- Modification of Gastric Mucin Oligosaccharide Expression in Rhesus Macaques After Infection With Helicobacter pylori
[作者:Cooke, CL; An, HJ; Kim, J; Canfield, DR; Torres, J; Lebrilla, CB; Solnick, JV,期刊:Gastroenterology, 页码:1061-1071 , 文章类型: Article,,卷期:2009年137-3]
- BACKGROUND & AIMS: Helicobacter pylori attaches to mucin oligosaccharides that are expressed on host gastric epithelium. We used the rhesus macaque model to characterize the effect of H pylori infection on gastric mucin ...
- Analysis of HLA and Non-HLA Alleles Can Identify Individuals at High Risk for Celiac Disease
[作者:Romanos, J; Van Diemen, CC; Nolte, IM; Trynka, G; Zhernakova, A; Fu, JY; Bardella, MT; Barisani, D; Mcmanus, R; Van Heel, DA; Wijmenga, C,期刊:Gastroenterology, 页码:834-840 , 文章类型: Article,,卷期:2009年137-3]
- BACKGROUND & AIMS: Celiac disease (CD) is a common chronic disorder of the small intestine, resulting from aberrant cellular responses to gluten peptides, and often remains undiagnosed. It is a complex genetic disorder, ...
- Elevated Dnmt3a Activity Promotes Polyposis in Apc(Min) Mice by Relaxing Extracellular Restraints on Wnt Signaling
[作者:Samuel, MS; Suzuki, H; Buchert, M; Putoczki, TL; Tebbutt, NC; Lundgren-May, T; Christou, A; Inglese, M; Toyota, M; Heath, JK; Ward, RL; Waring, PM; Ernst, M,期刊:Gastroenterology, 页码:902-913 , 文章类型: Article,,卷期:2009年137-3]
- BACKGROUND & AIMS: Aberrant DNA methylation is a common early event in neoplasia, but it is unclear how this relates to dysregulation of DNA (cytosine-5) methyltransferases (Dnmts). Here we use knock-in transgenic mice t...
- Endoscopic and Surgical Treatment of Mucosal (T1a) Esophageal Adenocarcinoma in Barrett's Esophagus
[作者:Prasad, GA; Wu, TT; Wigle, DA; Buttar, NS; Wongkeesong, LM; Dunagan, KT; Lutzke, LS; Borkenhagen, LS; Wang, KK,期刊:Gastroenterology, 页码:815-823 , 文章类型: Article,,卷期:2009年137-3]
- BACKGROUND & AIMS: Endoscopic therapy is emerging as an alternative to surgical therapy in patients with mucosal (T1a) esophageal adenocarcinoma (EAC) given the low likelihood of lymph node metastases. Long-term outcomes...
- Decline in Male Sexual Desire, Function, and Satisfaction During and After Antiviral Therapy for Chronic Hepatitis C
[作者:Dove, LM; Rosen, RC; Ramcharran, D; Wahed, AS; Belle, SH; Brown, RS; Hoofnagle, JH,期刊:Gastroenterology, 页码:873-884 , 文章类型: Article,,卷期:2009年137-3]
- BACKGROUND & AIMS: The recommended therapy for chronic hepatitis C, pegylated interferon and ribavirin for 24 or 48 weeks, has many known adverse side effects. The aim of this study was to evaluate the impact of antivira...
- Glucagon-Like Peptide-2 Increases Intestinal Lipid Absorption and Chylomicron Production via CD36
[作者:Hsieh, J; Longuet, C; Maida, A; Bahrami, J; Xu, E; Baker, CL; Brubaker, PL; Drucker, DJ; Adeli, K,期刊:Gastroenterology, 页码:997-1005 , 文章类型: Article,,卷期:2009年137-3]
- BACKGROUND & AIMS: Excessive postprandial lipemia is a prevalent condition that results from intestinal over-secretion of apolipoprotein B48 (apoB48)-containing lipoproteins. Glucagon-like peptide-2 (GLP-2) is a gastroin...
- ErbB Signaling Is Required for the Proliferative Actions of GLP-2 in the Murine Gut
[作者:Yusta, B; Holland, D; Koehler, JA; Maziarz, M; Estall, JL; Higgins, R; Drucker, DJ,期刊:Gastroenterology, 页码:986-996 , 文章类型: Article,,卷期:2009年137-3]
- BACKGROUND & AIMS: Glucagon-like peptide-2 (GLP-2) is a 33-amino acid peptide hormone secreted by enteroendocrine cells in response to nutrient ingestion. GLP-2 stimulates crypt cell proliferation leading to expansion of...
- Estrogen Rapidly Modulates 5-Hydroxytrytophan-Induced Visceral Hypersensitivity via GPR30 in Rats
[作者:Lu, CL; Hsieh, JC; Dun, NJ; Oprea, TI; Wang, PS; Luo, JC; Lin, HC; Chang, FY; Lee, SD,期刊:Gastroenterology, 页码:1040-1050 , 文章类型: Article,,卷期:2009年137-3]
- BACKGROUND & AIMS: Sex hormones have been reported to modulate visceral hypersensitivity (VH). Estrogen regulates neurons not only by binding to estrogen receptors (ER alpha and ER beta) to initiate transcription but als...
- Addition of Propranolol and Isosorbide Mononitrate to Endoscopic Variceal Ligation Does Not Reduce Variceal Rebleeding Incidence
[作者:Kumar, A; Jha, SK; Sharma, P; Dubey, S; Tyagi, P; Sharma, BC; Sarin, SK,期刊:Gastroenterology, 页码:892-901 , 文章类型: Article,,卷期:2009年137-3]
- BACKGROUND & AIMS: Endoscopic variceal ligation (EVL) and propranolol are standard secondary prophylaxis therapies for variceal bleeding. Addition of isosorbide monor trate (ISMN) to propranolol improves its hemodynamic ...
- Changes in Mucosal Homeostasis Predispose NHE3 Knockout Mice to Increased Susceptibility to DSS-Induced Epithelial Injury
[作者:Kiela, PR; Laubitz, D; Larmonier, CB; Midura-Kiela, MT; Lipko, MA; Janikashvili, N; Bai, A; Thurston, R; Ghishan, FK,期刊:Gastroenterology, 页码:965-975 , 文章类型: Article,,卷期:2009年137-3]
- BACKGROUND & AIMS: NHE3 is a target of inhibition by proinflammatory cytokines and pathogenic bacteria, an event contributing to diarrhea in infectious and idiopathic colitis. In mice, NHE3 deficiency leads to mild diarr...
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