- Regenerative Effects of Transplanted Mesenchymal Stem Cells in Fracture Healing
[作者:Granero-Molto, F; Weis, JA; Miga, MI; Landis, B; Myers, TJ; O'Rear, L; Longobardi, L; Jansen, ED; Mortlock, DP; Spagnoli, A,期刊:Stem Cells, 页码:1887-1898 , 文章类型: Article,,卷期:2009年27-8]
- Mesenchymal stem cells (MSC) have a therapeutic potential in patients with fractures to reduce the time of healing and treat nonunions. The use of MSC to treat fractures is attractive for several reasons. First, MSCs wou...
- Adult Palatum as a Novel Source of Neural Crest-Related Stem Cells
[作者:Widera, D; Zander, C; Heidbreder, M; Kasperek, Y; Noll, T; Seitz, O; Saldamli, B; Sudhoff, H; Sader, R; Kaltschmidt, C; Kaltschmidt, B,期刊:Stem Cells, 页码:1899-1910 , 文章类型: Article,,卷期:2009年27-8]
- Somatic neural and neural crest stem cells are promising sources for cellular therapy of several neurodegenerative diseases. However, because of practical considerations such as inadequate accessibility of the source mat...
- c-Kit Function Is Necessary for In Vitro Myogenic Differentiation of Bone Marrow Hematopoietic Cells
[作者:Xaymardan, M; Cimini, M; Fazel, S; Weisel, RD; Lu, WY; Martin, U; Harvey, RP; Li, RK,期刊:Stem Cells, 页码:1911-1920 , 文章类型: Article,,卷期:2009年27-8]
- In recent years, the differentiation of bone marrow cells (BMCs) into myocytes has been extensively investigated, but the findings remain inconclusive. The purpose of this study was to determine the conditions necessary ...
- Microgel Iron Oxide Nanoparticles for Tracking Human Fetal Mesenchymal Stem Cells Through Magnetic Resonance Imaging
[作者:Lee, ESM; Chan, J; Shuter, B; Tan, LG; Chong, MSK; Ramachandra, DL; Dawe, GS; Ding, J; Teoh, SH; Beuf, O; Briguet, A; Tam, KC; Choolani, M; Wang, SC,期刊:Stem Cells, 页码:1921-1931 , 文章类型: Article,,卷期:2009年27-8]
- Stem cell transplantation for regenerative medicine has made significant progress in various injury models, with the development of modalities to track stem cell fate and migration post-transplantation being currently pu...
- Noninvasive Bioluminescent Imaging Demonstrates Long-Term Multilineage Engraftment of Ex Vivo-Expanded CD34-Selected Umbilical Cord Blood Cells
[作者:Steiner, D; Gelovani, J; Savoldo, B; Robinson, SN; Decker, WK; Brouard, N; Najjar, A; Xing, DX; Yang, H; Li, SF; Marini, F; Zweidler-McKay, PA; Bollard, CM; Shpall, EJ; Dotti, G; Simmons, PJ,期刊:Stem Cells, 页码:1932-1940 , 文章类型: Article,,卷期:2009年27-8]
- The use of umbilical cord blood (UCB) grafts for hematopoietic stem cell transplantation (HSCT) is a promising technique that permits a degree of human leukocyte antigen mismatch between the graft and the host without th...
- Generation of Pancreatic Hormone-Expressing Islet-Like Cell Aggregates from Murine Adipose Tissue-Derived Stem Cells
[作者:Chandra, V; Swetha, G; Phadnis, S; Nair, PD; Bhonde, RR,期刊:Stem Cells, 页码:1941-1953 , 文章类型: Article,,卷期:2009年27-8]
- The success of cell replacement therapy for diabetes depends on the availability and generation of an adequate number of islets, preferably from an autologous origin. Stem cells are now being probed for the generation of...
- Species Variation in the Mechanisms of Mesenchymal Stem Cell-Mediated Immunosuppression
[作者:Ren, GW; Su, JJ; Zhang, LY; Zhao, X; Ling, WF; L'Huillie, A; Zhang, JM; Lu, YQ; Roberts, AI; Ji, WZ; Zhang, HT; Rabson, AB; Shi, YF,期刊:Stem Cells, 页码:1954-1962 , 文章类型: Article,,卷期:2009年27-8]
- Bone marrow-derived mesenchymal stem cells (MSCs) hold great promise for treating immune disorders because of their immunoregulatory capacity, but the mechanism remains controversial. As we show here, the mechanism of MS...
