- Gliosarcoma Stem Cells Undergo Glial and Mesenchymal Differentiation In Vivo
[作者:DeCarvalho, AC; Nelson, K; Lemke, N; Lehman, NL; Arbab, AS; Kalkanis, S; Mikkelsen, T,期刊:Stem Cells, 页码:181-190 , 文章类型: Article,,卷期:2010年28-2]
- Cancer stem cells (CSCs) are characterized by their self-renewing potential and by their ability to differentiate and phenocopy the original tumor in orthotopic xenografts. Long-term propagation of glioblastoma (GBM) cel...
- Heparan Sulfation-Dependent Fibroblast Growth Factor Signaling Maintains Embryonic Stem Cells Primed for Differentiation in a Heterogeneous State
[作者:Lanner, F; Lee, KL; Sohl, M; Holmborn, K; Yang, H; Wilbertz, J; Poellinger, L; Rossant, J; Farnebo, F,期刊:Stem Cells, 页码:191-200 , 文章类型: Article,,卷期:2010年28-2]
- Embryonic stem (ES) cells continuously decide whether to maintain pluripotency or differentiate. While exogenous leukemia inhibitory factor and BMP4 perpetuate a pluripotent state, less is known about the factors initiat...
- KMT1E Mediated H3K9 Methylation Is Required for the Maintenance of Embryonic Stem Cells by Repressing Trophectoderm Differentiation
[作者:Lohmann, F; Loureiro, J; Su, H; Fang, Q; Lei, H; Lewis, T; Yang, Y; Labow, M; Li, E; Chen, TP; Kadam, S,期刊:Stem Cells, 页码:201-212 , 文章类型: Article,,卷期:2010年28-2]
- Dynamic regulation of histone methylation by methyltransferases and demethylases plays a central role in regulating the fate of embryonic stem (ES) cells. The histone H3K9 methyltransferase KMT1E, formerly known as ESET ...
- Conversion of Ancestral Fibroblasts to Induced Pluripotent Stem Cells
[作者:Araki, R; Jincho, Y; Hoki, Y; Nakamura, M; Tamura, C; Ando, S; Kasama, Y; Abe, M,期刊:Stem Cells, 页码:213-220 , 文章类型: Article,,卷期:2010年28-2]
- The emergence of induced pluripotent stem cells (iPSCs) from an ancestral somatic cell is one of the most important processes underlying their generation, but the mechanism has yet to be identified. This is principally b...
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