- Dissection of Rab7 localization on Mycobacterium tuberculosis phagosome
[作者:Seto, S; Matsumoto, S; Ohta, I; Tsujimura, K; Koide, Y,期刊:Biochemical and Biophysical Research Communications, 页码:272-277 , 文章类型: Article,,卷期:2009年387-2]
- The late endosomal marker Rab7 has been long believed to be absent from the phagosome containing Mycobacterium tuberculosis (M.tb) in macrophage, but the detail kinetics remains elusive. Here, we found that Rab7 is trans...
- Mechanosensitive promoter region in the human HB-GAM gene
[作者:Liedert, A; Kassem, M; Claes, L; Ignatius, A,期刊:Biochemical and Biophysical Research Communications, 页码:289-293 , 文章类型: Article,,卷期:2009年387-2]
- Mechanical loading is essential for maintaining bone mass in the adult skeleton. However, the underlying process of the transfer of the physical stimulus into a biochemical response, which is termed mechanotransduction i...
- Acute cold exposure-induced down-regulation of CIDEA, cell death-inducing DNA fragmentation factor-alpha-like effector A, in rat interscapular brown adipose tissue by sympathetically activated beta(3)-adrenoreceptors
[作者:Shimizu, T; Yokotani, K,期刊:Biochemical and Biophysical Research Communications, 页码:294-299 , 文章类型: Article,,卷期:2009年387-2]
- The thermogenic activity of brown adipose tissue (BAT) largely depends on the mitochondrial uncoupling protein 1 (UCP1), which is up-regulated by environmental alterations such as cold. Recently, CIDEA (cell death-induci...
- Black shank resistant tobacco by silencing of glutathione S-transferase
[作者:Hernandez, I; Chacon, O; Rodriguez, R; Portieles, R; Lopez, Y; Pujol, M; Borras-Hidalgo, O,期刊:Biochemical and Biophysical Research Communications, 页码:300-304 , 文章类型: Article,,卷期:2009年387-2]
- A glutathione S-transferase gene was amplified from cDNA of Nicotiana tabacum roots infected with Phytophthora parasitica var. nicotianae. The gene was cloned in sense and anti-sense orientation to an RNAi vector for ind...
- Controlling aggregation propensity in A53T mutant of alpha-synuclein causing Parkinson's disease
[作者:Kumar, S; Sarkar, A; Sundar, D,期刊:Biochemical and Biophysical Research Communications, 页码:305-309 , 文章类型: Article,,卷期:2009年387-2]
- Understanding alpha-synuclein in terms of fibrillization, aggregation, Solubility and stability is fundamental in Parkinson's disease (PD). The three familial mutations, namely, A30P, E46K and A53T cause PD because the h...
- Ablation of phosphoinositide-3-kinase class II alpha suppresses hepatoma cell proliferation
[作者:Ng, SKL; Neo, SY; Yap, YW; Karuturi, RKM; Loh, ESL; Liau, KH; Ren, EC,期刊:Biochemical and Biophysical Research Communications, 页码:310-315 , 文章类型: Article,,卷期:2009年387-2]
- Cancer such as hepatocellular carcinoma (HCC) is characterized by complex perturbations in multiple signaling pathways, including the phosphoinositide-3-kinase (PI3K/AKT) pathways. Herein we investigated the role of PI3K...
- Ninjurin1 is expressed in myeloid cells and mediates endothelium adhesion in the brains of EAE rats
[作者:Ahn, BJ; Lee, HJ; Shin, MW; Choi, JH; Jeong, JW; Kim, KW,期刊:Biochemical and Biophysical Research Communications, 页码:321-325 , 文章类型: Article,,卷期:2009年387-2]
- Ninjurin1 (nerve injury-induced protein, Ninj1) is an adhesion molecule that is essential for cell-to-cell interactions. However. little is known about the function of Ninj1 in the central nervous system (CNS). To addres...
- Switches in 6-phosphofructo-2-kinase isoenzyme expression during rat sperm maturation
[作者:Gomez, M; Navarro-Sabate, A; Manzano, A; Duran, J; Obach, M; Bartrons, R,期刊:Biochemical and Biophysical Research Communications, 页码:330-335 , 文章类型: Article,,卷期:2009年387-2]
- Here we analyzed Pfkfb3 and Pfkfb4 gene expression in rat testis development, isolated testicular cells and spermatozoa. Real time RT-PCR analysis during testis development showed the maximum expression of Pfkfb3 in pre-...
- HDAC inhibitors, MS275 and SBHA, enhances cytotoxicity induced by oxaliplatin in the colorectal cancer cell lines
[作者:Flis, S; Gnyszka, A; Splawinski, J,期刊:Biochemical and Biophysical Research Communications, 页码:336-341 , 文章类型: Article,,卷期:2009年387-2]
- Histone deacetylases (HDACs) play an important role in the epigenetic regulation of gene expression by catalyzing the removal of acetyl groups, stimulating chromatin condensation, and promoting transcriptional repression...
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