- Ascitic fluid lactoferrin for diagnosis of spontaneous bacterial peritonitis
[作者:Parsi, MA; Saadeh, SN; Zein, NN; Davis, GL; Lopez, R; Boone, J; Lepe, MR; Guo, LS; Ashfaq, M; Klintmalm, G; McCullough, AJ,期刊:Gastroenterology, 页码:803-807 , 文章类型: Article,,卷期:2008年135-3]
- Background & Aim: The diagnosis of spontaneous bacterial peritonitis (SBP) is based on a manual count of ascitic fluid polymorphonuclear cells (PMNs). This procedure is operator-dependent and lysis of PMNs during transpo...
- TIPS for Budd-Chiari syndrome: Long-term results and prognostics factors in 124 patients
[作者:Garcia-Pagan, JC; Heydtmann, M; Raffa, S; Plessier, A; Murad, S; Fabris, F; Vizzini, G; Abraldes, JG; Olliff, S; Nicolini, A; Luca, A; Primignani, M; Janssen, HLA; Valla, D; Elias, E; Bosch, J,期刊:Gastroenterology, 页码:808-815 , 文章类型: Article,,卷期:2008年135-3]
- Background & Aims: Budd-Chiari syndrome (BCS) is a rare and life-threatening disorder secondary to hepatic venous outflow obstruction. Small series of BCS patients indicate that transjugular intrahepatic portosystemic sh...
- Eradication of hepatitis C virus in patients successfully treated for chronic hepatitis C
[作者:Maylin, S; Martinot-Peignoux, M; Moucari, R; Boyer, N; Ripault, MP; Cazals-Hatem, D; Giuily, N; Castelnau, C; Cardoso, AC; Asselah, T; Feray, C; Nicolas-Chanoine, MH; Bedossa, P; Marcellin, P,期刊:Gastroenterology, 页码:821-829 , 文章类型: Article,,卷期:2008年135-3]
- Background & Aims: It is unclear whether hepatitis C virus (HCV) is eradicated in patients with chronic hepatitis C who achieved a sustained virologic response (SVR). Methods: In this long-term follow-up study, including...
- Androgen receptor is a new potential therapeutic target for the treatment of hepatocellular carcinoma
[作者:Ma, CL; Hsu, CL; Wu, MH; Wu, CT; Wu, CC; Lai, JJ; Jou, YS; Chen, CW; Yeh, SY; Chang, CS,期刊:Gastroenterology, 页码:947-955 , 文章类型: Article,,卷期:2008年135-3]
- Background & Aims: Androgen effects on hepatocellular carcinoma (HCC) remain controversial and androgen ablation therapy to treat HCC also leads to inconsistent results. Here we examine androgen receptor (AR) roles in he...
- Down-regulation of osteopontin suppresses growth and metastasis of hepatocellular carcinoma via induction of apoptosis
[作者:Zhao, J; Dong, L; Liu, B; Wu, GB; Xu, DM; Chen, JJ; Li, K; Tong, X; Dai, JX; Yao, S; Wu, MC; Guo, YJ,期刊:Gastroenterology, 页码:956-968 , 文章类型: Article,,卷期:2008年135-3]
- Background & Aims: Expression of osteopontin correlates with tumor progression and metastasis. The mechanisms by which osteopontin promotes tumor cell survival remain unclear. Here we used short-hairpin RNA-mediated gene...
- B7-H1 on hepatocytes facilitates priming of specific CD8 T cells but limits the specific recall of primed responses
[作者:Wahl, C; Bochtler, P; Chen, LP; Schirmbeck, R; Reimann, J,期刊:Gastroenterology, 页码:980-988 , 文章类型: Article,,卷期:2008年135-3]
- Background & Aims: The requirement for costimulation of CD8 T-cell priming and restimulation by nonprofessional antigen-presenting cells is unresolved. Here, we investigated whether B7-H1 (CD274, PD-L1) on hepatocytes (H...
- Intrahepatic murine CD8 T-Cell activation associates with a distinct phenotype leading to Bim-dependent death
[作者:Holz, LE; Benseler, V; Bowen, DG; Bouillet, P; Strasser, A; O'Reilly, L; D'Avigdor, WMH; Bishop, AG; McCaughan, GW; Bertolino, P,期刊:Gastroenterology, 页码:989-997 , 文章类型: Article,,卷期:2008年135-3]
- Background & Aims: Chronic infections by hepatotropic viruses such as hepatitis B and C are generally associated with an impaired CD8 T-cell immune response that is unable to clear the virus. The liver is increasingly re...
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