- Influenza: Making Privileged Data Public Response
[作者:Fraser, C; Donnelly, CA; Cauchemez, S; Hanage, WP; Van Kerkhove, MD; Hollingsworth, TD; Griffin, J; Baggaley, RF; Jenkins, HE; Lyons, EJ; Jombart, T; Hinsley, WR; Grassly, NC; Balloux, F; Ghani, AC; Rambaut, A; Ferguson, NM,期刊:Science, 页码:1072-1073 , 文章类型: Letter,,卷期:2009年325-5944]
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- Good Genes and Good Luck: Ammonoid Diversity and the End-Permian Mass Extinction
[作者:Brayard, A; Escarguel, G; Bucher, H; Monnet, C; Bruhwiler, T; Goudemand, N; Galfetti, T; Guex, J,期刊:Science, 页码:1118-1121 , 文章类型: Article,,卷期:2009年325-5944]
- The end-Permian mass extinction removed more than 80% of marine genera. Ammonoid cephalopods were among the organisms most affected by this crisis. The analysis of a global diversity data set of ammonoid genera covering ...
- Eos Mediates Foxp3-Dependent Gene Silencing in CD4(+) Regulatory T Cells
[作者:Pan, F; Yu, H; Dang, EV; Barbi, J; Pan, XY; Grosso, JF; Jinasena, D; Sharma, SM; McCadden, EM; Getnet, D; Drake, CG; Liu, JO; Ostrowski, MC; Pardoll, DM,期刊:Science, 页码:1142-1146 , 文章类型: Article,,卷期:2009年325-5944]
- CD4(+) regulatory T cells (T-regs) maintain immunological self-tolerance and immune homeostasis by suppressing aberrant or excessive immune responses. The core genetic program of T-regs and their ability to suppress path...
- SDH5, a Gene Required for Flavination of Succinate Dehydrogenase, Is Mutated in Paraganglioma
[作者:Hao, HX; Khalimonchuk, O; Schraders, M; Dephoure, N; Bayley, JP; Kunst, H; Devilee, P; Cremers, CWRJ; Schiffman, JD; Bentz, BG; Gygi, SP; Winge, DR; Kremer, H; Rutter, J,期刊:Science, 页码:1139-1142 , 文章类型: Article,,卷期:2009年325-5944]
- Mammalian mitochondria contain about 1100 proteins, nearly 300 of which are uncharacterized. Given the well-established role of mitochondrial defects in human disease, functional characterization of these proteins may sh...
- The E3 Ligase TRAF6 Regulates Akt Ubiquitination and Activation
[作者:Yang, WL; Wang, J; Chan, CH; Lee, SW; Campos, AD; Lamothe, B; Hur, L; Grabiner, BC; Lin, X; Darnay, BG; Lin, HK,期刊:Science, 页码:1134-1138 , 文章类型: Article,,卷期:2009年325-5944]
- Akt signaling plays a central role in many biological functions, such as cell proliferation and apoptosis. Because Akt (also known as protein kinase B) resides primarily in the cytosol, it is not known how these signalin...
- Motile Cilia of Human Airway Epithelia Are Chemosensory
[作者:Shah, AS; Ben-Shahar, Y; Moninger, TO; Kline, JN; Welsh, MJ,期刊:Science, 页码:1131-1134 , 文章类型: Article,,卷期:2009年325-5944]
- Cilia are microscopic projections that extend from eukaryotic cells. There are two general types of cilia; primary cilia serve as sensory organelles, whereas motile cilia exert mechanical force. The motile cilia emerging...
- The Chemical Structure of a Molecule Resolved by Atomic Force Microscopy
[作者:Gross, L; Mohn, F; Moll, N; Liljeroth, P; Meyer, G,期刊:Science, 页码:1110-1114 , 文章类型: Article,,卷期:2009年325-5944]
- Resolving individual atoms has always been the ultimate goal of surface microscopy. The scanning tunneling microscope images atomic-scale features on surfaces, but resolving single atoms within an adsorbed molecule remai...
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