- CD44 engagement promotes matrix-derived survival through the CD44-Src-integrin axis in lipid rafts
[作者:Lee, JL; Wang, MJ; Sudhir, PR; Chen, JY,期刊:Molecular and Cellular Biology, 页码:5710-5723 , 文章类型: Article,,卷期:2008年28-18]
- CD44 is present in detergent-resistant, cholesterol-rich microdomains, called lipid rafts, in many types of cells. However, the functional significance of CD44 in lipid rafts is still unknown. We have previously demonstr...
- Rap1a is a key regulator of fibroblast growth factor 2-induced angiogenesis and together with Rap1b controls human endothelial cell functions
[作者:Yan, JL; Li, F; Ingram, DA; Quilliam, LA,期刊:Molecular and Cellular Biology, 页码:5803-5810 , 文章类型: Article,,卷期:2008年28-18]
- Angiogenesis, the formation of new blood vessels from existing vasculature, is regulated primarily by endothelial cell activity. We show herein that the Ras family GTPase Rap1 has a key role in the regulation of angiogen...
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