- Peptidoglycan Crosslinking Relaxation Promotes Helicobacter pylori's Helical Shape and Stomach Colonization
[作者：Sycuro, LK; Pincus, Z; Gutierrez, KD; Biboy, J; Stern, CA; Vollmer, W; Salama, NR,期刊：Cell, 页码：822-833 , 文章类型： Article，,卷期：2010年141-5]
- The mechanisms by which bacterial cells generate helical cell shape and its functional role are poorly understood. Helical shape of the human pathogen Helicobacter pylori may facilitate penetration of the thick gastric m...
- A Bivalent Tarantula Toxin Activates the Capsaicin Receptor, TRPV1, by Targeting the Outer Pore Domain
[作者：Bohlen, CJ; Priel, A; Zhou, S; King, D; Siemens, J; Julius, D,期刊：Cell, 页码：834-845 , 文章类型： Article，,卷期：2010年141-5]
- Toxins have evolved to target regions of membrane ion channels that underlie ligand binding, gating, or ion permeation, and have thus served as invaluable tools for probing channel structure and function. Here, we descri...
- Two Cyclin-Dependent Kinase Pathways Are Essential for Polarized Trafficking of Presynaptic Components
[作者：Ou, CY; Poon, VY; Maeder, CI; Watanabe, S; Lehrman, EK; Fu, AKY; Park, M; Fu, WY; Jorgensen, EM; Ip, NY; Shen, K,期刊：Cell, 页码：846-858 , 文章类型： Article，,卷期：2010年141-5]
- Polarized trafficking of synaptic proteins to axons and dendrites is crucial to neuronal function. Through forward genetic analysis in C. elegans, we identified a cyclin (CYY-1) and a cyclin-dependent Pctaire kinase (PCT...
- Caspase-3 Activation via Mitochondria Is Required for Long-Term Depression and AMPA Receptor Internalization
[作者：Li, Z; Jo, J; Jia, JM; Lo, SC; Whitcomb, DJ; Jiao, S; Cho, K; Sheng, M,期刊：Cell, 页码：859-871 , 文章类型： Article，,卷期：2010年141-5]
- NMDA receptor-dependent synaptic modifications, such as long-term potentiation (LTP) and long-term depression (LTD), are essential for brain development and function. LTD occurs mainly by the removal of AMPA receptors fr...
- Derivation of Pre-X Inactivation Human Embryonic Stem Cells under Physiological Oxygen Concentrations
[作者：Lengner, CJ; Gimelbrant, AA; Erwin, JA; Cheng, AW; Guenther, MG; Welstead, GG; Alagappan, R; Frampton, GM; Xu, P; Muffat, J; Santagata, S; Powers, D; Barrett, CB; Young, RA; Lee, JT; Jaenisch, R; Mitalipova, M,期刊：Cell, 页码：872-883 , 文章类型： Article，,卷期：2010年141-5]
- The presence of two active X chromosomes (XaXa) is a hallmark of the ground state of pluripotency specific to murine embryonic stem cells (ESCs). Human ESCs (hESCs) invariably exhibit signs of X chromosome inactivation (...
- Ligand-Specific c-Fos Expression Emerges from the Spatiotemporal Control of ErbB Network Dynamics
[作者：Nakakuki, T; Birtwistle, MR; Saeki, Y; Yumoto, N; Ide, K; Nagashima, T; Brusch, L; Ogunnaike, BA; Okada-Hatakeyama, M; Kholodenko, BN,期刊：Cell, 页码：884-896 , 文章类型： Article，,卷期：2010年141-5]
- Activation of ErbB receptors by epidermal growth factor (EGF) or heregulin (HRG) determines distinct cell-fate decisions, although signals propagate through shared pathways. Using mathematical modeling and experimental a...
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