- Marine natural product libraries for high-throughput screening and rapid drug discovery
[作者:Bugni, TS; Richards, B; Bhoite, L; Cimbora, D; Harper, MK; Ireland, CM,期刊:Journal of natural products, 页码:1095-1098 , 文章类型: Article,,卷期:2008年71-6]
- There is a need for diverse molecular libraries for phenotype-selective and high-throughput screening. To make marine natural products (MNPs) more amenable to newer screening paradigms and shorten discovery time lines, w...
- Nigellidine-4-O-sulfite, the first sulfated indazole-type alkaloid from the seeds of Nigella sativa
[作者:Ali, Z; Ferreira, D; Carvalho, P; Avery, MA; Khan, IA,期刊:Journal of natural products, 页码:1111-1112 , 文章类型: Article,,卷期:2008年71-6]
- The rare indazole-type alkaloid nigellidine (2) is accompanied by its 4-0-sulfite (4) in the seeds of Nigella sativa. Compound 4 may represent the true natural product leading to nigellidine (2) via hydrolysis of the sul...
- Apratoxin D, a potent cytotoxic cyclodepsipeptide from Papua New Guinea collections of the marine cyanobacteria Lyngbya majuscula and Lyngbya sordida
[作者:Gutierrez, M; Suyama, TL; Engene, N; Wingerd, JS; Matainaho, T; Gerwick, WH,期刊:Journal of natural products, 页码:1099-1103 , 文章类型: Article,,卷期:2008年71-6]
- Cancer cell toxicity-guided fractionation of extracts of the Papua New Guinea marine cyanobacteria Lyngbya majuscula and Lyngbya sordida led to the isolation of apratoxin D (1). Compound I contains the same macrocycle as...
- A cycloartane incorporating a fused tetrahydrofuran ring and a cytotoxic lactam from Monocarpia marginalis
[作者:Lim, SH; Mahmood, K; Komiyama, K; Kam, TS,期刊:Journal of natural products, 页码:1104-1106 , 文章类型: Article,,卷期:2008年71-6]
- A new cycloartane, monocarpinine (1), incorporating a fused tetrahydrofuranyl ring, and a cytotoxic tetracyclic lactam, monomarginine (2), were isolated from a stem bark extract of the Malayan species Monocarpia marginal...
- Antitussive stemoninine alkaloids from the roots of Stemona tuberosa
[作者:Lin, LG; Li, KM; Tang, CP; Ke, CQ; Rudd, JA; Lin, G; Ye, Y,期刊:Journal of natural products, 页码:1107-1110 , 文章类型: Article,,卷期:2008年71-6]
- Investigation of the roots of Stemona tuberosa afforded five minor constituents, stemoenonine (1), 9a-0-methylstemoenonine (2), oxystemoenonine (3), 1,9a-seco-stemoenonine (4), and oxystemoninine (5), along with the know...
- Cannabinoid ester constituents from high-potency Cannabis sativa (vol 71, pg 536, 2008)
[作者:Ahmed, SA; Ross, SA; Slade, D; Radwan, MM; Zulfiqar, F; Matsumoto, RR; Xu, YT; Viard, E; Speth, RC; Karamyan, VT; ElSohly, MA,期刊:Journal of natural products, 页码:1119-1119 , 文章类型: Correction,,卷期:2008年71-6]
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- NF-kappa B inhibiting naphthopyrones from the fijian echinoderm Comanthus parvicirrus (vol 71, pg 106, 2008)
[作者:Folmer, F; Harrison, WTA; Tabudravu, JN; Jaspars, M; Aalbersberg, W; Feussner, K; Wright, AD; Dicato, M; Diederich, M,期刊:Journal of natural products, 页码:1120-1120 , 文章类型: Correction,,卷期:2008年71-6]
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- Antioxidant 2-phenylbenzofurans and a coumestan from Lespedeza virgata
[作者:Chen, Y; Wei, XY; Xie, HH; Deng, HZ,期刊:Journal of natural products, 页码:929-932 , 文章类型: Article,,卷期:2008年71-6]
- Two 2-phenylbenzofurans, lespedezavirgatol (1) and lespedezavirgatal (2), and a coumestan, lespedezacoumestan (3), were isolated from the aerial parts of Lespedeza virgata, together with nine known flavonoids. Their stru...
- Mollamides B and C, cyclic hexapeptides from the Indonesian tunicate Didemnum molle
[作者:Donia, MS; Wang, B; Dunbar, DC; Desai, PV; Patny, A; Avery, M; Hamann, MT,期刊:Journal of natural products, 页码:941-945 , 文章类型: Article,,卷期:2008年71-6]
- Two new cyclic hexapeptides, mollamides B (1) and C (2), were isolated from the Indonesian tunicate Didemnum molle along with the known peptide keenamide A (3). The structures were established using ID and 2D NMR experim...
- A C-3 methylated isocembranoid and 10-oxocembranoids from a Formosan soft coral, Sinularia grandilobata
[作者:Ahmed, AF; Tai, SH; Wen, ZH; Su, JH; Wu, YC; Hu, WP; Sheu, JH,期刊:Journal of natural products, 页码:946-951 , 文章类型: Article,,卷期:2008年71-6]
- Five new cembranoids, designated grandilobatins A-E (1-5), were isolated from the soft coral Sinularia grandilobata. Grandilobatin C (3) was found to have a novel skeleton with the C-4 methyl group of the normal cembrano...
- Anticancer activity of isoobtusilactone a from Cinnamomum kotoense: Involvement of apoptosis, cell-cycle dysregulation, mitochondria regulation, and reactive oxygen species
[作者:Chen, CY; Chen, CH; Lo, YC; Wu, BN; Wang, HM; Lo, WL; Yen, CM; Lin, RJ,期刊:Journal of natural products, 页码:933-940 , 文章类型: Article,,卷期:2008年71-6]
- In this study, we investigate the anticancer effect of isoobtusilactone A (IOA), a constituent isolated from the leaves of Cinnamomum kotoense, on human non-small cell lung cancer (NSCLC)A549 cells. IOA was found to indu...
- Ymf 1029A-E, preussomerin analogues from the fresh-water-derived fungus YMF 1.01029
[作者:Dong, JY; Song, HC; Li, JH; Tang, YS; Sun, R; Wang, L; Zhou, YP; Wang, LM; Shen, KZ; Wang, CR; Zhang, KQ,期刊:Journal of natural products, 页码:952-956 , 文章类型: Article,,卷期:2008年71-6]
- Five new preussomerin analogues, ymf 1029A (1), B (2), C (3), D (4), and E (5), were isolated from the liquid cultures of an unidentified freshwater fungus YMF 1.01029, along with four known compounds, preussomerin C (6)...
- Vibrational circular dichroism of africanane and lippifoliane sesquiterpenes from Lippia integrifolia
[作者:Cerda-Garcia-Rojas, CM; Catalan, CAN; Muro, AC; Joseph-Nathan, P,期刊:Journal of natural products, 页码:967-971 , 文章类型: Article,,卷期:2008年71-6]
- The agreement between theoretical and experimental vibrational circular dichroism curves of (4R,9R,10R)-(+)-african-1(5)-ene-2,6-dione (1) and (4R,9S,10R)-lippifoli-1(6)-en-5-one (2), isolated from the widely used plant ...
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