- Whole-genome expression profiling reveals that inhibition of host innate immune response pathways by Ebola virus can be reversed by a single amino acid change in the VP35 protein
[作者:Hartman, AL; Ling, L; Nichol, ST; Hibberd, ML,期刊:Journal of virology, 页码:5348-5358 , 文章类型: Article,,卷期:2008年82-11]
- Ebola hemorrhagic fever is a rapidly progressing acute febrile illness characterized by high virus replication, severe immunosuppression, and case fatalities of ca. 80%. Inhibition of phosphorylation of interferon regula...
- Ataxia telangiectasia-mutated damage-signaling kinase- and proteasome-dependent destruction of Mre11-Rad50-Nbs1 Subunits in simian virus 40-infected primate cells
[作者:Zhao, X; Madden-Fuentes, RJ; Lou, BX; Pipas, JM; Gerhardt, J; Rigell, CJ; Fanning, E,期刊:Journal of virology, 页码:5316-5328 , 文章类型: Article,,卷期:2008年82-11]
- Although the mechanism of simian virus 40 (SV40) DNA replication has been extensively investigated with cell extracts, viral DNA replication in productively infected cells utilizes additional viral and host functions who...
- Fusion inhibitor prevents spread of immunodeficiency viruses, but not activation of virus-specific T cells, by dendritic cells
[作者:Frank, I; Stossel, H; Gettie, A; Turville, SG; Bess, JW; Lifson, JD; Sivin, I; Romani, N; Robbiani, M,期刊:Journal of virology, 页码:5329-5339 , 文章类型: Article,,卷期:2008年82-11]
- Dendritic cells (DCs) play a key role in innate immune responses, and their interactions with T cells are critical for the induction of adaptive immunity. However, immunodeficiency viruses are efficiently captured by DCs...
- Nuclear localization sequences in cytomegalovirus capsid assembly proteins (UL80 proteins) are required for virus production: Inactivating NLS1, NLS2, or both affects replication to strikingly different extents
[作者:Nguyen, NL; Loveland, AN; Gibson, W,期刊:Journal of virology, 页码:5381-5389 , 文章类型: Article,,卷期:2008年82-11]
- Scaffolding proteins of spherical prokaryotic and eukaryotic viruses have critical roles in capsid assembly. The primary scaffolding components of cytomegalovirus, called the assembly protein precursor (pAP, pUL80.5) and...
- Proteomic analysis of pathogenic and attenuated alcelaphine herpesvirus 1
[作者:Dry, I; Haig, DM; Inglis, NF; Imrie, L; Stewart, JP; Russell, GC,期刊:Journal of virology, 页码:5390-5397 , 文章类型: Article,,卷期:2008年82-11]
- The gammaherpesvirus alcelaphine herpesvirus 1 (A1HV-1) causes malignant catarrhal fever in susceptible ungulates but infects its natural host, wildebeest, without obvious clinical signs. In tissue culture, AlHV-1 is ini...
- Structural and functional constraints limit options for cytotoxic T-lymphocyte escape in the immunodominant HLA-B27-restricted epitope in human immunodeficiency virus type 1 capsid
[作者:Schneidewind, A; Brockman, MA; Sidney, J; Wang, YYE; Chen, HB; Suscovich, TJ; Li, B; Adam, RI; Allgaier, RL; Mothe, BR; Kuntzen, T; Oniangue-Ndza, C; Trocha, A; Yu, XG; Brander, C; Sette, A; Walker, BD; Allen, TM,期刊:Journal of virology, 页码:5594-5605 , 文章类型: Article,,卷期:2008年82-11]
- Control of human immunodeficiency virus type 1 (HIV-1) by HLA-B27-positive subjects has been linked to an immunodominant CD8(+) cytotoxic T-lymphocyte (CTL) response targeting the conserved KK10 epitope (KRWIILGLNK(263-2...
- Anticapsid immunity level, not viral persistence level, correlates with the progression of Theiler's virus-induced demyelinating disease in viral P1-transgenic mice
[作者:Myoung, JJ; Bahk, YY; Kang, HS; Dal Canto, MC; Kim, BS,期刊:Journal of virology, 页码:5606-5617 , 文章类型: Article,,卷期:2008年82-11]
- Intracranial infection of Theiler's murine encephalomyelitis virus (TMEV) induces demyelination and a neurological disease in susceptible SJL/J (SJL) mice that resembles multiple sclerosis. While the virus is cleared fro...
