- Immunoglobulin A: Fc alpha RI Interactions Induce Neutrophil Migration Through Release of Leukotriene B4
[作者:van der Steen, L; Tuk, CW; Bakema, JE; Kooij, G; Reijerkerk, A; Vidarsson, G; Bouma, G; Kraal, G; de Vries, HE; Beelen, RHJ; van Egmond, M,期刊:Gastroenterology, 页码:2018-2029 , 文章类型: Article,,卷期:2009年137-6]
- BACKGROUND & AIMS: Exacerbations of ulcerative colitis (UC) are dominated by massive neutrophil influx in the lamina propria with concomitant mucosal ulceration. The prevalent antibody in this area is immunoglobulin A (I...
- Enteropathogenic Escherichia coli Infection Inhibits Intestinal Serotonin Transporter Function and Expression
[作者:Esmaili, A; Nazir, SF; Borthakur, A; Yu, D; Turner, JR; Saksena, S; Singla, A; Hecht, GA; Alrefai, WA; Gill, RK,期刊:Gastroenterology, 页码:2074-2083 , 文章类型: Article,,卷期:2009年137-6]
- BACKGROUND & AIMS: Serotonin transporter (SERT) plays a critical role in regulating serotonin (5-hydroxy-tryptamine [5-HT]) availability in the gut. Elevated 5-HT levels are associated with diarrheal conditions such as i...
- Delayed-Release Oral Mesalamine 4.8 g/day (800-mg Tablet) Is Effective for Patients With Moderately Active Ulcerative Colitis
[作者:Sandborn, WJ; Regula, J; Feagan, BG; Belousova, E; Jojic, N; Lukas, M; Yacyshyn, B; Krzeski, P; Yeh, CH; Messer, CA; Hanauer, SB,期刊:Gastroenterology, 页码:1934-1943 , 文章类型: Article,,卷期:2009年137-6]
- BACKGROUND AND AIMS: It is not clear what induction dose of mesalamine is optimal for treating patients with mildly and moderately active ulcerative colitis (UC). This study was conducted to determine the efficacy and sa...
- Incidence of Rotavirus and All-Cause Diarrhea in Northeast Brazil Following the Introduction of a National Vaccination Program
[作者:Gurgel, RG; Bohland, AK; Vieira, SCF; Oliveira, DMP; Fontes, PB; Barros, VF; Ramos, MF; Dove, W; Nakagomi, T; Nakagomi, O; Correia, JB; Cunliffe, N; Cuevas, LE,期刊:Gastroenterology, 页码:1970-1975 , 文章类型: Article,,卷期:2009年137-6]
- BACKGROUND & AIMS: Rotavirus vaccines were introduced in Brazil in 2006; we evaluated their effects in the state of Sergipe, Brazil. METHODS: We performed a cross-sectional survey of children with diarrhea attending emer...
- Expanded Extracolonic Tumor Spectrum in MUTYH-Associated Polyposis
[作者:Vogt, S; Jones, N; Christian, D; Engel, C; Nielsen, M; Kaufmann, A; Steinke, V; Vasen, HF; Propping, P; Sampson, JR; Hes, FJ; Aretz, S,期刊:Gastroenterology, 页码:1976-1985 , 文章类型: Article,,卷期:2009年137-6]
- BACKGROUND & AIMS: MUTYH-associated polyposis (MAP) is characterized by a lifetime risk of colorectal cancer of up to 100%. However, no systematic evaluation of extracolonic manifestations has been reported. METHODS: A l...
- Expansion and Differentiation of Neural Progenitors Derived From the Human Adult Enteric Nervous System
[作者:Metzger, M; Bareiss, PM; Danker, T; Wagner, S; Hennenlotter, J; Guenther, E; Obermayr, F; Stenzl, A; Koenigsrainer, A; Skutella, T; Just, L,期刊:Gastroenterology, 页码:2063-2073 , 文章类型: Article,,卷期:2009年137-6]
- BACKGROUND & AIMS: Neural stem and progenitor cells from the enteric nervous system have been proposed for use in cell-based therapies against specific neurogastrointestinal disorders. Recently, enteric neural progenitor...
