related apoptosis-inducing ligand (TRAIL) is currently considered a promising target for developing anti-cancer therapies. Accumulating evidences have now shown that oxidative stress is involved in the TRAIL-mediated...
  • Essential role of p53 in TPEN-induced neuronal apoptosis
    [作者:Ra, H; Kim, HL; Lee, HW; Kim, YH,期刊:FEBS Letters, 页码:1516-1520 , 文章类型: Article,,卷期:2009年583-9]
  • Depletion of intracellular zinc with N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine (TPEN) induces protein synthesis-dependent apoptosis. In this study, we examined the requirement for p53 as an upstream transcriptio...
  • Hypoxia alters contractile protein homeostasis in L6 myotubes
    [作者:Caron, MA; Theriault, ME; Pare, ME; Maltais, F; Debigare, R,期刊:FEBS Letters, 页码:1528-1534 , 文章类型: Article,,卷期:2009年583-9]
  • Since hypoxia might contribute to the development of muscle atrophy, we wished to provide direct evidence linking hypoxia to muscle atrophy. By evaluating protein degradation and synthesis in hypoxic myotubes we found a ...