- Identification of Residues in the 558-Loop of Factor VIIIa A2 Subunit That Interact with Factor IXa
[作者:Jagannathan, I; Ichikawa, HT; Kruger, T; Fay, PJ,期刊:Journal of Biological Chemistry, 页码:32248-32255 , 文章类型: Article,,卷期:2009年284-47]
- Factor VIIIa is comprised of A1, A2, and A3C1C2 subunits. Several lines of evidence have identified the A2 558-loop as interacting with factor IXa. The contributions of individual residues within this region to inter-pro...
- Complex Phosphatase Regulation of Ca2+-activated Cl- Currents in Pulmonary Arterial Smooth Muscle Cells
[作者:Ayon, R; Sones, W; Forrest, AS; Wiwchar, M; Valencik, ML; Sanguinetti, AR; Perrino, BA; Greenwood, IA; Leblanc, N,期刊:Journal of Biological Chemistry, 页码:32507-32521 , 文章类型: Article,,卷期:2009年284-47]
- The present study was undertaken to determine whether the two ubiquitously expressed Ca2+-independent phosphatases PP1 and PP2A regulate Ca2+-activated Cl- currents (I-Cl(Ca)) elicited by 500 nM [Ca2+](i) in rabbit pulmo...
- Three-way Interaction between 14-3-3 Proteins, the N-terminal Region of Tyrosine Hydroxylase, and Negatively Charged Membranes
[作者:Halskau, O; Ying, M; Baumann, A; Kleppe, R; Rodriguez-Larrea, D; Almas, B; Haavik, J; Martinez, A,期刊:Journal of Biological Chemistry, 页码:32758-32769 , 文章类型: Article,,卷期:2009年284-47]
- Tyrosine hydroxylase (TH), the rate-limiting enzyme in the synthesis of catecholamines, is activated by phosphorylation-dependent binding to 14-3-3 proteins. The N-terminal domain of TH is also involved in interaction wi...
- Inhibition of the Equilibrative Nucleoside Transporter 1 and Activation of A(2A) Adenosine Receptors by 8-(4-Chlorophenylthio)-modified cAMP Analogs and Their Hydrolytic Products
[作者:Waidmann, O; Pleli, T; Dvorak, K; Baehr, C; Mondorf, U; Plotz, G; Biondi, RM; Zeuzem, S; Piiper, A,期刊:Journal of Biological Chemistry, 页码:32256-32263 , 文章类型: Article,,卷期:2009年284-47]
- Cyclic AMP analogs containing hydrophobic modification of C-8 at the adenine ring such as 8-(4-chlorophenylthio)-cAMP (8-pCPT-cAMP) and 8-(4-chlorophenylthio)-2'-O-methyl-cAMP (8-pCPT-2'-O-methyl-cAMP) can penetrate memb...
- Depletion of Selenoprotein GPx4 in Spermatocytes Causes Male Infertility in Mice
[作者:Imai, H; Hakkaku, N; Iwamoto, R; Suzuki, J; Suzuki, T; Tajima, Y; Konishi, K; Minami, S; Ichinose, S; Ishizaka, K; Shioda, S; Arata, S; Nishimura, M; Naito, S; Nakagawa, Y,期刊:Journal of Biological Chemistry, 页码:32522-32532 , 文章类型: Article,,卷期:2009年284-47]
- Phospholipid hydroperoxide glutathione peroxidase (GPx4) is an intracellular antioxidant enzyme that directly reduces peroxidized phospholipids. GPx4 is strongly expressed in the mitochondria of testis and spermatozoa. W...
- PGRL1 Participates in Iron-induced Remodeling of the Photosynthetic Apparatus and in Energy Metabolism in Chlamydomonas reinhardtii
[作者:Petroutsos, D; Terauchi, AM; Busch, A; Hirschmann, I; Merchant, SS; Finazzi, G; Hippler, M,期刊:Journal of Biological Chemistry, 页码:32770-32781 , 文章类型: Article,,卷期:2009年284-47]
- PGRL1 RNA and protein levels are increased in iron-deficient Chlamydomonas reinhardtii cells. In an RNAi strain, which accumulates lower PGRL1 levels in both iron-replete and -starved conditions, the photosynthetic elect...
