- Endothelial colony-forming cells from patients with chronic myeloproliferative disorders lack the disease-specific molecular clonality marker
[作者:Piaggio, G; Rosti, V; Corselli, M; Bertolotti, F; Bergamaschi, G; Pozzi, S; Imperiale, D; Chiavarina, B; Bonetti, E; Novara, F; Sessarego, M; Villani, L; Garuti, A; Massa, M; Ghio, R; Campanelli, R; Bacigalupo, A; Pecci, A; Viarengo, G; Zuffardi, O; Frassoni, F; Barosi, G,期刊:Blood, 页码:3127-3130 , 文章类型: Article,,卷期:2009年114-14]
- Two putative types of circulating endothelial progenitor cells have been recently identified in vitro: (1) endothelial colony-forming cell (ECFC) and (2) colony-forming unit-endothelial cell (CFU-EC). Only the former is ...
- AML at older age: age-related gene expression profiles reveal a paradoxical down-regulation of p16(INK4A) mRNA with prognostic significance
[作者:de Jonge, HJM; de Bont, ESJM; Valk, PJM; Schuringa, JJ; Kies, M; Woolthuis, CM; Delwel, R; Veeger, NJGM; Vellenga, E; Lowenberg, B; Huls, G,期刊:Blood, 页码:2869-2877 , 文章类型: Article,,卷期:2009年114-14]
- Acute myeloid leukemia (AML) has a different clinical and biologic behavior in patients at older age. To gain further insight into the molecular differences, we examined a cohort of 525 adults to compare gene expression ...
- Donor-recipient mismatches in MHC class I chain-related gene A in unrelated donor transplantation lead to increased incidence of acute graft-versus-host disease
[作者:Parmar, S; de Lima, M; Zou, YZ; Patah, PA; Liu, P; Cano, P; Rondon, G; Pesoa, S; Silva, LD; Qazilbash, MH; Hosing, C; Popat, U; Kebriaei, P; Shpall, EJ; Giralt, S; Champlin, RE; Stastny, P; Fernandez-Vina, M,期刊:Blood, 页码:2884-2887 , 文章类型: Article,,卷期:2009年114-14]
- The polymorphic products of major histocompatibility complex class I-related chain A (MICA) genes are important in solid organ transplantation rejection. MICA expression is limited to gut epithelium and may play a role i...
- Wiskott-Aldrich syndrome protein is an effector of Kit signaling
[作者:Mani, M; Venkatasubrahmanyam, S; Sanyal, M; Levy, S; Butte, A; Weinberg, K; Jahn, T,期刊:Blood, 页码:2900-2908 , 文章类型: Article,,卷期:2009年114-14]
- The pleiotropic receptor tyrosine kinase Kit can provide cytoskeletal signals that define cell shape, positioning, and migration, but the underlying mechanisms are less well understood. In this study, we provide evidence...
- The level of monocyte turnover predicts disease progression in the macaque model of AIDS
[作者:Hasegawa, A; Liu, HN; Ling, BH; Borda, JT; Alvarez, X; Sugimoto, C; Vinet-Oliphant, H; Kim, WK; Williams, KC; Ribeiro, RM; Lackner, AA; Veazey, RS; Kuroda, MJ,期刊:Blood, 页码:2917-2925 , 文章类型: Article,,卷期:2009年114-14]
- It is widely accepted that destruction of CD4(+) T cells and viral load are the primary markers for immunodeficiency in HIV-1-infected humans and in simian immunodeficiency virus (SIV)-infected macaques. However, monocyt...
- Inhibition of histone deacetylase overcomes rapamycin-mediated resistance in diffuse large B-cell lymphoma by inhibiting Akt signaling through mTORC2
[作者:Gupta, M; Ansell, SM; Novak, AJ; Kumar, S; Kaufmann, SH; Witzig, TE,期刊:Blood, 页码:2926-2935 , 文章类型: Article,,卷期:2009年114-14]
- The mammalian target of rapamycin (mTOR) has emerged as an important therapeutic target for diffuse large B-cell lymphoma (DLBCL), as recent studies have demonstrated that 30% of relapsed patients respond to mTOR inhibit...
- Monocytes promote tumor cell survival in T-cell lymphoproliferative disorders and are impaired in their ability to differentiate into mature dendritic cells
[作者:Wilcox, RA; Wada, DA; Ziesmer, SC; Elsawa, SF; Comfere, NI; Dietz, AB; Novak, AJ; Witzig, TE; Feldman, AL; Pittelkow, MR; Ansell, SM,期刊:Blood, 页码:2936-2944 , 文章类型: Article,,卷期:2009年114-14]
- A variety of nonmalignant cells present in the tumor microenvironment promotes tumorigenesis by stimulating tumor cell growth and metastasis or suppressing host immunity. The role of such stromal cells in T-cell lymphopr...
|