- Toll-Like Receptor Engagement Enhances the Immunosuppressive Properties of Human Bone Marrow-Derived Mesenchymal Stem Cells by Inducing Indoleamine-2,3-dioxygenase-1 via Interferon-beta and Protein Kinase R
[作者:Opitz, CA; Litzenburger, UM; Lutz, C; Lanz, TV; Tritschler, I; Koppel, A; Tolosa, E; Hoberg, M; Anderl, J; Aicher, WK; Weller, M; Wick, W; Platten, M,期刊:Stem Cells, 页码:909-919 , 文章类型: Article,,卷期:2009年27-4]
- Mesenchymal stem cells (MSC) display unique suppressive properties on T-cell immunity, thus representing an attractive vehicle for the treatment of conditions associated with harmful T-cell responses such as organ-specif...
- p27(Kip1) Constrains Proliferation of Neural Progenitor Cells in Adult Brain Under Homeostatic and Ischemic Conditions
[作者:Qiu, JH; Takagi, Y; Harada, J; Topalkara, K; Wang, YM; Sims, JR; Zheng, GG; Huang, P; Ling, Y; Scadden, DT; Moskowitz, MA; Cheng, T,期刊:Stem Cells, 页码:920-927 , 文章类型: Article,,卷期:2009年27-4]
- Cell cycle inhibition of neural stem and progenitor cells is critical for maintaining the stability of central nervous system in adults, but it may represent a significant hurdle for neural regeneration after injury. We ...
- Rostro-Caudal Gradual Loss of Cellular Diversity Within the Periventricular Regions of the Ventricular System
[作者:Hermann, A; Suess, C; Fauser, M; Kanzler, S; Witt, M; Fabel, K; Schwarz, J; Hoglinger, GU; Storch, A,期刊:Stem Cells, 页码:928-941 , 文章类型: Article,,卷期:2009年27-4]
- Neurogenesis occurs constitutively within the periventricular region (PVR) of the lateral ventricles (LV) of the adult mammalian brain. The occurrence of adult neurogenesis within the PVR outside the neurogenic niche of ...
- C/EBP beta Mediates Synergistic Upregulation of Gene Expression by Interferon-gamma and Tumor Necrosis Factor-alpha in Bone Marrow-Derived Mesenchymal Stem Cells
[作者:Xu, GW; Zhang, YY; Zhang, LY; Roberts, AI; Shi, YF,期刊:Stem Cells, 页码:942-948 , 文章类型: Article,,卷期:2009年27-4]
- Mesenchymal stem cells (MSCs) are potent immunoregulators and have shown clinical utility in suppressing immunity. MSC function is modulated by cytokines, since in. ammatory cytokines, such as interferon-gamma (IFN gamma...
- Acceleration of Skeletal Muscle Regeneration in a Rat Skeletal Muscle Injury Model by Local Injection of Human Peripheral Blood-Derived CD133-Positive Cells
[作者:Shi, M; Ishikawa, M; Kamei, N; Nakasa, T; Adachi, N; Deie, M; Asahara, T; Ochi, M,期刊:Stem Cells, 页码:949-960 , 文章类型: Article,,卷期:2009年27-4]
- Muscle injuries in sport activities can pose challenging problems in traumatology and sports medicine. The best treatment for muscle injury has not been clearly established except for the conservative treatment that is r...
- Endothelial Nitric Oxide Synthase Promotes Bone Marrow Stromal Cell Migration to the Ischemic Myocardium via Upregulation of Stromal Cell-Derived Factor-1 alpha
[作者:Li, N; Lu, XR; Zhao, XH; Xiang, FL; Xenocostas, A; Karmazyn, M; Feng, QP,期刊:Stem Cells, 页码:961-970 , 文章类型: Article,,卷期:2009年27-4]
- The aim of this study was to investigate the role of endothelial nitric oxide synthase (eNOS) in the host myocardium on bone marrow mesenchymal stromal cells (MSC) migration to the ischemic myocardium and whether stromal...
- Early Beneficial Effects of Bone Marrow-Derived Mesenchymal Stem Cells Overexpressing Akt on Cardiac Metabolism After Myocardial Infarction
[作者:Gnecchi, M; He, H; Melo, LG; Noiseaux, N; Morello, F; de Boer, RA; Zhang, L; Pratt, RE; Dzau, VJ; Ingwall, JS,期刊:Stem Cells, 页码:971-979 , 文章类型: Article,,卷期:2009年27-4]
- Administration of mesenchymal stem cells (MSCs) is an effective therapy to repair cardiac damage after myocardial infarction (MI) in experimental models. However, the mechanisms of action still need to be elucidated. Our...
- Neurosphere Formation Is an Independent Predictor of Clinical Outcome in Malignant Glioma
[作者:Laks, DR; Masterman-Smith, M; Visnyei, K; Angenieux, B; Orozco, NM; Foran, I; Yong, WH; Vinters, HV; Liau, LM; Lazareff, JA; Mischel, PS; Cloughesy, TF; Horvath, S; Kornblum, HI,期刊:Stem Cells, 页码:980-987 , 文章类型: Article,,卷期:2009年27-4]
- Renewable neurosphere formation in culture is a de. ning characteristic of certain brain tumor initiating cells. This retrospective study was designed to assess the relationship among neurosphere formation in cultured hu...
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