- Phase II Trial of Combination Therapy With Bortezomib, Pegylated Liposomal Doxorubicin, and Dexamethasone in Patients With Newly Diagnosed Myeloma
[作者:Jakubowiak, AJ; Kendall, T; Al-Zoubi, A; Khaled, Y; Mineishi, S; Ahmed, A; Campagnaro, E; Brozo, C; Braun, T; Talpaz, M; Kaminski, MS,期刊:Journal of clinical oncology, 页码:5015-5022 , 文章类型: Proceedings Paper,,卷期:2009年27-30]
- Purpose This single-center, open-label, phase II trial evaluated the bortezomib, pegylated liposomal doxorubicin (PLD), and dexamethasone combination regimen (VDD) as initial treatment for patients with newly diagnosed m...
- Multicenter Randomized Phase II Study of Weekly or Twice-Weekly Bortezomib Plus Rituximab in Patients With Relapsed or Refractory Follicular or Marginal-Zone B-Cell Lymphoma
[作者:de Vos, S; Goy, A; Dakhil, SR; Saleh, MN; McLaughlin, P; Belt, R; Flowers, CR; Knapp, M; Hart, L; Patel-Donnelly, D; Glenn, M; Gregory, SA; Holladay, C; Zhang, T; Boral, AL,期刊:Journal of clinical oncology, 页码:5023-5030 , 文章类型: Article,,卷期:2009年27-30]
- Purpose To determine overall response rate (ORR), time to progression (TTP), and duration of response (DOR) with twice-weekly/weekly bortezomib plus rituximab, and evaluate safety/tolerability, in patients with relapsed ...
- ERG Expression Is an Independent Prognostic Factor and Allows Refined Risk Stratification in Cytogenetically Normal Acute Myeloid Leukemia: A Comprehensive Analysis of ERG, MN1, and BAALC Transcript Levels Using Oligonucleotide Microarrays
[作者:Metzeler, KH; Dufour, A; Benthaus, T; Hummel, M; Sauerland, MC; Heinecke, A; Berdel, WE; Buchner, T; Wormann, B; Mansmann, U; Braess, J; Spiekermann, K; Hiddemann, W; Buske, C; Bohlander, SK,期刊:Journal of clinical oncology, 页码:5031-5038 , 文章类型: Article,,卷期:2009年27-30]
- Purpose Recently, several novel molecular prognostic markers were identified in cytogenetically normal acute myeloid leukemia (CN-AML). In addition to the well-known influence of FLT3, NPM1, and CEBPA mutations, high tra...
- Immunophenotypic Analysis of AIDS-Related Diffuse Large B-Cell Lymphoma and Clinical Implications in Patients From AIDS Malignancies Consortium Clinical Trials 010 and 034
[作者:Chadburn, A; Chiu, A; Lee, JY; Chen, X; Hyjek, E; Banham, AH; Noy, A; Kaplan, LD; Sparano, JA; Bhatia, K; Cesarman, E,期刊:Journal of clinical oncology, 页码:5039-5048 , 文章类型: Article,,卷期:2009年27-30]
- Purpose Diffuse large B-cell lymphoma (DLBCL) represents a clinically heterogeneous disease. Models based on immunohistochemistry predict clinical outcome. These include subdivision into germinal center (GC) versus non-G...
- Serum Adiponectin As a Predictor of Childhood Non-Hodgkin's Lymphoma: A Nationwide Case-Control Study
[作者:Petridou, ET; Sergentanis, TN; Dessypris, N; Vlachantoni, IT; Tseleni-Balafouta, S; Pourtsidis, A; Moschovi, M; Polychronopoulou, S; Athanasiadou-Piperopoulou, F; Kalmanti, M; Mantzoros, CS,期刊:Journal of clinical oncology, 页码:5049-5055 , 文章类型: Article,,卷期:2009年27-30]
- Purpose To our knowledge, this is the first study exploring the association of childhood non-Hodgkin's lymphoma (NHL) with serum adiponectin and leptin levels in a nationwide case-control series. In addition, expression ...
- Single-Drug Vinblastine As Salvage Treatment for Refractory or Relapsed Anaplastic Large-Cell Lymphoma: A Report From the French Society of Pediatric Oncology
[作者:Brugieres, L; Pacquement, H; Le Deley, MC; Leverger, G; Lutz, P; Paillard, C; Baruchel, A; Frappaz, D; Nelken, B; Lamant, L; Patte, C,期刊:Journal of clinical oncology, 页码:5056-5061 , 文章类型: Article,,卷期:2009年27-30]
- Purpose To evaluate the efficacy of vinblastine for relapsed/refractory anaplastic large-cell lymphoma (ALCL). Patients and Methods Data were reviewed on all 36 patients included prospectively in the French database for ...
- Long-Term Results of a Randomized Trial of Surgery With or Without Preoperative Chemotherapy in Esophageal Cancer
[作者:Allum, WH; Stenning, SP; Bancewicz, J; Clark, PI; Langley, RE,期刊:Journal of clinical oncology, 页码:5062-5067 , 文章类型: Article,,卷期:2009年27-30]
- Purpose OEO2 is a randomized, controlled trial of preoperative chemotherapy in patients undergoing radical surgery for esophageal cancer. Random assignment was to surgery alone (S) or to two cycles of combination cisplat...
