- Broadly Applicable Synthesis of 1,2,4,5-Tetraoxanes.
[作者:Ghorai, Prasanta;Dussault, Patrick H.;,期刊:Organic Letters, 页码:213-216 , 文章类型: 研究论文,,卷期:2009年11-1]
- Re2O7 is a mild and efficient catalyst for the high-yielding condensation of 1,1-dihydroperoxides with ketones or aldehydes to form 1,2,4,5-tetraoxanes, including targets not easily prepd. via existing methodol. When ap...
- Bifunctional Reactivity of CuI: Sequential Ring Opening/N-Arylation.
[作者:Martins, Andrew;Lemouzy, Sebastien;Lautens, Mark;,期刊:Organic Letters, 页码:181-183 , 文章类型: 研究论文,,卷期:2009年11-1]
- The sequential use of a single CuI catalyst enables the one-pot synthesis of N'-arylaminooxazolidinones, e.g., I, through a Lewis acid catalyzed rearrangement followed by an N-arylation reaction. Contrary to previous re...
- NHC-Catalyzed Reactions of Aryloxyacetaldehydes: A Domino Elimination/Conjugate Addition/Acylation Process for the Synthesis of Substituted Coumarins.
[作者:Phillips, Eric M.;Wadamoto, Manabu;Roth, Howard S.;Ott, Andrew W.;Scheidt, Karl A.;,期刊:Organic Letters, 页码:105-108 , 文章类型: 研究论文,,卷期:2009年11-1]
- N-Heterocyclic carbenes (NHCs) catalyze a domino Michael addn./acylation reaction to form 3,4-dihydrocoumarins, e.g. I (R = H, MeO, Me, Br, F). The reaction proceeds through addn. of the NHC to an aryloxyaldehyde follow...
- Application of Ynamides in the Synthesis of 2-Amidoindoles.
[作者:Dooleweerdt, Karin;Ruhland, Thomas;Skrydstrup, Troels;,期刊:Organic Letters, 页码:221-224 , 文章类型: 研究论文,,卷期:2009年11-1]
- A Pd-catalyzed, one-pot, two-step synthesis of 2-amidoindoles, e.g., I, from ynamides and o-iodoanilines is reported. A key highlight of this sequence is that after the Sonogashira reaction, intramol. cyclization to the...
- A Novel Synthetic Route to 3-Sulfenyl- and 3-Selenylindoles by n-Bu4NI-Induced Electrophilic Cyclization.
[作者:Chen, Yu;Cho, Chul-Hee;Larock, Richard C.;,期刊:Organic Letters, 页码:173-176 , 文章类型: 研究论文,,卷期:2009年11-1]
- 3-Sulfenyl- and 3-selenylindoles, e. g. I, are prepd. in excellent yields by the palladium/copper-catalyzed crossing coupling of N,N-dialkyl-o-iodoanilines and terminal alkynes, followed by electrophilic cyclization with...
- One-Pot Synthesis of Substituted 2,2'-Bipyrroles. A Straightforward Route to Aryl Porphycenes.
[作者:Sanchez-Garcia, David;Borrell, Jose I.;Nonell, Santi;,期刊:Organic Letters, 页码:77-79 , 文章类型: 研究论文,,卷期:2009年11-1]
- 4-MeC6H4, 4-MeOCH2C6H4, 2-naphthyl, 4-FC6H4, 4-MeOC6H4, 4-F3CC6H4, 3,5-(MeO)2C6H3, 4-pyridinyl] are prepd. in one pot from Et arylpropenoates RCH:CHCO2Et [R = Ph, 4-MeC6H4, 4-MeOCH2C6H4, 2-naphthyl, 4-FC6H4, 4-MeOC6H4, 4...
- Highly Regioselective Hydroformylation of Styrene and Its Derivatives Catalyzed by Rh Complex with Tetraphosphorus Ligands.
[作者:Yu, Shichao;Chie, Yu-ming;Guan, Zheng-hui;Zou, Yaping;Li, Wei;Zhang, Xumu;,期刊:Organic Letters, 页码:241-244 , 文章类型: 研究论文,,卷期:2009年11-1]
- Styrene has been hydroformylated to the linear aldehyde with surprisingly high regioselectivity (l/b up to 22 for styrene) using a Rh complex with a tetraphosphorus ligand. To the best of our knowledge, this is the high...
- Highly Diastereoselective Zn/SnCl2-Mediated gem-Difluoroallylation of Chiral Hydrazones.
[作者:Yue, Xuyi;Zhang, Xingang;Qing, Feng-Ling;,期刊:Organic Letters, 页码:73-76 , 文章类型: 研究论文,,卷期:2009年11-1]
- Gem-Difuoroallylic zinc reacts with chiral hydrazones, e.g. (benzylideneamino)oxazolidinone I, in the presence of SnCl2 to give versatile chiral gem-difluorohomoallylic amine building blocks, e.g. II, in good yields and ...
- Ruthenium-catalyzed synthesis of functionalized 1,3-dienes.
[作者:Achard, Mathieu;Derrien, Nolwenn;Zhang, Hui-Jun;Demerseman, Bernard;Bruneau, Christian;,期刊:Organic Letters, 页码:185-188 , 文章类型: 研究论文,,卷期:2009年11-1]
- Functionalized 1,3-diene derivs. have been prepd. by regioselective allylation of various nucleophiles with 1,3-dienic carbonates in the presence of a (N,O-carboxylate) allylruthenium precatalyst.
- Zamamidines A and B, New Manzamine Alkaloids from the Sponge Amphimedon Species.
[作者:Takahashi, Yohei;Kubota, Takaaki;Fromont, Jane;Kobayashi, Jun'ichi;,期刊:Organic Letters, 页码:21-24 , 文章类型: 研究论文,,卷期:2009年11-1]
- New manzamine alkaloids, zamamidines A (I) and B (II), have been isolated from an Okinawan marine sponge Amphimedon species. The structures and stereochem. of I and II were elucidated from the spectroscopic data and con...
- Englerin A, a Selective Inhibitor of Renal Cancer Cell Growth, from Phyllanthus engleri.
[作者:Ratnayake, Ranjala;Covell, David;Ransom, Tanya T.;Gustafson, Kirk R.;Beutler, John A.;,期刊:Organic Letters, 页码:57-60 , 文章类型: 研究论文,,卷期:2009年11-1]
- Natural product screening showed that an ext. from Phyllanthus engleri selectively inhibited the growth of renal cancer cell lines. Bioassay-guided fractionation yielded two new guaiane sesquiterpenes, englerins A (1) an...
- Antibacterial Neurymenolides from the Fijian Red Alga Neurymenia fraxinifolia.
[作者:Stout, E. Paige;Hasemeyer, Adam P.;Lane, Amy L.;Davenport, Theresa M.;Engel, Sebastian;Hay, Mark E.;Fairchild, Craig R.;Prudhomme, Jacques;Le Roch, Karine;Aalbersberg, William;Kubanek, Julia;,期刊:Organic Letters, 页码:225-228 , 文章类型: 研究论文,,卷期:2009年11-1]
- Two novel a-pyrone macrolides, neurymenolides A (I) and B (II), were isolated from the Fijian red alga Neurymenia fraxinifolia and characterized using a combination of NMR and mass spectral analyses. These mols. represe...
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