- Down-regulation of deoxycytidine kinase enhances acquired resistance to gemcitabine in pancreatic cancer
[作者:Ohhashi, S; Ohuchida, K; Mizumoto, K; Fujita, H; Egami, T; Yu, J; Toma, H; Sadatomi, S; Nagai, E; Tanaka, M,期刊:Anticancer Research, 页码:2205-2212 , 文章类型: Article,,卷期:2008年28-4B]
- Background: The functional roles of deoxycytidine kinase (dCK) in acquired resistance to gemcitabine. remain unknown in pancreatic cancer. Here, the functional involvement of dCK in gemcitabine-resistance of pancreatic c...
- The growth-promoting action of Individual women's sera on mammary carcinoma CeRls
[作者:Auer, D; Hubalek, M; Fleischer, M; Roessler, J; Daxenbichler, G,期刊:Anticancer Research, 页码:2213-2217 , 文章类型: Article,,卷期:2008年28-4B]
- In vitro studies concerning the growth-stimulating effect of hormones, especially of estradiol and its metabolites, have mainly been performed using pure substances and breast cancer cell lines. In order to take into acc...
- Metastases following biopsy of oral carcinoma in hamsters, and the role of local prebiopsy bleomycin
[作者:Rallis, G; Mourouzis, C; Papakosta, V; Donta, I; Perrea, D; Patsourjs, E; Vairaktaris, E,期刊:Anticancer Research, 页码:2253-2257 , 文章类型: Article,,卷期:2008年28-4B]
- Background: This animal study researches the effect of biopsy on met astasis of oral carcinoma. Materials and Methods: Sixty hamsters developed oral tumors after treatment with 9,10-dimethyl-1,2-benzanthracene and were t...
- Multitarget siRNA inhibition of antiapoptotic genes (XIAP, BCL2, BCL-X-L) in bladder cancer cells
[作者:Kunze, D; Wuttig, D; Fuessel, S; Kraemer, K; Kotzsch, M; Meye, A; Grimm, MO; Hakenberg, OW; Wirth, MP,期刊:Anticancer Research, 页码:2259-2263 , 文章类型: Article,,卷期:2008年28-4B]
- Background: The knockdown of XIAP, BCL2 and BCL-X-L by siRNAs represents a promising treatment option for bladder cancer (BCa) since the overexpression of antiapoptotic genes is often associated with tumor progression an...
- Evidence of a tumour suppressive function of E2F1 gene in human breast cancer
[作者:Worku, D; Jouhra, F; Jiang, GW; Patani, N; Newbold, RF; Mokbel, K,期刊:Anticancer Research, 页码:2135-2139 , 文章类型: Article,,卷期:2008年28-4B]
- Background: The E2F family of transcription factors are key regulators of genes involved in cell cycle progression, cell fate determination, DNA damage repair and apoptosis. E2F1 is unique in that it contributes both to ...
- Abrogation of estrogen receptor signaling augments cytotoxicity of anticancer drugs on CaSki cervical cancer cells
[作者:Heo, MY; Salama, SA; Khatoon, N; Al-Hendy, A; Au, WW,期刊:Anticancer Research, 页码:2181-2187 , 文章类型: Article,,卷期:2008年28-4B]
- Background: We have reported that a gene therapy approach, using a dominant-negative estrogen receptor blocker (DN) gene, can cause cell death in cervical cancer cells in vitro. We investigated the mechanisms for enhance...
- Measurement of serum and tissue des-gamma-earboxypirothrombin in resectable hepatocellular carcinoma
[作者:Xiang, CH; Zhang, W; Inagaki, Y; Zhang, KM; Nakan, Y; Kokudo, N; Sugawara, Y; Dong, JH; Nakata, M; Tang, W,期刊:Anticancer Research, 页码:2219-2224 , 文章类型: Article,,卷期:2008年28-4B]
- Background: The total des-gamma-carboxyprothrombin (DCP) produced in hepatocellular carcinoma (HCC) and the surrounding non-cancer liver tissue was estimated and the correlation between tissue DCP and serum DCP levels wa...
- Arp2/3 overexpression contributed to pathogenesis, growth and invasion of gastric carcinoma
[作者:Zheng, HC; Zheng, YS; Li, XH; Takahashi, H; Hara, T; Masuda, S; Yang, XH; Guan, YF; Takan, Y,期刊:Anticancer Research, 页码:2225-2232 , 文章类型: Article,,卷期:2008年28-4B]
- Background: Tumor metastasis depends on cell adhesion, motility and deformability, resulting front quantitative alterations and rearrangement of actin-related protein (Arp) 2 and 3. The aim of this study was to clarify t...
- Cathepsin B expression in prostate cancer of native Japanese and japanese-American patients: An Immunohistochemical study
[作者:Sinha, AA; Morgan, JL; Betre, K; Wilson, MJ; Le, C; Marks, LS,期刊:Anticancer Research, 页码:2271-2277 , 文章类型: Article,,卷期:2008年28-4B]
- Background: Japanese-American (J-A) men who have immigrated to the U.S.A. and acquired the Western lifestyle usually have more invasive prostate cancer (PCa) than native Japanese (NJ) living in Japan. The specific reason...
- Lipopolysaccharide induces aberrant hypermethylation of Hic-1 in mouse embryonic fibroblasts lacking p53 gene
[作者:Tatemichi, M; Hata, H; Tazawa, H; Nakadate, T,期刊:Anticancer Research, 页码:2101-2108 , 文章类型: Article,,卷期:2008年28-4B]
- Background: The present study asked whether continuous administration with lipopolysaccharide (LPS), a potent inflammatory agent, induces aberrant methylation in the promoter region of tumor suppressor genes and p53 and/...
- Restoration of FGF receptor type 2 enhances radiosensitivity of hormone-refractory human prostate carcinoma PC-3 cells
[作者:Matsubara, A; Teishima, J; Mirkhat, S; Yasumoto, H; Mochizuki, H; Seki, M; Mutaguchi, K; Mckeehan, WL; Usui, T,期刊:Anticancer Research, 页码:2141-2146 , 文章类型: Article,,卷期:2008年28-4B]
- Background: This study was undertaken to investigate the radiosensitizing effects of fibroblast growth factor receptor 2IIIb (FGFR2IIIb) in androgen-independent human prostate carcinoma PC-3 cells devoid of normally resi...
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