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文章名     作者     期刊名     摘要     卷     期         如果没有找到您所需要的文献，请点击 ——此处申请     共44条记录   A Novel Role for the Dioxin Receptor in Fatty Acid Metabolism and Hepatic Steatosis [作者：Lee, JH; Wada, T; Febbraio, M; He, JH; Matsubara, T; Lee, MJ; Gonzalez, FJ; Xie, W,期刊：Gastroenterology, 页码：653-663 , 文章类型： Article，,卷期：2010年139-2] BACKGROUND & AIMS: The aryl hydrocarbon receptor (AhR) also known as the dioxin receptor or xenobiotic receptor is a member of the basic helix-loop-helix/period AhR nuclear translocator single minded family. The goal of ... Complement and Alcoholic Liver Disease: Role of C1q in the Pathogenesis of Ethanol-Induced Liver Injury in Mice [作者：Cohen, JI; Roychowdhury, S; Mcmullen, MR; Stavitsky, AB; Nagy, LE,期刊：Gastroenterology, 页码：664-674 , 文章类型： Article，,卷期：2010年139-2] BACKGROUND & AIMS: Complement is involved in the development of alcoholic liver disease in mice; however, the mechanisms for complement activation during ethanol exposure have not been identified. C1q, the recognition su... Changes in Risk Factors and Increases in Screening Contribute to the Decline in Colorectal Cancer Mortality, 1975 to 2000 [作者：Zauber, AG; Lansdorp-Vogelaar, I,期刊：Gastroenterology, 页码：698-698 , 文章类型： Letter，,卷期：2010年139-2] Hyperammonemia Induces Neuroinflammation That Contributes to Cognitive Impairment in Rats With Hepatic Encephalopathy [作者：Rodrigo, R; Cauli, O; Gomez-Pinedo, U; Agusti, A; Hernandez-Rabaza, V; Garcia-Verdugo, JM; Felipo, V,期刊：Gastroenterology, 页码：675-684 , 文章类型： Article，,卷期：2010年139-2] BACKGROUND & AIMS: Hyperammonemia and inflammation cooperate to induce neurological alterations in hepatic encephalopathy. Recent studies in animal models suggest that chronic hyperammonemia and neuroinflammation impair ... Increased Fibroblast Growth Factor 21 in Obesity and Nonalcoholic Fatty Liver Disease [作者：Dushay, J; Chui, PC; Gopalakrishnan, GS; Varela-Rey, M; Crawley, M; Fisher, FM; Badman, MK; Martinez-Chantar, ML; Maratos-Flier, E,期刊：Gastroenterology, 页码：456-463 , 文章类型： Article，,卷期：2010年139-2] BACKGROUND & AIMS: Fibroblast growth factor 21 (FGF21) is an hepatic protein that plays a critical role in metabolism, stimulating fatty acid oxidation in liver and glucose uptake in Eat. Systemic administration to obese... Insulin-Like Growth Factor Axis Gene Polymorphisms and Clinical Outcomes in Pancreatic Cancer [作者：Dong, XQ; Javle, M; Hess, KR; Shroff, R; Abbruzzese, JL; Li, DH,期刊：Gastroenterology, 页码：464-473 , 文章类型： Article，,卷期：2010年139-2] BACKGROUND & AIMS: Insulin-like growth factor (IGF)-axis mediated signaling pathways play an important role in pancreatic cancer development and progression. We examined whether IGF-axis gene variants are associated with... Incidence and Determinants of Spontaneous Hepatitis B Surface Antigen Seroclearance: A Community-Based Follow-up Study [作者：Liu, J; Yang, HI; Lee, MH; Lu, SN; Jen, CL; Wang, LY; You, SL; Iloeje, UH; Chen, CJ,期刊：Gastroenterology, 页码：474-482 , 文章类型： Article，,卷期：2010年139-2] BACKGROUND & AIMS: Seroclearance of hepatitis B surface antigen (HBsAg) is one of the most important clinical outcomes for chronic hepatitis B treatment trials. Few studies have explored the incidence and determinants of... Nucleos(t)ide Analogues Only Induce Temporary Hepatitis B e Antigen Seroconversion in Most Patients With Chronic Hepatitis B [作者：Reijnders, JGP; Perquin, MJ; Zhang, NP; Hansen, BE; Janssen, HLA,期刊：Gastroenterology, 页码：491-498 , 文章类型： Article，,卷期：2010年139-2] BACKGROUND & AIMS: Inconsistencies in results and guideline recommendations regarding the durability of nucleos(t)ide analogue-induced hepatitis B e antigen (HBeAg) seroconversion require clarification. We studied the lo... Hepatitis B Surface Antigen Serum Levels Help to Distinguish Active From Inactive Hepatitis B Virus Genotype D Carriers [作者：Brunetto, MR; Oliveri, F; Colombatto, P; Moriconi, F; Ciccoross, P; Coco, B; Romagnoli, V; Cherubini, B; Moscato, G; Maina, AM; Cavallone, D; Bonino, F,期刊：Gastroenterology, 