- Increased loss of CCR5(+) CD45RA(-) CD4(+) T cells in CD8(+) lymphocyte-depleted simian immunodeficiency virus-infected rhesus monkeys
[作者:Veazey, RS; Acierno, PM; McEvers, KJ; Baumeister, SHC; Foster, GJ; Rett, MD; Newberg, MH; Kuroda, MJ; Williams, K; Kim, EY; Wolinsky, SM; Rieber, EP; Piatak, M; Lifson, JD; Montefiori, DC; Brown, CR; Hirsch, VA; Schmitz, JE,期刊:Journal of virology, 页码:5618-5630 , 文章类型: Article,,卷期:2008年82-11]
- Previously we have shown that CD8(+) T cells are critical for containment of simian immunodeficiency virus (SIV) viremia and that rapid and profound depletion of CD4(+) T cells occurs in the intestinal tract of acutely i...
- Contribution of CD8(+) T cells to containment of viral replication and emergence of mutations in Mamu-A*01-restricted epitopes in simian immunodeficiency virus-infected rhesus monkeys
[作者:Kim, EY; Veazey, RS; Zahn, R; McEvers, KJ; Baumeister, SHC; Foster, GJ; Rett, MD; Newberg, MH; Kuroda, MJ; Rieber, EP; Piatak, M; Lifson, JD; Letvin, NL; Wolinsky, SM; Schmitz, JE,期刊:Journal of virology, 页码:5631-5635 , 文章类型: Article,,卷期:2008年82-11]
- Here, we investigated the containment of virus replication in simian immunodeficiency virus (SIV) infection by CD8(+) lymphocytes. Escape mutations in Mamu-A*01 epitopes appeared first in SIV Tat TL8 and then in SIV Gag ...
- Comparison of cellular ribonucleoprotein complexes associated with the APOBEC3F and APOBEC3G antiviral proteins
[作者:Gallois-Montbrun, S; Holmes, RK; Swanson, CM; Fernandez-Ocana, M; Byers, HL; Ward, MA; Malim, MH,期刊:Journal of virology, 页码:5636-5642 , 文章类型: Article,,卷期:2008年82-11]
- The human apolipoprotein B mRNA-editing enzyme catalytic polypeptide-like 3F (APOBEC3F [A3F]) and A3G proteins are effective inhibitors of infection by various retroelements and share similar to 50% amino acid sequence i...
- Recruitment of antigen-presenting cells to the site of inoculation and augmentation of human immunodeficiency virus type 1 DNA vaccine immunogenicity by in vivo Electroporation
[作者:Liu, JY; Kjeken, R; Mathiesen, L; Barouch, DH,期刊:Journal of virology, 页码:5643-5649 , 文章类型: Article,,卷期:2008年82-11]
- In vivo electroporation (EP) has been shown to augment the immunogenicity of plasmid DNA vaccines, but its mechanism of action has not been fully characterized. In this study, we show that in vivo EP augmented cellular a...
- High temperature (30 degrees C) blocks aerosol but not contact transmission of influenza virus
[作者:Lowen, AC; Steel, J; Mubareka, S; Palese, P,期刊:Journal of virology, 页码:5650-5652 , 文章类型: Article,,卷期:2008年82-11]
- Influenza causes significant morbidity in tropical regions; however, unlike in temperate zones, influenza in the tropics is not strongly associated with a given season. We have recently shown that influenza virus transmi...
- Different mutational pathways to CXCR4 coreceptor switch of CCR5-using simian-human immunodeficiency virus
[作者:Ho, SH; Trunova, N; Gettie, A; Blanchard, J; Cheng-Mayer, C,期刊:Journal of virology, 页码:5653-5656 , 文章类型: Article,,卷期:2008年82-11]
- We report here a second case of coreceptor switch in R5 simian-human immunodeficiency virus SF162P3N (SHIVSF162P3N) -infected macaque CA28, supporting the use of this experimental system to examine factors that drive the...
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