- Amphiregulin and Epiregulin mRNA Expression in Primary Tumors Predicts Outcome in Metastatic Colorectal Cancer Treated With Cetuximab
[作者:Jacobs, B; De Roock, W; Piessevaux, H; Van Oirbeek, R; Biesmans, B; De Schutter, J; Fieuws, S; Vandesompele, J; Peeters, M; Van Laethem, JL; Humblet, Y; Penault-Llorca, F; De Hertogh, G; Laurent-Puig, P; Van Cutsem, E; Tejpar, S,期刊:Journal of clinical oncology, 页码:5068-5074 , 文章类型: Article,,卷期:2009年27-30]
- Purpose To study the power of the epidermal growth factor receptor (EGFR) epiregulin (EREG) and amphiregulin (AREG) ligands' expression in primary tumors to predict the outcome in patients with chemorefractory metastatic...
- Risk of Fracture After Single Fraction Image-Guided Intensity-Modulated Radiation Therapy to Spinal Metastases
[作者:Rose, PS; Laufer, I; Boland, PJ; Hanover, A; Bilsky, MH; Yamada, J; Lis, E,期刊:Journal of clinical oncology, 页码:5075-5079 , 文章类型: Article,,卷期:2009年27-30]
- Purpose Single-fraction image-guided intensity-modulated radiation therapy (IG-IMRT) allows for tumoricidal treatment of traditionally radioresistant cancers while sparing critical adjacent structures. Risk of vertebral ...
- Randomized, Placebo-Controlled, Phase II Study of Sequential Erlotinib and Chemotherapy As First-Line Treatment for Advanced Non-Small-Cell Lung Cancer
[作者:Mok, TSK; Wu, YL; Yu, CJ; Zhou, C; Chen, YM; Zhang, L; Ignacio, J; Liao, M; Srimuninnimit, V; Boyer, MJ; Chua-Tan, M; Sriuranpong, V; Sudoyo, AW; Jin, K; Johnston, M; Chui, W; Lee, JS,期刊:Journal of clinical oncology, 页码:5080-5087 , 文章类型: Article,,卷期:2009年27-30]
- Purpose This study investigated whether sequential administration of erlotinib and chemotherapy improves clinical outcomes versus chemotherapy alone in unselected, chemotherapy-naive patients with advanced non-small-cell...
- Low Initial Human Papilloma Viral Load Implicates Worse Prognosis in Patients With Uterine Cervical Cancer Treated With Radiotherapy
[作者:Kim, JY; Park, S; Nam, BH; Roh, JW; Lee, CH; Kim, YH; Shin, HJ; Lee, SK; Kong, SY; Seong, MW; Han, TJ; Lee, MY; Cho, KH; Park, SY,期刊:Journal of clinical oncology, 页码:5088-5093 , 文章类型: Article,,卷期:2009年27-30]
- Purpose To evaluate whether human papillomavirus (HPV) viral load measured in cervical smear and HPV type 18 are associated with radiotherapy outcomes in uterine cervical cancer. Patients and Methods HPV DNA was semiquan...
- Phase I Pharmacokinetic and Pharmacodynamic Study of the Aurora Kinase Inhibitor Danusertib in Patients With Advanced or Metastatic Solid Tumors
[作者:Steeghs, N; Eskens, FALM; Gelderblom, H; Verweij, J; Nortier, JWR; Ouwerkerk, J; van Noort, C; Mariani, M; Spinelli, R; Carpinelli, P; Laffranchi, B; de Jonge, MJA,期刊:Journal of clinical oncology, 页码:5094-5101 , 文章类型: Article,,卷期:2009年27-30]
- Purpose Danusertib (PHA-739358) is a small-molecule pan-aurora kinase inhibitor. This phase I dose escalation study was conducted to evaluate safety and tolerability of danusertib with additional pharmacokinetic, biomark...
- Phase I and Pharmacokinetic Study of Cetuximab and Irinotecan in Children With Refractory Solid Tumors: A Study of the Pediatric Oncology Experimental Therapeutic Investigators' Consortium
[作者:Trippett, TM; Herzog, C; Whitlock, JA; Wolff, J; Kuttesch, J; Bagatell, R; Hunger, SP; Boklan, J; Smith, AA; Arceci, RJ; Katzenstein, HM; Harbison, C; Zhou, XF; Lu, HL; Langer, C; Weber, M; Gore, L,期刊:Journal of clinical oncology, 页码:5102-5108 , 文章类型: Article,,卷期:2009年27-30]
- Purpose To determine the dose of cetuximab that can be safely combined with irinotecan for treatment of pediatric and adolescent patients with refractory solid tumors. Patients and Methods This open-label, phase I study ...
- Improving Cancer Outcomes Through International Collaboration in Academic Cancer Treatment Trials
[作者:Trimble, EL; Abrams, JS; Meyer, RM; Calvo, F; Cazap, E; Deye, J; Eisenhauer, E; Fitzgerald, TJ; Lacombe, D; Parmar, M; Seibel, N; Shankar, L; Swart, AM; Therasse, P; Vikram, B; von Frenckell, R; Friedlander, M; Fujiwara, K; Kaplan, RS; Meunier, F,期刊:Journal of clinical oncology, 页码:5109-U194 , 文章类型: Review,,卷期:2009年27-30]
- Purpose The need for international collaboration in cancer clinical trials has grown stronger as we have made progress both in cancer treatment and screening. We sought to identify those efforts already underway which fa...
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