- The Drosophila homolog of methionine sulfoxide reductase A extends lifespan and increases nuclear localization of FOXO
[作者:Chung, H; Kim, AK; Jung, SA; Kim, SW; Yu, K; Lee, JH,期刊:FEBS Letters, 页码:3609-3614 , 文章类型: Article,,卷期:2010年584-16]
- Methionine sulfoxide reductase A (msrA) was previously found to increase resistance to oxidative stress and longevity in animals. We identified Drosophila msrA (dmsrA), a Drosophila homolog of human msrA, as a downstream...
- Ezetimibe stimulates faecal neutral sterol excretion depending on abcg8 function in mice
[作者:Jakulj, L; Vissers, MN; van Roomen, CP; van der Veen, JN; Vrins, CLJ; Kunne, C; Stellaard, F; Kastelein, JJP; Groen, AK,期刊:FEBS Letters, 页码:3625-3628 , 文章类型: Article,,卷期:2010年584-16]
- Ezetimibe stimulates faecal neutral sterol (FNS) excretion in mice, which cannot be explained by cholesterol absorption inhibition alone. We investigated whether these effects are mediated via the sterol exporter ATP bin...
- The oocyte-specific transcription factor, Nobox, regulates the expression of Pad6, a peptidylarginine deiminase in the oocyte
[作者:Choi, M; Lee, OH; Jeon, S; Park, M; Lee, DR; Ko, JJ; Yoon, TK; Rajkovic, A; Choi, Y,期刊:FEBS Letters, 页码:3629-3634 , 文章类型: Article,,卷期:2010年584-16]
- Nobox is an oocyte-specific transcriptional regulator. Nobox deficiency disrupts early folliculogenesis and the expression of oocyte-specific genes in mice. In the present study, we found that peptidylarginine deiminase ...
- From phenotype to gene: Detecting disease-specific gene functional modules via a text-based human disease phenotype network construction
[作者:Zhang, SH; Wu, C; Li, X; Chen, X; Jiang, W; Gong, BS; Li, JA; Yan, YQ,期刊:FEBS Letters, 页码:3635-3643 , 文章类型: Article,,卷期:2010年584-16]
- Currently, some efforts have been devoted to the text analysis of disease phenotype data, and their results indicated that similar disease phenotypes arise from functionally related genes. These related genes work togeth...
- Knock-out of metacaspase and/or cytochrome c results in the activation of a ROS-independent acetic acid-induced programmed cell death pathway in yeast
[作者:Guaragnella, N; Passarella, S; Marra, E; Giannattasio, S,期刊:FEBS Letters, 页码:3655-3660 , 文章类型: Article,,卷期:2010年584-16]
- To gain further insight into yeast acetic acid-induced programmed cell death (AA-PCD) we analyzed the effects of the antioxidant N-acetyl-L-cysteine (NAC) on cell viability, hydrogen peroxide (H2O2) production, DNA fragm...
- Osmoregulated trehalose-derived oligosaccharides in Sinorhizobium meliloti
[作者:Brique, A; Devassine, J; Pilard, S; Cailleu, D; Gosselin, I,期刊:FEBS Letters, 页码:3661-3666 , 文章类型: Article,,卷期:2010年584-16]
- Sinorhizobium meliloti is a soil bacterium accumulating glutamate, N-acetylglutaminyl glutamine amide and trehalose in hyperosmolarity. Besides these compatible solutes, we highlighted several compounds in S. meliloti Rm...
- Maintenance of red blood cell integrity by AMP-activated protein kinase alpha 1 catalytic subunit
[作者:Foretz, M; Guihard, S; Leclerc, J; Fauveau, V; Couty, JP; Andris, F; Gaudry, M; Andreelli, F; Vaulont, S; Viollet, B,期刊:FEBS Letters, 页码:3667-3671 , 文章类型: Article,,卷期:2010年584-16]
- AMP-activated protein kinase (AMPK) plays a pivotal role in regulating cellular energy metabolism. We previously showed that AMPK alpha 1-/- mice develop moderate anemia associated with splenomegaly and high reticulocyto...
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