- Biochemical characterization of GSK1070916, a potent and selective inhibitor of Aurora B and Aurora C kinases with an extremely long residence time
[作者:Anderson, K; Lai, ZH; McDonald, OB; Stuart, JD; Nartey, EN; Hardwicke, MA; Newlander, K; Dhanak, D; Adams, J; Patrick, D; Copeland, RA; Tummino, PJ; Yang, JS,期刊:Biochemical Journal, 页码:259-265 , 文章类型: Article,,卷期:2009年420-Part 2]
- The Aurora kinases AurA, B and C are serine/threonine protein kinases that play essential roles in mitosis and cytokinesis. Among them, Aura is required for maintaining proper chromosome alignment, separation and segrega...
- Dynamic interaction of hTRPC6 with the Orai1-STIM1 complex or hTRPC3 mediates its role in capacitative or non-capacitative Ca2+ entry pathways
[作者:Jardin, I; Gomez, LJ; Salido, GM; Rosado, JA,期刊:Biochemical Journal, 页码:267-276 , 文章类型: Article,,卷期:2009年420-Part 2]
- TRPC (canonical transient receptor potential) channel subunits have been shown to assemble into homo- or hetero-meric channel complexes, including different Ca2+-handling proteins, required for the activation of CCE (cap...
- Hydrogen sulfide destroys lipid hydroperoxides in oxidized LDL
[作者:Muellner, MK; Schreier, SM; Laggner, H; Hermann, M; Esterbauer, H; Exner, M; Gmeiner, BMK; Kapiotis, S,期刊:Biochemical Journal, 页码:277-281 , 文章类型: Article,,卷期:2009年420-Part 2]
- LOOHs (lipid hydroperoxides) in oxLDL oxidized LDL (low-density lipoprotein) are potentially atherogenic compounds. Recently, H2S was identified as the third endogenous gasotransmitter in the vasculature. H2O2 is known t...
- Identification of small-molecule inhibitors of the JIP-JNK interaction
[作者:Chen, T; Kablaoui, N; Little, J; Timofeevski, S; Tschantz, WR; Chen, P; Feng, JL; Charlton, M; Stanton, R; Bauer, P,期刊:Biochemical Journal, 页码:283-294 , 文章类型: Article,,卷期:2009年420-Part 2]
- JNK I (c-Jun N-terminal kinase 1) plays a crucial role ill the regulation of obesity-induced insulin resistance and is implicated ill the pathology of Type 2 diabetes. Its partner, JIP1 (JNK-interacting protein I), serve...
- Chlorella virus ATCV-1 encodes a functional potassium channel of 82 amino acids
[作者:Gazzarrini, S; Kang, M; Abenavoli, A; Romani, G; Olivari, C; Gaslini, D; Ferrara, G; Van Etten, JL; Kreim, M; Kast, SM; Thiel, G; Moroni, A,期刊:Biochemical Journal, 页码:295-303 , 文章类型: Article,,卷期:2009年420-Part 2]
- Chlorella virus PBCV-I (Paramecium bursaria chlorella virus-1) encodes the smallest protein (94 amino acids, darned Kev) previously known to form a functional K+ channel ill heterologous systems. In this paper, we charac...
|