- A General Method for the Synthesis of Unsymmetrically Substituted Ureas via Palladium-Catalyzed Amidation.
[作者:Kotecki, Brian J.;Fernando, Dilinie P.;Haight, Anthony R.;Lukin, Kirill A.;,期刊:Organic Letters, 页码:947-950 , 文章类型: 研究论文,,卷期:2009年11-4]
- A general and practical method for the prepn. of unsym. substituted ureas, e.g., I (R1 = H, Me, MeO, CN, NO2; R2 = Ph, Bn, c-hexyl, n-Bu), has been developed utilizing palladium-catalyzed amidation. Both aryl bromides a...
- Hybrid NH2-Benzimidazole Ligands for Efficient Ru-Catalyzed Asymmetric Hydrogenation of Aryl Ketones.
[作者:Li, Yuehui;Ding, Kuiling;Sandoval, Christian A.;,期刊:Organic Letters, 页码:907-910 , 文章类型: 研究论文,,卷期:2009年11-4]
- Readily available hybrid NH2/benzimidazole ligands (R-bimaH, I (R = H, Me, iPr, tBu)) dramatically influence the outcome of established Ru-based catalysts during asym. hydrogenation of aryl ketones. The benzimidazole fu...
- 6pe- versus 8pe- Electrocyclization of 1-Aryl- and Heteroaryl-Substituted (1Z,3Z)-1,3,5-Hexatrienes: A Matter of Aromaticity.
[作者:Garcia-Rubin, Silvia;Varela, Jesus A.;Castedo, Luis;Saa, Carlos;,期刊:Organic Letters, 页码:983-986 , 文章类型: 研究论文,,卷期:2009年11-4]
- Peri selectivity of the electrocyclization of 1-aryl- and heteroaryl-substituted (1Z,3Z)-1,3,5-hexatrienes, obtained by Ru-catalyzed linear coupling of 1,6-diynes to Z-propenyl(hetero)arenes, can be efficiently modulated...
- Synthesis of Amidines Using N-Allyl Ynamides. A Palladium-Catalyzed Allyl Transfer through an Ynamido-p-Allyl Complex.
[作者:Zhang, Yu;DeKorver, Kyle A.;Lohse, Andrew G.;Zhang, Yan-Shi;Huang, Jian;Hsung, Richard P.;,期刊:Organic Letters, 页码:899-902 , 文章类型: 研究论文,,卷期:2009年11-4]
- A de novo transformation of N-allyl-N-sulfonyl ynamides, e.g. I, to amidines, e.g. II, is described featuring a palladium-catalyzed N-to-C allyl transfer via ynamido-palladium-p-allyl complexes.
- The Discovery of Potent Antitumor Agent C11-Deoxypsymberin/irciniastatin A: Total Synthesis and Biology of Advanced Psymberin Analogs.
[作者:Huang, Xianhai;Shao, Ning;Huryk, Robert;Palani, Anandan;Aslanian, Robert;Seidel-Dugan, Cynthia;,期刊:Organic Letters, 页码:867-870 , 文章类型: 研究论文,,卷期:2009年11-4]
- [Image omitted] Structure-activity relationship (SAR) studies by modification of the unsatd. side chain of potent anticancer marine natural product psymberin/irciniastatin A (1) suggest that substitution at C4 and C5 is ...
- Mitsunobu approach to the synthesis of optically active a,a-disubstituted amino acids.
[作者:Green, Jonathan E.;Bender, David M.;Jackson, Stona;O'Donnell, Martin J.;McCarthy, James R.;,期刊:Organic Letters, 页码:807-810 , 文章类型: 研究论文,,卷期:2009年11-4]
- Chiral tertiary a-hydroxy esters of known stereochem. configuration were transformed to a-azido esters by Mitsunobu reaction with HN3. Optimization of this reaction was shown to proceed at room temp. with high chem. yiel...
- Stereocontrolled Synthesis of Oligoribonucleoside Phosphorothioates by an Oxazaphospholidine Approach.
[作者:Oka, Natsuhisa;Kondo, Tomoaki;Fujiwara, Satoshi;Maizuru, Yukihiro;Wada, Takeshi;,期刊:Organic Letters, 页码:967-970 , 文章类型: 研究论文,,卷期:2009年11-4]
- denaturating expts. of the resultant PS-ORNs showed that a backbone consisting of (Sp)-PS-linkages as well as stereo-random PS-linkages had an unexpectedly large destabilizing effect on a PS-ORN-ORN duplex, whereas a bac...
|