- The Immune Evasion Paradox: Immunoevasins of Murine Cytomegalovirus Enhance Priming of CD8 T Cells by Preventing Negative Feedback Regulation-
[作者:Bohm, V; Simon, CO; Podlech, J; Seckert, CK; Gendig, D; Deegen, P; Gillert-Marien, D; Lemmermann, NAW; Holtappels, R; Reddehase, MJ,期刊:Journal of virology, 页码:11637-11650 , 文章类型: Article,,卷期:2008年82-23]
- Cytomegaloviruses express glycoproteins that interfere with antigen presentation to CD8 T cells. Although the molecular modes of action of these "immunoevasins" differ between cytomegalovirus species, the convergent biol...
- Profiling the Specificity of Neutralizing Antibodies in a Large Panel of Plasmas from Patients Chronically Infected with Human Immunodeficiency Virus Type 1 Subtypes B and C
[作者:Binley, JM; Lybarger, EA; Crooks, ET; Seaman, MS; Gray, E; Davis, KL; Decker, JM; Wycuff, D; Harris, L; Hawkins, N; Wood, B; Nathe, C; Richman, D; Tomaras, GD; Bibollet-Ruche, F; Robinson, JE; Morris, L; Shaw, GM; Montefiori, DC; Mascola, JR,期刊:Journal of virology, 页码:11651-11668 , 文章类型: Article,,卷期:2008年82-23]
- Identifying the viral epitopes targeted by broad neutralizing antibodies (NAbs) that sometimes develop in human immunodeficiency virus type 1 (HIV-1)-infected subjects should assist in the design of vaccines to elicit si...
- Biochemical and Biophysical Characterization of a Chimeric TRIM21-TRIM5 alpha Protein
[作者:Kar, AK; Diaz-Griffero, F; Li, Y; Li, X; Sodroski, J,期刊:Journal of virology, 页码:11669-11681 , 文章类型: Article,,卷期:2008年82-23]
- The tripartite motif (TRIM) protein, TRIM5 alpha, is an endogenous factor in primates that recognizes the capsids of certain retroviruses after virus entry into the host cell. TRIM5 alpha promotes premature uncoating of ...
- Biochemical Characterization of a Recombinant TRIM5 alpha Protein That Restricts Human Immunodeficiency Virus Type 1 Replication
[作者:Langelier, CR; Sandrin, V; Eckert, DM; Christensen, DE; Chandrasekaran, V; Alam, SL; Aiken, C; Olsen, JC; Kar, AK; Sodroski, JG; Sundquist, WI,期刊:Journal of virology, 页码:11682-11694 , 文章类型: Article,,卷期:2008年82-23]
- The rhesus monkey intrinsic immunity factor TRIM5 alpha(rh) recognizes incoming capsids from a variety of retroviruses, including human immunodeficiency virus type 1 (HIV-1) and equine infectious anemia virus (EIAV), and...
- Baseline Resistance of Primary Human Immunodeficiency Virus Type 1 Strains to the CXCR4 Inhibitor AMD3100
[作者:Harrison, JE; Lynch, JB; Sierra, LJ; Blackburn, LA; Ray, N; Collman, RG; Doms, RW,期刊:Journal of virology, 页码:11695-11704 , 文章类型: Article,,卷期:2008年82-23]
- We screened a panel of R5X4 and X4 human immunodeficiency virus type 1 (HIV-1) strains for their sensitivities to AMD3100, a small-molecule CXCR4 antagonist that blocks HIV-1 infection via this coreceptor. While no longe...
- Clearance of Adenovirus by Kupffer Cells Is Mediated by Scavenger Receptors, Natural Antibodies, and Complement
[作者:Xu, ZL; Tian, J; Smith, JS; Byrnes, AP,期刊:Journal of virology, 页码:11705-11713 , 文章类型: Article,,卷期:2008年82-23]
- Kupffer cells (KCs) rapidly remove intravenously injected adenovirus (Ad) vectors from the circulation. A better understanding of the mechanisms involved could suggest strategies to improve Ad gene delivery by suppressin...
- Lymphocytic Choriomeningitis Virus Infection Yields Overlapping CD4(+) and CD8(+) T-Cell Responses
[作者:Dow, C; Oseroff, C; Peters, B; Nance-Sotelo, C; Sidney, J; Buchmeier, M; Sette, A; Mothe, BR,期刊:Journal of virology, 页码:11734-11741 , 文章类型: Article,,卷期:2008年82-23]
- Activation of CD4(+) T cells helps establish and sustain other immune responses. We have previously shown that responses against a broad set of nine CD4(+) T-cell epitopes were present in the setting of lymphocytic chori...
- Mutational Analysis of cis-Acting RNA Signals in Segment 7 of Influenza A Virus
[作者:Hutchinson, EC; Curran, MD; Read, EK; Gog, JR; Digard, P,期刊:Journal of virology, 页码:11869-11879 , 文章类型: Article,,卷期:2008年82-23]
- The genomic viral RNA (vRNA) segments of influenza A virus contain specific packaging signals at their termini that overlap the coding regions. To further characterize cis-acting signals in segment 7, we introduced synon...
- Evolution of CCR5 Use before and during Coreceptor Switching
[作者:Coetzer, M; Nedellec, R; Salkowitz, J; McLaughlin, S; Liu, Y; Heath, L; Mullins, JI; Mosier, DE,期刊:Journal of virology, 页码:11758-11766 , 文章类型: Article,,卷期:2008年82-23]
- The envelope gene (env) of human immunodeficiency virus type 1 (HIV-1) undergoes rapid divergence from the transmitted sequence and increasing diversification during the prolonged course of chronic infection in humans. I...
- Role of Cellular Glycosaminoglycans and Charged Regions of Viral G Protein in Human Metapneumovirus Infection
[作者:Thammawat, S; Sadlon, TA; Hallsworth, PG; Gordon, DL,期刊:Journal of virology, 页码:11767-11774 , 文章类型: Article,,卷期:2008年82-23]
- Human metapneumovirus (hMPV) is an important cause of lower respiratory tract disease, particularly in infants and young children. hMPV has two major glycoproteins, G and F, which are responsible for virus attachment and...
- Compatibility among Polymerase Subunit Proteins Is a Restricting Factor in Reassortment between Equine H7N7 and Human H3N2 Influenza Viruses
[作者:Li, CJ; Hatta, M; Watanabe, S; Neumann, G; Kawaoka, Y,期刊:Journal of virology, 页码:11880-11888 , 文章类型: Article,,卷期:2008年82-23]
- Reassortment is an important driving force for influenza virus evolution, and a better understanding of the factors that affect this process could improve our ability to respond to future influenza pandemics and epidemic...
- Equine Infectious Anemia Virus Resists the Antiretroviral Activity of Equine APOBEC3 Proteins through a Packaging-Independent Mechanism
[作者:Bogerd, HP; Tallmadge, RL; Oaks, JL; Carpenter, S; Cullen, BR,期刊:Journal of virology, 页码:11889-11901 , 文章类型: Article,,卷期:2008年82-23]
- Equine infectious anemia virus (EIAV), uniquely among lentiviruses, does not encode a vif gene product. Other lentiviruses, including human immunodeficiency virus type 1 (HIV-1), use Vif to neutralize members of the APOB...
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