- A histone code for chromatin assembly
[作者：Fillingham, J; Greenblatt, JF,期刊：Cell, 页码：206-208 , 文章类型： Article，,卷期：2008年134-2]
- In this issue, two papers implicate histone H3 lysine 56 acetylation in histone deposition in chromatin. Li et al. ( 2008) show that acetylation of H3K56 promotes S phase chromatin assembly that is mediated by the histon...
- A PASport to cellular proliferation
[作者：Zlotorynski, E; Agami, R,期刊：Cell, 页码：208-210 , 文章类型： Article，,卷期：2008年134-2]
- The use of alternative polyadenylation sites produces mRNA isoforms with different 3' untranslated regions. A recent report in Science (Sandberg et al., 2008) suggests that alternative polyadenylation is connected to mic...
- Cdc14B and APC/C tackle DNA damage
[作者：De Wulf, P; Visintin, R,期刊：Cell, 页码：210-212 , 文章类型： Article，,卷期：2008年134-2]
- Mitotic exit in budding yeast is regulated by the proteins Cdc14, APC/C-Cdh1, and Plk1. In this issue, Bassermann and colleagues (2008) show that this network of proteins has been rewired in human cells to control the ce...
- Acetylated lysine 56 on histone H3 drives chromatin assembly after repair and signals for the completion of repair
[作者：Chen, CC; Carson, JJ; Feser, J; Tamburini, B; Zabaronick, S; Linger, J; Tyler, JK,期刊：Cell, 页码：231-243 , 文章类型： Article，,卷期：2008年134-2]
- DNA damage causes checkpoint activation leading to cell cycle arrest and repair, during which the chromatin structure is disrupted. The mechanisms whereby chromatin structure and cell cycle progression are restored after...
- SIRT1 is a circadian deacetylase for core clock components
[作者：Belden, WJ; Dunlap, JC,期刊：Cell, 页码：212-214 , 文章类型： Article，,卷期：2008年134-2]
- The transcriptional activator CLOCK is a histone acetyltransferase that is required for the circadian expression of many genes. Asher et al. (2008) and Nakahata et al. (2008) now demonstrate that the NAD(+)-dependent enz...
- Acetylation of histone H3 lysine 56 regulates replication-coupled nucleosome assembly
[作者：Li, Q; Zhou, H; Wurtele, H; Davies, B; Horazdovsky, B; Verreault, A; Zhang, ZG,期刊：Cell, 页码：244-255 , 文章类型： Article，,卷期：2008年134-2]
- Chromatin assembly factor 1 (CAF-1) and Rtt106 participate in the deposition of newly synthesized histones onto replicating DNA to form nucleosomes. This process is critical for the maintenance of genome stability and in...
- Structural insights into E1-catalyzed ubiquitin activation and transfer to conjugating enzymes
[作者：Lee, I; Schindelin, H,期刊：Cell, 页码：268-278 , 文章类型： Article，,卷期：2008年134-2]
- Ubiquitin (Ub) and ubiquitin-like proteins (Ubls) are conjugated to their targets by specific cascades involving three classes of enzymes, E1, E2, and E3. Each E1 adenylates the C terminus of its cognate Ubl, forms a E1 ...
- The Cdc14B-Cdh1-Plk1 axis controls the G2 DNA-damage-response checkpoint
[作者：Bassermann, F; Frescas, D; Guardavaccaro, D; Busino, L; Peschiaroli, A; Pagano, M,期刊：Cell, 页码：256-267 , 文章类型： Article，,卷期：2008年134-2]
- In response to DNA damage in G2, mammalian cells must avoid entry into mitosis and instead initiate DNA repair. Here, we show that, in response to genotoxic stress in G2, the phosphatase Cdc14B translocates from the nucl...
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