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  • A Charged Performance by gp17 in Viral Packaging
    [作者:Williams, RS; Williams, GJ; Tainer, JA,期刊:Cell, 页码:1169-1171 , 文章类型: Editorial Material,,卷期:2008年135-7]
  • Packaging of viral genomes into virus capsids requires powerful motors to overcome the repulsive force that builds as the nucleic acids are compressed. Through structural analyses of the T4 bacteriophage packaging motor ...
  • Mitofusin 2 Builds a Bridge between ER and Mitochondria
    [作者:Merkwirth, C; Langer, T,期刊:Cell, 页码:1165-1167 , 文章类型: Editorial Material,,卷期:2008年135-7]
  • Mutations in mitofusin 2 (MFN2), a dynamin-like GTPase required for mitochondrial fusion, cause the peripheral neuropathy Charcot-Marie-Tooth type 2A. In a recent report in Nature, de Brito and Scorrano (2008) demonstrat...
  • Here Comes the Sun: Recognition of UV-Damaged DNA
    [作者:Chu, G; Yang, W,期刊:Cell, 页码:1172-1174 , 文章类型: Editorial Material,,卷期:2008年135-7]
  • The first step in the repair of DNA damage is lesion detection. In this issue, Scrima et al. (2008) report the structure of the complex of DNA Damage-Binding Protein 1 (DDB1) and DDB2 bound to a DNA photodimer, providing...
  • Tracing the Retrograde Route in Protein Trafficking
    [作者:Johannes, L; Popoff, V,期刊:Cell, 页码:1175-1187 , 文章类型: Review,,卷期:2008年135-7]
  • Retrograde transport, in which proteins and lipids are shuttled between endosomes and biosynthetic/secretory compartments such as the Golgi apparatus, is crucial for a diverse range of cellular functions. Mechanistic stu...