- Glucose enhances collectrin protein expression in insulin-producing MIN6 beta cells
[作者:Saisho, K; Fukuhara, A; Yasuda, T; Sato, Y; Fukui, K; Iwahashi, H; Imagawa, A; Hatta, M; Shimomura, I; Yamagata, K,期刊:Biochemical and Biophysical Research Communications, 页码:133-137 , 文章类型: Article,,卷期:2009年389-1]
- Collectrin is a novel target gene of hepatocyte nuclear factor-1 alpha in pancreatic beta-cells and controls insulin exocytosis. Although glucose is known to stimulate the expression of genes of the insulin secretory pat...
- Chronic angiotensin-(1-7) administration improves vascular remodeling after angioplasty through the regulation of the TGF-beta/Smad signaling pathway in rabbits
[作者:Zeng, WT; Chen, WY; Leng, XY; He, JG; Ma, H,期刊:Biochemical and Biophysical Research Communications, 页码:138-144 , 文章类型: Article,,卷期:2009年389-1]
- Objective: Angiotensin-(1-7) [ANG-(1-7)] has been reported to attenuate neointimal formation after vascular injury and stent implantation in rats, but the mechanism remains mostly unresolved. Interestingly, the levels of...
- Antihypertensive and endothelium-dependent vasodilator effects of aqueous extract of Cistus ladaniferus
[作者:Belmokhtar, M; Bouanani, NE; Ziyyat, A; Mekhfi, H; Bnouham, M; Aziz, M; Mateo, P; Fischmeister, R; Legssyer, A,期刊:Biochemical and Biophysical Research Communications, 页码:145-149 , 文章类型: Article,,卷期:2009年389-1]
- Cistus ladaniferus L. (Cistaceae) is a medicinal plant originated from the Mediterranean region which exerts different pharmacological effects. In the present study, our goal was to examine whether the plant possessed an...
- Role of insulin-like growth factor-1 (IGF-1) in regulating cell cycle progression
[作者:Ma, QL; Yang, TL; Yin, JY; Peng, ZY; Yu, M; Liu, ZQ; Chen, FP,期刊:Biochemical and Biophysical Research Communications, 页码:150-155 , 文章类型: Article,,卷期:2009年389-1]
- Aims: Insulin-like growth factor-1 (IGF-1) is a polypeptide protein hormone, similar in molecular structure to insulin, which plays an important role in cell migration, cell cycle progression, cell survival and prolifera...
- Phosphorylation of ARD1 by IKK beta contributes to its destabilization and degradation
[作者:Kuo, HP; Lee, DF; Xia, WY; Lai, CC; Li, LY; Hung, MC,期刊:Biochemical and Biophysical Research Communications, 页码:156-161 , 文章类型: Article,,卷期:2009年389-1]
- I kappa B kinase beta (IKK beta), a major kinase downstream of various proinflammatory signals, mediates multiple cellular functions through phosphorylation and regulation of its substrates. On the basis of protein seque...
- Essential role of STIM1 in the development of cardiomyocyte hypertrophy
[作者:Ohba, T; Watanabe, H; Murakami, M; Sato, T; Ono, K; Ito, H,期刊:Biochemical and Biophysical Research Communications, 页码:172-176 , 文章类型: Article,,卷期:2009年389-1]
- Store-operated Ca2+ entry (SOCE) through transient receptor potential (TRP) channels is important in the development of cardiac hypertrophy. Recently, stromal interaction molecule 1 (STIM1) was identified as a key regula...
- Reduced formation of advanced glycation endproducts via interactions between glutathione peroxidase 3 and dihydroxyacetone kinase 1
[作者:Lee, H; Chi, SW; Lee, PY; Kang, S; Cho, S; Lee, CK; Bae, KH; Park, BC; Park, SG,期刊:Biochemical and Biophysical Research Communications, 页码:177-180 , 文章类型: Article,,卷期:2009年389-1]
- Dihydroxyacetone (DHA) induces the formation of advanced glycation endproducts (AGEs), which are involved in several diseases. Earlier, we identified dihydroxyacetone kinase 1 (Dak1) as a candidate glutathione peroxidase...
- Analysis of eighteen deletion breakpoints in the parkin gene
[作者:Asakawa, S; Hattori, N; Shimizu, A; Shimizu, Y; Minoshima, S; Mizuno, Y; Shimizu, N,期刊:Biochemical and Biophysical Research Communications, 页码:181-186 , 文章类型: Article,,卷期:2009年389-1]
- Parkin mutations are responsible for the pathogenesis of autosomal-recessive juvenile parkinsonism (AR-JP). On initial screening of Japanese patients with AR-JP, we had found that approximately half of the parkin mutatio...
- Regulation of vacuolar H+-ATPase in microglia by RANKL
[作者:Serrano, EM; Ricofort, RD; Zuo, J; Ochotny, N; Manolson, MF; Holliday, LS,期刊:Biochemical and Biophysical Research Communications, 页码:193-197 , 文章类型: Article,,卷期:2009年389-1]
- Vacuolar H+-ATPases (V-ATPases) are large electrogenic proton pumps composed of numerous subunits that play vital housekeeping roles in the acidification of compartments of the endocytic pathway. Additionally, V-ATPases ...
- Characterization of a novel focal adhesion kinase inhibitor in human platelets
[作者:Jones, ML; Shawe-Taylor, AJ; Williams, CM; Poole, AW,期刊:Biochemical and Biophysical Research Communications, 页码:198-203 , 文章类型: Article,,卷期:2009年389-1]
- Focal adhesion kinase (FAK) is activated in human platelets downstream of integrins, e.g. alpha(IIb)beta(3), and other adhesion receptors e. g. GPVI. Mice in which platelets lack FAK have been shown to exhibit extended b...
- Regulation of DNA topoisomerase II alpha stability by the ECV ubiquitin ligase complex
[作者:Yun, J; Kim, YI; Tomida, A; Choi, CH,期刊:Biochemical and Biophysical Research Communications, 页码:5-9 , 文章类型: Article,,卷期:2009年389-1]
- In this study, we attempted to elucidate the E3 ubiquitin ligase for topo II alpha. When cullins and VHL were ectopically expressed in HT1080 and HEK293T cells, topo II alpha was degraded most prominently in cullin 2- an...
- Novel svVEGF isoforms from Macrovipera lebetina venom interact with neuropilins
[作者:Aloui, Z; Hoos, S; Geretti, E; Kharmachi, H; Haumont, PY; Mejdoub, H; Klagsbrun, M; England, P; Gasmi, A,期刊:Biochemical and Biophysical Research Communications, 页码:10-15 , 文章类型: Article,,卷期:2009年389-1]
- Increased vascular permeability and vasodilation are responses usually elicited by snake envenomation. In this report, we isolated from Macrovipera lebetina venom two protein groups designated IC1 (Increasing Capillary1)...
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