页码：483-490 , 文章类型： Article，,卷期：2010年139-2] BACKGROUND & AIMS: The accurate identification of (serum HBV-DNA persistently <= 2000 IU/mL) hepatitis B virus (HBV) carriers (IC) is difficult because of wide and frequent HBV-DNA fluctuations. We studied whether hepati... Hepatic ISG Expression Is Associated With Genetic Variation in Interleukin 28B and the Outcome of IFN Therapy for Chronic Hepatitis C [作者：Honda, M; Sakai, A; Yamashita, T; Nakamoto, Y; Mizukoshi, E; Sakai, Y; Yamashita, T; Nakamura, M; Shirasaki, T; Horimoto, K; Tanaka, Y; Tokunaga, K; Mizokami, M; Kaneko, S,期刊：Gastroenterology, 页码：499-509 , 文章类型： Article，,卷期：2010年139-2] BACKGROUND & AIMS: Multiple viral and host factors are related to the treatment response to pegylated-interferon and ribavirin combination therapy; however, the clinical relevance and relationship of these factors have n... Improving the Inhibitory Control Task to Detect Minimal Hepatic Encephalopathy [作者：Amodio, P; Ridola, L; Schiff, S; Montagnese, S; Pasquale, C; Nardelli, S; Pentassuglio, I; Trezza, M; Marzano, C; Flaiban, C; Angeli, P; Cona, G; Bisiacchi, P; Gatta, A; Riggio, O,期刊：Gastroenterology, 页码：510-518 , 文章类型： Article，,卷期：2010年139-2] BACKGROUND & AIMS: Quantification of the number of noninhibited responses (lures) in the inhibitory control task (ICT) has been proposed for the diagnosis of minimal hepatic encephalopathy (MHE). We assessed the efficacy... Paired Immunoglobulin-Like Receptor B (PIR-B) Negatively Regulates Macrophage Activation in Experimental Colitis [作者：Munitz, A; Cole, ET; Beichler, A; Groschwitz, K; Ahrens, R; Steinbrecher, K; Willson, T; Han, XN; Denson, L; Rothenberg, ME; Hogan, SP,期刊：Gastroenterology, 页码：530-541 , 文章类型： Article，,卷期：2010年139-2] BACKGROUND & AIMS: Innate and adaptive immune responses are regulated by cross talk between activation and inhibitory signals. Dysregulation of the inhibitory signal can lead to aberrant chronic inflammatory diseases suc... Pathogenic and Protective Roles of MyD88 in Leukocytes and Epithelial Cells in Mouse Models of Inflammatory Bowel Disease [作者：Asquith, MJ; Boulard, O; Powrie, F; Maloy, KJ,期刊：Gastroenterology, 页码：519-529 , 文章类型： Article，,卷期：2010年139-2] BACKGROUND & AIMS: Toll-like receptors (TLR) are innate immune receptors involved in recognition of the intestinal microflora; they are expressed by numerous cell types in the intestine, including epithelial cells, myelo... Clostridium difficile Toxin-Induced Inflammation and Intestinal Injury Are Mediated by the Inflammasome [作者：Ng, J; Hirota, SA; Gross, O; Li, Y; Ulke-Lemee, A; Potentier, MS; Schenck, LP; Vilaysane, A; Seamone, ME; Feng, HP; Armstrong, GD; Tschopp, J; Macdonald, JA; Muruve, DA; Beck, PL,期刊：Gastroenterology, 页码：542-552 , 文章类型： Article，,卷期：2010年139-2] BACKGROUND & AIMS: Clostridium difficile-associated disease (CDAD) is the leading cause of nosocomial diarrhea in the United States. C difficile toxins TcdA and TcdB breach the intestinal barrier and trigger mucosal infl... Evidence of Central and Peripheral Sensitization in a Rat Model of Narcotic Bowel-Like Syndrome [作者：Agostini, S; Eutamene, H; Cartier, C; Broccardo, M; Improta, G; Houdeau, E; Petrella, C; Ferrier, L; Theodorou, V; Bueno, L,期刊：Gastroenterology, 页码：553-563 , 文章类型： Article，,卷期：2010年139-2] BACKGROUND & AIMS: Narcotic bowel syndrome (NBS) is a subset of opioid bowel dysfunctions that results from prolonged treatment with narcotics and is characterized by chronic abdominal pain. NBS is under-recognized and i... Loss of Single Immunoglobulin Interlukin-1 Receptor-Related Molecule Leads to Enhanced Colonic Polyposis in Apc(min) Mice [作者：Xiao, H; Yin, WG; Khan, MA; Gulen, MF; Zhou, H; Sham, HP; Jacobson, K; Vallance, BA; Li, XX,期刊：Gastroenterology, 页码：574-585 , 文章类型： Article，,卷期：2010年139-2] BACKGROUND & AIMS: Commensal bacteria can activate signaling by the Toll-like and interleukin-1 receptors (TLR and IL-1R) to mediate pathogenesis of inflammatory bowel diseases and colitis-associated cancer. We investiga...