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  • CLEC-2 is an essential platelet-activating receptor in hemostasis and thrombosis
    [作者:May, F; Hagedorn, I; Pleines, I; Bender, M; Vogtle, T; Eble, J; Elvers, M; Nieswandt, B,期刊:Blood, 页码:3464-3472 , 文章类型: Article,,卷期:2009年114-16]
  • Damage to the integrity of the vessel wall leads to exposure of the subendothelial extracellular matrix (ECM), triggering platelet activation and aggregation. This process is essential for primary hemostasis but it may a...
  • Cerebrovascular reserve capacity is impaired in patients with sickle cell disease
    [作者:Nur, E; Kim, YS; Truijen, J; van Beers, EJ; Davis, SCAT; Brandjes, DP; Biemond, BJ; van Lieshout, JJ,期刊:Blood, 页码:3473-3478 , 文章类型: Article,,卷期:2009年114-16]
  • Sickle cell disease (SCD) is associated with a high incidence of ischemic stroke. SCD is characterized by hemolytic anemia, resulting in reduced nitric oxide-bioavailability, and by impaired cerebrovascular hemodynamics....