- Potent Vesicular Stomatitis Virus-Based Avian Influenza Vaccines Provide Long-Term Sterilizing Immunity against Heterologous Challenge
[作者:Schwartz, JA; Buonocore, L; Suguitan, AL; Silaghi, A; Kobasa, D; Kobinger, G; Feldmann, H; Subbarao, K; Rose, JK,期刊:Journal of virology, 页码:4611-4618 , 文章类型: Article,,卷期:2010年84-9]
- The emergence in 1997 and continuance today of a highly lethal H5N1 avian influenza virus (AIV) causing human disease has raised concern about an impending pandemic and the need for a vaccine to prepare for such an occur...
- Deubiquitinating and Interferon Antagonism Activities of Coronavirus Papain-Like Proteases
[作者:Clementz, MA; Chen, ZB; Banach, BS; Wang, YH; Sun, L; Ratia, K; Baez-Santos, YM; Wang, J; Takayama, J; Ghosh, AK; Li, K; Mesecar, AD; Baker, SC,期刊:Journal of virology, 页码:4619-4629 , 文章类型: Article,,卷期:2010年84-9]
- Coronaviruses encode multifunctional proteins that are critical for viral replication and for blocking the innate immune response to viral infection. One such multifunctional domain is the coronavirus papain-like proteas...
- Hepatitis B Virus Replication Induces Methylation of both Host and Viral DNA
[作者:Vivekanandan, P; Daniel, HDJ; Kannangai, R; Martinez-Murillo, F; Torbenson, M,期刊:Journal of virology, 页码:4321-4329 , 文章类型: Article,,卷期:2010年84-9]
- Control of viral replication is a major therapeutic goal to reduce morbidity and mortality from chronic hepatitis B virus (HBV) infection. Recently, methylation has been identified as a novel host defense mechanism, and ...
- Downregulation of Cdc2/CDK1 Kinase Activity Induces the Synthesis of Noninfectious Human Papillomavirus Type 31b Virions in Organotypic Tissues Exposed to Benzo[a] pyrene
[作者:Alam, S; Bowser, BS; Conway, MJ; Israr, M; Ryndock, EJ; Xi, LF; Meyers, C,期刊:Journal of virology, 页码:4630-4645 , 文章类型: Article,,卷期:2010年84-9]
- Epidemiological studies suggest that human papillomavirus (HPV)-infected women who smoke face an increased risk for developing cervical cancer. We have previously reported that exposure of HPV-positive organotypic cultur...
- CD317/Tetherin Is Enriched in the HIV-1 Envelope and Downregulated from the Plasma Membrane upon Virus Infection
[作者:Habermann, A; Krijnse-Locker, J; Oberwinkler, H; Eckhardt, M; Homann, S; Andrew, A; Strebel, K; Krausslich, HG,期刊:Journal of virology, 页码:4646-4658 , 文章类型: Article,,卷期:2010年84-9]
- CD317/Bst-2/tetherin is a host factor that restricts the release of human immunodeficiency virus type 1 (HIV-1) by trapping virions at the plasma membrane of certain producer cells. It is antagonized by the HIV-1 accesso...
- SDF-1/CXCL12 Production by Mature Dendritic Cells Inhibits the Propagation of X4-Tropic HIV-1 Isolates at the Dendritic Cell-T-Cell Infectious Synapse
[作者:Gonzalez, N; Bermejo, M; Calonge, E; Jolly, C; Arenzana-Seisdedos, F; Pablos, JL; Sattentau, QJ; Alcami, J,期刊:Journal of virology, 页码:4341-4351 , 文章类型: Article,,卷期:2010年84-9]
- An efficient mode of HIV-1 infection of CD4 lymphocytes occurs in the context of infectious synapses, where dendritic cells (DCs) enhance HIV-1 transmission to lymphocytes. Emergence of CXCR4-using (X4) HIV-1 strains occ...
- Numerous Conserved and Divergent MicroRNAs Expressed by Herpes Simplex Viruses 1 and 2
[作者:Jurak, I; Kramer, MF; Mellor, JC; van Lint, AL; Roth, FP; Knipe, DM; Coen, DM,期刊:Journal of virology, 页码:4659-4672 , 文章类型: Article,,卷期:2010年84-9]
- Certain viruses use microRNAs (miRNAs) to regulate the expression of their own genes, host genes, or both. Previous studies have identified a limited number of miRNAs expressed by herpes simplex viruses 1 and 2 (HSV-1 an...
- The Lack of an Inherent Membrane Targeting Signal Is Responsible for the Failure of the Matrix (M1) Protein of Influenza A Virus To Bud into Virus-Like Particles
[作者:Wang, D; Harmon, A; Jin, J; Francis, DH; Christopher-Hennings, J; Nelson, E; Montelaro, RC; Li, F,期刊:Journal of virology, 页码:4673-4681 , 文章类型: Article,,卷期:2010年84-9]
- The matrix protein (M1) of influenza A virus is generally viewed as a key orchestrator in the release of influenza virions from the plasma membrane during infection. In contrast to this model, recent studies have indicat...
- T-Cell Correlates of Vaccine Efficacy after a Heterologous Simian Immunodeficiency Virus Challenge
[作者:Martins, MA; Wilson, NA; Reed, JS; Ahn, CD; Klimentidis, YC; Allison, DB; Watkins, DI,期刊:Journal of virology, 页码:4352-4365 , 文章类型: Article,,卷期:2010年84-9]
- Determining the "correlates of protection" is one of the challenges in human immunodeficiency virus vaccine design. To date, T-cell-based AIDS vaccines have been evaluated with validated techniques that measure the numbe...
- Reciprocal Regulation of AKT and MAP Kinase Dictates Virus-Host Cell Fusion
[作者:Sharma, NR; Mani, P; Nandwani, N; Mishra, R; Rana, A; Sarkar, DP,期刊:Journal of virology, 页码:4366-4382 , 文章类型: Article,,卷期:2010年84-9]
- Viruses of the Paramyxoviridae family bind to their host cells by using hemagglutinin-neuraminidase (HN), which enhances fusion protein (F)-mediated membrane fusion. Although respiratory syncytial virus and parainfluenza...
- Sumoylation of the Epstein-Barr Virus BZLF1 Protein Inhibits Its Transcriptional Activity and Is Regulated by the Virus-Encoded Protein Kinase
[作者:Hagemeier, SR; Dickerson, SJ; Meng, Q; Yu, XM; Mertz, JE; Kenney, SC,期刊:Journal of virology, 页码:4383-4394 , 文章类型: Article,,卷期:2010年84-9]
- The Epstein-Barr virus (EBV) immediate-early protein BZLF1 (Z) mediates the switch between latent and lytic EBV infection. Z not only activates early lytic viral gene transcription but also plays a direct role in lytic v...
- Structural Insights into the Molecular Mechanisms of Cauliflower Mosaic Virus Transmission by Its Insect Vector
[作者:Hoh, F; Uzest, M; Drucker, M; Plisson-Chastang, C; Bron, P; Blanc, S; Dumas, C,期刊:Journal of virology, 页码:4706-4713 , 文章类型: Article,,卷期:2010年84-9]
- Cauliflower mosaic virus (CaMV) is transmitted from plant to plant through a seemingly simple interaction with insect vectors. This process involves an aphid receptor and two viral proteins, P2 and P3. P2 binds to both t...
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