- Childhood Trauma Is Associated With Hypothalamic-Pituitary-Adrenal Axis Responsiveness in Irritable Bowel Syndrome
[作者:Videlock, EJ; Adeyemo, M; Licudine, A; Hirano, M; Ohning, G; Mayer, M; Mayer, EA; Chang, L,期刊:Gastroenterology, 页码:1954-1962 , 文章类型: Article,,卷期:2009年137-6]
- BACKGROUND & AIMS: A history of early adverse life events (EALs) is associated with a poorer outcome and higher levels of distress in adult patients with functional gastrointestinal disorders. An EAL is thought to predis...
- Psychometric Evaluation of Patient-Reported Outcomes in Irritable Bowel Syndrome Randomized Controlled Trials: A Rome Foundation Report
[作者:Spiegel, B; Camilleri, M; Bolus, R; Andresen, V; Chey, WD; Fehnel, S; Mangel, A; Talley, NJ; Whitehead, WE,期刊:Gastroenterology, 页码:1944-1953 , 文章类型: Article,,卷期:2009年137-6]
- BACKGROUND & AIMS: There is debate about how best to measure patient-reported outcomes (PROs) in irritable bowel syndrome (IBS). We pooled data to measure the psychometric properties of IBS end points, including binary r...
- Myeloid STAT3 Inhibits T Cell-Mediated Hepatitis by Regulating T Helper 1 Cytokine and Interleukin-17 Production
[作者:Lafdil, F; Wang, H; Park, O; Zhang, WC; Moritoki, Y; Yin, S; Fu, XY; Gershwin, ME; Lian, ZX; Gao, B,期刊:Gastroenterology, 页码:2125-2135 , 文章类型: Article,,卷期:2009年137-6]
- BACKGROUND & AIMS: T cell-mediated hepatitis is leading cause of acute liver failure; there is no treatment, and the mechanisms underlying its pathogenesis are obscure. The aim of this study was to investigate the immune...
- The Ion Channel TRPA1 Is Required for Normal Mechanosensation and Is Modulated by Algesic Stimuli
[作者:Brierley, SM; Hughes, PA; Page, AJ; Kwan, KY; Martin, CM; O'Donnell, TA; Cooper, NJ; Harrington, AM; Adam, B; Liebregts, T; Holtmann, G; Corey, DP; Rychkov, GY; Blackshaw, LA,期刊:Gastroenterology, 页码:2084-2095 , 文章类型: Article,,卷期:2009年137-6]
- BACKGROUND & AIMS: The transient receptor potential (TRP) channel family includes transducers of mechanical and chemical stimuli for visceral sensory neurons. TRP ankyrin I (TRPA1) is implicated in inflammatory pain; it ...
- Quantitative Perfusion Analysis of Transabdominal Contrast-Enhanced Ultrasonography of Pancreatic Masses and Carcinomas
[作者:Kersting, S; Konopke, R; Kersting, F; Volk, A; Distler, M; Bergert, H; Saeger, HD; Grutzmann, R; Bunk, A,期刊:Gastroenterology, 页码:1903-1911 , 文章类型: Article,,卷期:2009年137-6]
- BACKGROUND & AIMS: Preoperative differential diagnosis of pancreatic ductal adenocarcinoma (PDAC) and focal masses in patients with chronic pancreatitis (CP) can be challenging. There are fine differences in the vascular...
- Retinoic Acid Receptor Antagonists Inhibit miR-10a Expression and Block Metastatic Behavior of Pancreatic Cancer
[作者:Weiss, FU; Marques, IJ; Woltering, JM; Vlecken, DH; Aghdassi, A; Partecke, LI; Heidecke, CD; Lerch, MM; Bagowski, CP,期刊:Gastroenterology, 页码:2136-2145 , 文章类型: Article,,卷期:2009年137-6]
- BACKGROUND & AIMS: The infiltrating ductal adenocarcinoma of the pancreas is among the most lethal of all solid malignancies, largely owing to a high frequency of early merastasis. We identified microRNA-10a (miR-10a) as...
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