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  • Hedgehog controls neural stem cells through p53-independent regulation of Nanog
    [作者:Po, A; Ferretti, E; Miele, E; De Smaele, E; Paganelli, A; Canettieri, G; Coni, S; Di Marcotullio, L; Biffoni, M; Massimi, L; Di Rocco, C; Screpanti, I; Gulino, A,期刊:EMBO journal, 页码:2646-2658 , 文章类型: Article,,卷期:2010年29-15]
  • Hedgehog (Hh) pathway has a pivotal function in development and tumorigenesis, processes sustained by stem cells (SCs). The transcription factor Nanog controls stemness acting as a key determinant of both embryonic SC se...