- The colorful history of active DNA demethylation
[作者:Ooi, SKT; Bestor, TH,期刊:Cell, 页码:1145-1148 , 文章类型: News Item,,卷期:2008年133-7]
- Patterns of DNA cytosine methylation are subject to mitotic inheritance in both plants and vertebrates. Plants use 5-methylcytosine glycosylases and the base excision repair pathway to remove excess cytosine methylation....
- A lexicon for homeodomain-DNA recognition
[作者:Affolter, M; Slattery, M; Mann, RS,期刊:Cell, 页码:1133-1135 , 文章类型: News Item,,卷期:2008年133-7]
- Decoding the cis-regulatory logic of eukaryotic genomes requires knowledge of the DNA-binding specificities of all transcription factors. New work (Berger et al., 2008; Noyes et al., 2008) provides individual specificiti...
- Molecular movies ... Coming to a lecture near you
[作者:McGill, G,期刊:Cell, 页码:1127-1132 , 文章类型: News Item,,卷期:2008年133-7]
- Scientific visualizations are powerful tools for communicating the intricacies of cellular and molecular structures and dynamics. There is a disconnect, however, between the research data sets we seek to represent and th...
- Forging new ties between E-coli genes
[作者:Ideker, T,期刊:Cell, 页码:1135-1137 , 文章类型: News Item,,卷期:2008年133-7]
- A recent study in Nature (Isalan et al., 2008) has examined the effects of systematically adding new transcriptional interactions in the bacterium Escherichia coli. Surprisingly, the majority of the engineered connection...
- LUSH shapes up for a starring role in olfaction
[作者:Stowers, L; Logan, DW,期刊:Cell, 页码:1137-1139 , 文章类型: News Item,,卷期:2008年133-7]
- In the fruit fly Drosophila, odorant-binding proteins are secreted into the fluid that bathes olfactory neurons. Laughlin et al. (2008) now challenge the assumption that the odorant-binding protein LUSH passively transpo...
- Hedgehog nanopackages ready for dispatch
[作者:Vincent, JP,期刊:Cell, 页码:1139-1141 , 文章类型: News Item,,卷期:2008年133-7]
- Hedgehog proteins are intercellular long-range signaling molecules that spread within tissues and activate gene expression during development. Vyas et al. (2008) propose that Hedgehog forms nanometer-sized oligomers that...
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