- Bax1 Is a Novel Endonuclease IMPLICATIONS FOR ARCHAEAL NUCLEOTIDE EXCISION REPAIR
[作者:Roth, HM; Tessmer, I; Van Houten, B; Kisker, C,期刊:Journal of Biological Chemistry, 页码:32272-32278 , 文章类型: Article,,卷期:2009年284-47]
- The helicases XPB and XPD are part of the TFIIH complex, which mediates transcription initiation as well as eukaryotic nucleotide excision repair (NER). Although there is no TFIIH complex present in archaea, most species...
- Different Strategies Adopted by K-b and L-d to Generate T Cell Specificity Directed against Their Respective Bound Peptides
[作者:Bowerman, NA; Colf, LA; Garcia, KC; Kranz, DM,期刊:Journal of Biological Chemistry, 页码:32551-32561 , 文章类型: Article,,卷期:2009年284-47]
- Mouse T cell clone 2C recognizes two different major histocompatibility (MHC) ligands, the self MHC K-b and the allogeneic MHC L-d. Two distinct peptides, SIY (SIYRYYGL) and QL9 (QLSPFPFDL), act as strong and specific ag...
- Heparan Sulfate and Transglutaminase Activity Are Required for the Formation of Covalently Cross-linked Hedgehog Oligomers
[作者:Dierker, T; Dreier, R; Migone, M; Hamer, S; Grobe, K,期刊:Journal of Biological Chemistry, 页码:32562-32571 , 文章类型: Article,,卷期:2009年284-47]
- Sonic hedgehog (Shh) signaling plays major roles in embryonic development and has also been associated with the progression of certain cancers. Here, Shh family members act directly as long range morphogens, and their ab...
- Involvement of the beta Clamp in Methyl-directed Mismatch Repair in Vitro
[作者:Pluciennik, A; Burdett, V; Lukianova, O; O'Donnell, M; Modrich, P,期刊:Journal of Biological Chemistry, 页码:32782-32791 , 文章类型: Article,,卷期:2009年284-47]
- We have examined function of the bacterial beta replication clamp in the different steps of methyl-directed DNA mismatch repair. The mismatch-, MutS-, and MutL-dependent activation of MutH is unaffected by the presence o...
- Identification and Characterization of Propionylation at Histone H3 Lysine 23 in Mammalian Cells
[作者:Liu, B; Lin, YH; Darwanto, A; Song, XH; Xu, GL; Zhang, KL,期刊:Journal of Biological Chemistry, 页码:32288-32295 , 文章类型: Article,,卷期:2009年284-47]
- Propionylation has been identified recently as a new type of protein post-translational modification. Bacterial propionyl-CoA synthetase and human histone H4 are propionylated at specific lysine residues that have been k...
- Differential Involvement of Atg16L1 in Crohn Disease and Canonical Autophagy ANALYSIS OF THE ORGANIZATION OF THE Atg16L1 COMPLEX IN FIBROBLASTS
[作者:Fujita, N; Saitoh, T; Kageyama, S; Akira, S; Noda, T; Yoshimori, T,期刊:Journal of Biological Chemistry, 页码:32602-32609 , 文章类型: Article,,卷期:2009年284-47]
- A single nucleotide polymorphism in Atg16L1, an autophagy-related gene (ATG), is a risk factor for Crohn disease, a major form of chronic inflammatory bowel disease. However, it is still unknown how the Atg16L1 variant c...
- Alternative mRNA Splicing Produces a Novel Biologically Active Short Isoform of PGC-1 alpha
[作者:Zhang, YB; Huypens, P; Adamson, AW; Chang, JS; Henagan, TM; Boudreau, A; Lenard, NR; Burk, D; Klein, J; Perwitz, N; Shin, JH; Fasshauer, M; Kralli, A; Gettys, TW,期刊:Journal of Biological Chemistry, 页码:32813-32826 , 文章类型: Article,,卷期:2009年284-47]
- The transcriptional co-activator PGC-1 alpha regulates functional plasticity in adipose tissue by linking sympathetic input to the transcriptional program of adaptive thermogenesis. We report here a novel truncated form ...
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