- PDK1 Regulates Vascular Remodeling and Promotes Epithelial-Mesenchymal Transition in Cardiac Development
[作者:Feng, QT; Di, RM; Tao, F; Chang, Z; Lu, SS; Fan, WJ; Shan, CJ; Li, XL; Yang, ZZ,期刊:Molecular and Cellular Biology, 页码:3711-3721 , 文章类型: Article,,卷期:2010年30-14]
- One essential downstream signaling pathway of receptor tyrosine kinases (RTKs), such as vascular endothelial growth factor receptor ( VEGFR) and the Tie2 receptor, is the phosphoinositide-3 kinase (PI3K)-phosphoinositide...
- Novel Functional Residues in the Core Domain of Histone H2B Regulate Yeast Gene Expression and Silencing and Affect the Response to DNA Damage
[作者:Kyriss, MNM; Jin, Y; Gallegos, IJ; Sanford, JA; Wyrick, JJ,期刊:Molecular and Cellular Biology, 页码:3503-3518 , 文章类型: Article,,卷期:2010年30-14]
- Previous studies have identified novel modifications in the core fold domain of histone H2B, but relatively little is known about the function of these putative histone modification sites. We have mutated core modifiable...
- Functional Analysis of a Novel cis-Acting Regulatory Region within the Human Ankyrin Gene (ANK-1) Promoter
[作者:Laflamme, K; Owen, AN; Devlin, EE; Yang, MQ; Wong, C; Steiner, LA; Garrett, LJ; Elnitski, L; Gallagher, PG; Bodine, DM,期刊:Molecular and Cellular Biology, 页码:3493-3502 , 文章类型: Article,,卷期:2010年30-14]
- The characterization of atypical mutations in loci associated with diseases is a powerful tool to discover novel regulatory elements. We previously identified a dinucleotide deletion in the human ankyrin-1 gene (ANK-1) p...
- Pbx1 Represses Osteoblastogenesis by Blocking Hoxa10-Mediated Recruitment of Chromatin Remodeling Factors
[作者:Gordon, JAR; Hassan, MQ; Saini, S; Montecino, M; van Wijnen, AJ; Stein, GS; Stein, JL; Lian, JB,期刊:Molecular and Cellular Biology, 页码:3531-3541 , 文章类型: Article,,卷期:2010年30-14]
- Abdominal-class homeodomain-containing (Hox) factors form multimeric complexes with TALE-class homeodomain proteins (Pbx, Meis) to regulate tissue morphogenesis and skeletal development. Here we have established that Pbx...
- Ric-8A and Gi alpha Recruit LGN, NuMA, and Dynein to the Cell Cortex To Help Orient the Mitotic Spindle
[作者:Woodard, GE; Huang, NN; Cho, H; Miki, T; Tall, GG; Kehrl, JH,期刊:Molecular and Cellular Biology, 页码:3519-3530 , 文章类型: Article,,卷期:2010年30-14]
- In model organisms, resistance to inhibitors of cholinesterase 8 (Ric-8), a G protein alpha (G alpha) subunit guanine nucleotide exchange factor (GEF), functions to orient mitotic spindles during asymmetric cell division...
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