- Effective neuropathic pain relief through sciatic nerve administration of GAD65-expressing rAAV2
[作者:Kim, J; Kim, SJ; Lee, H; Chang, JW,期刊:Biochemical and Biophysical Research Communications, 页码:73-78 , 文章类型: Article,,卷期:2009年388-1]
- Recently, we demonstrated that the administration of GAD65-expressing rAAV2 to DRG attenuates peripheral neuropathy by inducing GABA release in the spinal cord. However, the direct injection to DRG is invasive and may th...
- Functional elements in the minimal promoter of the human proton-coupled folate transporter
[作者:Stark, M; Gonen, N; Assaraf, YG,期刊:Biochemical and Biophysical Research Communications, 页码:79-85 , 文章类型: Article,,卷期:2009年388-1]
- The proton-coupled folate transporter (PCFT) is the dominant intestinal folate transporter, however, its promoter has yet to be revealed. Hence, we here cloned a 3.1 kb fragment upstream to the first ATG of the human PCF...
- NIK is involved in constitutive activation of the alternative NF-kappa B pathway and proliferation of pancreatic cancer cells
[作者:Nishina, T; Yamaguchi, N; Gohda, J; Semba, K; Inoue, J,期刊:Biochemical and Biophysical Research Communications, 页码:96-101 , 文章类型: Article,,卷期:2009年388-1]
- Pancreatic cancer has one of the poorest prognoses among human neoplasms. Constitutive activation of NF-kappa B is frequently observed in pancreatic cancer cells and is involved in their malignancy. However, little is kn...
- Involvement of PU.1 in the transcriptional regulation of TNF-alpha
[作者:Fukai, T; Nishiyama, C; Kanada, S; Nakano, N; Hara, M; Tokura, T; Ikeda, S; Ogawa, H; Okumura, K,期刊:Biochemical and Biophysical Research Communications, 页码:102-106 , 文章类型: Article,,卷期:2009年388-1]
- PU.1 is a myeloid-and lymphoid-specific transcription factor that serves many important roles in the development and specific gene regulation of hematopoietic lineages. Mast cells (MC) and dendritic cells (DC) express PU...
- Upregulation of myostatin gene expression in streptozotocin-induced type 1 diabetes mice is attenuated by insulin
[作者:Chen, YW; Cao, LZ; Ye, JW; Zhu, DH,期刊:Biochemical and Biophysical Research Communications, 页码:112-116 , 文章类型: Article,,卷期:2009年388-1]
- Myostatin is a strong inhibitor of muscle growth, and its expression is increased in several types of muscle atrophy. However, whether or not myostatin expression is altered in muscle atrophy associated with type 1 diabe...
- A role for AMPK in the inhibition of glucose-6-phosphate dehydrogenase by polyunsaturated fatty acids
[作者:Kohan, AB; Talukdar, I; Walsh, CM; Salati, LM,期刊:Biochemical and Biophysical Research Communications, 页码:117-121 , 文章类型: Article,,卷期:2009年388-1]
- Both polyunsaturated fatty acids and AMPK promote energy partitioning away from energy consuming processes, such as fatty acid synthesis, towards energy generating processes, such as beta-oxidation. In this report, we de...
- Site-specific modification of genome with cell-permeable Cre fusion protein in preimplantation mouse embryo
[作者:Kim, K; Kim, H; Lee, D,期刊:Biochemical and Biophysical Research Communications, 页码:122-126 , 文章类型: Article,,卷期:2009年388-1]
- Site-specific recombination (SSR) by Cre recombinase and its target sequence, loxP, is a valuable tool in genetic analysis of gene function. Recently, several studies reported successful application of Cre fusion protein...
- Histone methyltransferase PRDM8 regulates mouse testis steroidogenesis
[作者:Eom, GH; Kim, K; Kim, SM; Kee, HJ; Kim, JY; Jin, HM; Kim, JR; Kim, JH; Choe, N; Kim, KB; Lee, J; Kook, H; Kim, N; Seo, SB,期刊:Biochemical and Biophysical Research Communications, 页码:131-136 , 文章类型: Article,,卷期:2009年388-1]
- A family of PRDM proteins are similar to histone methyltransferases (HMTases) with SET domain in that they modulate different cellular processes, including transcriptional regulation, through chromatin modifying activiti...
- Effects of ketamine on glucose uptake by glucose transporter type 3 expressed in Xenopus oocytes: The role of protein kinase C
[作者:Tomioka, S; Kaneko, M; Satomura, K; Mikyu, T; Nakajo, N,期刊:Biochemical and Biophysical Research Communications, 页码:141-145 , 文章类型: Article,,卷期:2009年388-1]
- We investigated the effects of ketamine on the type 3 facilitative glucose transporter (GLUT3), which plays a major role in glucose transport across the plasma membrane of neurons. Human-cloned GLUT3 was expressed in Xen...
- St. John's Wort inhibits adipocyte differentiation and induces insulin resistance in adipocytes
[作者:Amini, Z; Boyd, B; Doucet, J; Ribnicky, DM; Stephens, JM,期刊:Biochemical and Biophysical Research Communications, 页码:146-149 , 文章类型: Article,,卷期:2009年388-1]
- Adipocytes are insulin sensitive cells that play a major role in energy homeostasis. Obesity is the primary disease of fat cells and a major risk factor for the development of Type II diabetes, cardiovascular disease, an...
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