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文章名     作者     期刊名     摘要     卷     期         如果没有找到您所需要的文献，请点击 ——此处申请     共21条记录   Silk-elastinlike recombinant polymers for gene therapy of head and neck cancer: From molecular definition to controlled gene expression [作者：Gustafson, J; Greish, K; Frandsen, J; Cappello, J; Ghandehari, H,期刊：Journal of controlled release, 页码：256-261 , 文章类型： Proceedings Paper，,卷期：2009年140-3] Silk-elastinlike protein polymers (SELP's) are block copolymers of silk-like and elastin-like tandem repeats. With appropriate sequence and composition SELPs can be liquid at room temperature and form hydrogels at body t... Gene expression and silencing for improved islet transplantation [作者：Mahato, RI,期刊：Journal of controlled release, 页码：262-267 , 文章类型： Proceedings Paper，,卷期：2009年140-3] Islet transplantation has great potential as an effective means of treating type l diabetes. However, its successful application greatly depends on the rapid revascularization of islets and prevention from their apoptoti... Anionic amino acid-derived cationic lipid for siRNA delivery [作者：Suh, MS; Shim, G; Lee, HY; Han, SE; Yu, YH; Choi, Y; Kim, K; Kwon, IC; Weon, KY; Kim, YB; Oh, YK,期刊：Journal of controlled release, 页码：268-276 , 文章类型： Proceedings Paper，,卷期：2009年140-3] Viable siRNA therapeutic strategies require the concurrent development of effective and safe delivery systems. Here, we described the synthesis of a new cationic lipid, N,N ''-dioleylglutamide (DG), and evaluated DG-base... Novel biodegradable lipid nano complex for siRNA delivery significantly improving the chemosensitivity of human colon cancer stem cells to paclitaxel [作者：Liu, CX; Zhao, G; Liu, J; Ma, NC; Chivukula, P; Perelman, L; Okada, K; Chen, ZY; Gough, D; Yu, L,期刊：Journal of controlled release, 页码：277-283 , 文章类型： Proceedings Paper，,卷期：2009年140-3] Background: Targeting of a specific subset of cells is mandatory for the successful application of siRNA mediated silencing in anticancer therapy. A recent theory suggests that colon cancer is sustained by a small subpop... Surface-engineered targeted PPI dendrimer for efficient intracellular and intratumoral siRNA delivery [作者：Taratula, O; Garbuzenko, OB; Kirkpatrick, P; Pandya, I; Savla, R; Pozharov, VP; He, HX; Minko, T,期刊：Journal of controlled release, 页码：284-293 , 文章类型： Proceedings Paper，,卷期：2009年140-3] Low penetration ability of Small Interfering RNA (siRNA) through the cellular plasma membrane combined with its limited stability in blood, limits the effectiveness of the systemic delivery of siRNA. In order to overcome...