- Effects of palmitoylethanolamide on signaling pathways implicated in the development of spinal cord injury
[作者:Genovese, T; Esposito, E; Mazzon, E; Di Paola, R; Meli, R; Bramanti, P; Piomelli, D; Calignano, A; Cuzzocrea, S,期刊:Journal of Pharmacology and Experimental Therapeutics, 页码:12-23 , 文章类型: Article,,卷期:2008年326-1]
Activation of peroxisome proliferator-activated receptor (PPAR)-alpha, a member of the nuclear receptor superfamily, modulates inflammation and tissue injury events associated with spinal cord trauma in mice. Palmitoy...
- Positive modulation of GABA(B) receptors decreased nicotine self-administration and counteracted nicotine-induced enhancement of brain reward function in rats
[作者:Paterson, NE; Vlachou, S; Guery, S; Kaupmann, K; Froestl, W; Markou, A,期刊:Journal of Pharmacology and Experimental Therapeutics, 页码:306-314 , 文章类型: Article,,卷期:2008年326-1]
Acute administration of gamma-aminobutyric acid (GABA)-B receptor agonists decreases nicotine, cocaine, ethanol, and heroin self-administration and also decreases food-maintained responding and suppresses locomotor ac...
- The effect of subchronic administration of 7-(4-fluorobenzyloxy)-2,3-dimethyl-1-{[(1S,2S)-2-methylcyclopropyl]methyl}-1H-pyrrolo[2,3-d]pyridazine (CS-526), a novel acid pump antagonist, on gastric acid secretion and gastrin levels in rats
[作者:Ito, K; Kinoshita, K; Tomizawa, A; Morikawa-Inomata, Y; Inaba, F; Fujita, Y; Tabata, K; Shibakawa, N,期刊:Journal of Pharmacology and Experimental Therapeutics, 页码:163-170 , 文章类型: Article,,卷期:2008年326-1]
In the present report, we evaluated the effect of the novel acid pump antagonist 7-(4-fluorobenzyloxy)-2,3-dimethyl-1-{[(1S,2S)-2-methylcyclopropyl]methyl}-1H-pyrrolo[2,3-d]pyridazine (CS-526) and 2-[3-methyl-4-(2,2,2...
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