- Neopyrrolomycins with Broad Spectrum Antibacterial Activity
[作者:Hopp, DC; Rhea, J; Jacobsen, D; Romari, K; Smith, C; Rabenstein, J; Irigoyen, M; Clarke, M; Francis, L; Luche, M; Carr, GJ; Mocek, U,期刊:Journal of natural products, 页码:276-279 , 文章类型: Article,,卷期:2009年72-2]
- Three new antibiotics, neopyrrolomycins B (1), C (2), and D (3), with potent activity against Gram-positive pathogens were discovered. They exhibited MIC values < 1 mu g/mL versus a number of resistant strains. The compo...
- Okundoperoxide, a Bicyclic Cyclofarnesylsesquiterpene Endoperoxide from Scleria striatinux with Antiplasmodial Activity
[作者:Efange, SMN; Brun, R; Wittlin, S; Connolly, JD; Hoye, TR; McAkam, T; Makolo, FL; Mbah, JA; Nelson, DP; Nyongbela, KD; Wirmum, CK,期刊:Journal of natural products, 页码:280-283 , 文章类型: Article,,卷期:2009年72-2]
- Okundoperoxide (1) was isolated by bioassay-guided fractionation of extracts from Scleria striatinux (syn. S. striatonux). The compound contains a cyclic endoperoxide structural moiety and possesses moderate antimalarial...
- Cytotoxic Asterosaponins Capable of Promoting Polymerization of Tubulin from the Starfish Culcita novaeguineae
[作者:Tang, HF; Cheng, G; Wu, J; Chen, XL; Zhang, SY; Wen, AD; Lin, HW,期刊:Journal of natural products, 页码:284-289 , 文章类型: Article,,卷期:2009年72-2]
- Four new asterosaponins, novaeguinosides A (1), B (2), C (3), and D (4), were isolated from the bioactive fraction of the starfish Culcita novaeguineae, as active compounds capable of promoting polymerization of tubulin....
- Antiprotealide Is a Natural Product
[作者:Manam, RR; Macherla, VR; Tsueng, G; Dring, CW; Weiss, J; Neuteboom, STC; Lam, KS; Potts, BC,期刊:Journal of natural products, 页码:295-297 , 文章类型: Article,,卷期:2009年72-2]
- Large-scale fermentation of the marine actinomycete Salinispora tropica for production of salinosporamide A (NPI-0052; 1) clinical trials materials provided crude extracts containing minor secondary metabolites, includin...
- Dietary Derived Sesquiterpenes from Phyllodesmium lizardensis
[作者:Affeld, S; Kehraus, S; Wagele, H; Konig, GM,期刊:Journal of natural products, 页码:298-300 , 文章类型: Article,,卷期:2009年72-2]
- The recently discovered new aeolidean species Phyllodesmium lizardensis Burghardt, Schrodl and Wagele, 2008 was investigated concerning its secondary metabolite profile. P. lizardensis so far has only been found on Lizar...
- 3-Alkylpyridinium Alkaloids from the Pacific Sponge Haliclona sp.
[作者:Casapullo, A; Pinto, OC; Marzocco, S; Autore, G; Riccio, R,期刊:Journal of natural products, 页码:301-303 , 文章类型: Article,,卷期:2009年72-2]
- The analysis of the polar extracts of the Pacific sponge Haliclona sp. yielded new dimeric (1), trimeric (2), and polymeric 3-alkylpyridinium alkaloids. Their isolation and structural elucidation, based on NMR and MS dat...
- Alstiphyllanines A-D, Indole Alkaloids from Alstonia macrophylla
[作者:Hirasawa, Y; Arai, H; Zaima, K; Oktarina, R; Rahman, A; Ekasari, W; Widyawaruyanti, A; Indrayanto, G; Zaini, NC; Morita, H,期刊:Journal of natural products, 页码:304-307 , 文章类型: Article,,卷期:2009年72-2]
- Four new alkaloids, alstiphyllanines A-D (1-4), were isolated from Alstonia macrophylla, and their structures were determined by MS and 2D NMR analyses. Alkaloids 1-4 showed moderate antiplasmodial activity against Plasm...
- Cytotoxic Triterpenoid Alkaloids from Buxus microphylla
[作者:Yan, YX; Hu, XD; Chen, JC; Sun, Y; Zhang, XM; Qing, C; Qiu, MH,期刊:Journal of natural products, 页码:308-311 , 文章类型: Article,,卷期:2009年72-2]
- Five new triterpenoid alkaloids, buxmicrophyllines E-I (1-5), and six known ones (6-11) were isolated from the leaves and stems of Buxus microphylla. The structures of compounds 1-5 were elucidated by NMR and MS spectros...
- Piperidine and Tetrahydropyridine Alkaloids from Lobelia siphilitica and Hippobroma longiflora
[作者:Kesting, JR; Tolderlund, IL; Pedersen, AF; Witt, M; Jaroszewski, JW; Staerk, D,期刊:Journal of natural products, 页码:312-315 , 文章类型: Article,,卷期:2009年72-2]
- The hyphenated technique HPLC-PDA-MS-SPE-NMR was used to assist targeted preparative-scale isolation of constituents of Lobelia siphilitica and Hippobroma longiflora (both Campanulaceae). This resulted in the isolation o...
- Structural Revision of Stemoburkilline from an E-Alkene to a Z-Alkene
[作者:Sastraruji, K; Pyne, SG; Ung, AT; Mungkornasawakul, P; Lie, W; Jatisatienr, A,期刊:Journal of natural products, 页码:316-318 , 文章类型: Article,,卷期:2009年72-2]
- Semisynthesis studies starting from (11Z)-1',2'-didehydrostemofoline (4) indicated that the known Stemona alkaloid stemoburkilline is the Z-isomer and not the E-isomer as initially reported. The semisynthesis involved co...
- Bioactive Sulfated Sesterterpene Alkaloids and Sesterterpene Sulfates from the Marine Sponge Fasciospongia sp.
[作者:Yao, G; Kondratyuk, TP; Tan, GT; Pezzuto, JM; Chang, LC,期刊:Journal of natural products, 页码:319-323 , 文章类型: Article,,卷期:2009年72-2]
- Two new sulfated sesterterpene alkaloids, 19-oxofasciospongine A (3) and fasciospongine C (4), and a new sesterterpene sulfate, 25-hydroxyhalisulfate 9 (5), along with two known sesterterpene sulfates, halisulfates 7 (6)...
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