- Senescent Growth Arrest in Mesenchymal Stem Cells Is Bypassed by Wip1-Mediated Downregulation of Intrinsic Stress Signaling Pathways
[作者:Lee, JS; Lee, MO; Moon, BH; Shim, SH; Fornace, AJ; Cha, HJ,期刊:Stem Cells, 页码:1963-1975 , 文章类型: Article,,卷期:2009年27-8]
- Human mesenchymal stem cells (hMSCs) have been widely studied as a source of primary adult stem cells for cell therapy because of their multidifferentiation potential; however, the growth arrest (also known as "premature...
- Locally Delivered Growth Factor Enhances the Angiogenic Efficacy of Adipose-Derived Stromal Cells Transplanted to Ischemic Limbs
[作者:Bhang, SH; Cho, SW; Lim, JM; Kang, JM; Lee, TJ; Yang, HS; Song, YS; Park, MH; Kim, HS; Yoo, KJ; Jang, Y; Langer, R; Anderson, DG; Kim, BS,期刊:Stem Cells, 页码:1976-1986 , 文章类型: Article,,卷期:2009年27-8]
- Ischemia is a potentially fatal medical event that is associated with as many as 30% of all deaths. Stem cell therapy offers significant therapeutic promise, but poor survival following transplantation to ischemic tissue...
- Insulin-Secreting Cells from Human Eyelid-Derived Stem Cells Alleviate Type I Diabetes in Immunocompetent Mice
[作者:Kang, HM; Kim, J; Park, S; Kim, J; Kim, H; Kim, KS; Lee, EJ; Seo, SI; Kang, SG; Lee, JE; Lim, H,期刊:Stem Cells, 页码:1999-2008 , 文章类型: Article,,卷期:2009年27-8]
- Various attempts have been made to develop stem cell-based therapy to alleviate type I diabetes using animal models. However, it has been a question whether human insulin produced from explanted cells is solely responsib...
- Initiation of Dopaminergic Differentiation of Nurr1(-) Mesencephalic Precursor Cells Depends on Activation of Multiple Mitogen-Activated Protein Kinase Pathways
[作者:Sabolek, M; Baumann, B; Heinrich, M; Meyer, AK; Herborg, A; Liebau, S; Maisel, M; Hermann, A; Ventz, K; Schwarz, J; Wirth, T; Storch, A,期刊:Stem Cells, 页码:2009-2021 , 文章类型: Article,,卷期:2009年27-8]
- Interleukin-1 (IL-1) plays a pivotal role in terminal dopaminergic differentiation of midbrain-derived neural precursor cells already committed to the mesencephalic dopaminergic phenotype (named mdNPCs for mesencephalic ...
- Epidermal Growth Factor Induces the Progeny of Subventricular Zone Type B Cells to Migrate and Differentiate into Oligodendrocytes
[作者:Gonzalez-Perez, O; Romero-Rodriguez, R; Soriano-Navarro, M; Garcia-Verdugo, JM; Alvarez-Buylla, A,期刊:Stem Cells, 页码:2032-2043 , 文章类型: Article,,卷期:2009年27-8]
- New neurons and oligodendrocytes are continuously produced in the subventricular zone (SVZ) of adult mammalian brains. Under normal conditions, the SVZ primary precursors (type B1 cells) generate type C cells, most of wh...
- Exercise Increases Neural Stem Cell Number in a Growth Hormone-Dependent Manner, Augmenting the Regenerative Response in Aged Mice
[作者:Blackmore, DG; Golmohammadi, MG; Large, B; Waters, MJ; Rietze, RL,期刊:Stem Cells, 页码:2044-2052 , 文章类型: Article,,卷期:2009年27-8]
- The exercise-induced enhancement of learning and memory, and its ability to slow age-related cognitive decline in humans led us to investigate whether running stimulates periventricular (PVR) neural stem cells (NSCs) in ...
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