- Restoration of Runx1 Expression in the Tie2 Cell Compartment Rescues Definitive Hematopoietic Stem Cells and Extends Life of Runx1 Knockout Animals Until Birth
[作者:Liakhovitskaia, A; Gribi, R; Stamateris, E; Villain, G; Jaffredo, T; Wilkie, R; Gilchrist, D; Yang, J; Ure, J; Medvinsky, A,期刊:Stem Cells, 页码:1616-1624 , 文章类型: Article,,卷期:2009年27-7]
- Mice deficient in the runt homology domain transcription factor Runx1/AML1 fail to generate functional clonogenic hematopoietic cells and die in utero by embryonic day 12.5. We previously generated Runx1 reversible knock...
- Stem Cell Therapy Restores Transparency to Defective Murine Corneas
[作者:Du, YQ; Carlson, EC; Funderburgh, ML; Birk, DE; Pearlman, E; Guo, NX; Kao, WWY; Funderburgh, JL,期刊:Stem Cells, 页码:1635-1642 , 文章类型: Article,,卷期:2009年27-7]
- Corneal scarring from trauma and inflammation disrupts vision for millions worldwide, but corneal transplantation, the primary therapy for corneal blindness, is unavailable to many affected individuals. In this study, st...
- Zinc Finger Protein 191 (ZNF191/Zfp191) Is Necessary to Maintain Neural Cells As Cycling Progenitors
[作者:Khalfallah, O; Ravassard, P; Lagache, CS; Fligny, C; Serre, A; Bayard, E; Faucon-Biguet, N; Mallet, J; Meloni, R; Nardelli, J,期刊:Stem Cells, 页码:1643-1653 , 文章类型: Article,,卷期:2009年27-7]
- The identification of the factors that allow better monitoring of stem cell renewal and differentiation is of paramount importance for the implementation of new regenerative therapies, especially with regard to the nervo...
- HOXA3 Modulates Injury-Induced Mobilization and Recruitment of Bone Marrow-Derived Cells
[作者:Mace, KA; Restivo, TE; Rinn, JL; Paquet, AC; Chang, HY; Young, DM; Boudreau, NJ,期刊:Stem Cells, 页码:1654-1665 , 文章类型: Article,,卷期:2009年27-7]
- The regulated recruitment and differentiation of multipotent bone marrow-derived cells (BMDCs) to sites of injury are critical for efficient wound healing. Previously we demonstrated that sustained expression of HOXA3 bo...
- Direct Transdifferentiation of Stem/Progenitor Spermatogonia Into Reproductive and Nonreproductive Tissues of All Germ Layers
[作者:Simon, L; Ekman, GC; Kostereva, N; Zhang, Z; Hess, RA; Hofmann, MC; Cooke, PS,期刊:Stem Cells, 页码:1666-1675 , 文章类型: Article,,卷期:2009年27-7]
- Pluripotent stem cells have great clinical potential for tissue regeneration/repair in humans. The use of embryonic stem (ES) cells is ethically controversial, leading to searches for other sources of pluripotent stem ce...
- Notch Increases T/NK Potential of Human Hematopoietic Progenitors and Inhibits B Cell Differentiation at a Pro-B Stage
[作者:Benne, C; Lelievre, JD; Balbo, M; Henry, A; Sakano, S; Levy, Y,期刊:Stem Cells, 页码:1676-1685 , 文章类型: Article,,卷期:2009年27-7]
Notch and its ligands regulate multiple cell fate decisions. However, several questions on the timing, durability, and reversibility of Notch signaling effects on human hematopoietic precursors are still unresolved. H...
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