- Convenient preparation and characterization of a monoclonal antibody for the N-linked sugar chain of a glycoprotein using a microbial endoglycosidase
[作者:Murakami, D; Shimada, Y; Kamiya, S; Yamazaki, K; Makimura, Y; Ito, K; Minamiura, N; Yamamoto, K,期刊:Archives of Biochemistry and Biophysics , 页码:299-304 , 文章类型: Article,,卷期:2008年477-2]
- We attempted to obtain the monoclonal antibody specific for the N-linked complex-type sialo-oligosaccharide in glycoproteins. We first synthesized a chimeric immunoantigen having an N-linked complex-type of oligosacchari...
- Effect of mutations mimicking phosphorylation on the structure and properties of human 14-3-3 zeta
[作者:Sluchanko, NN; Chernik, IS; Seit-Nebi, AS; Pivovarova, AV; Levitsky, DI; Gusev, NB,期刊:Archives of Biochemistry and Biophysics , 页码:305-312 , 文章类型: Article,,卷期:2008年477-2]
- Effect of mutations mimicking phosphorylation on the structure of human 14-3-3 zeta protein was analyzed by different methods. Mutation S58E increased intrinsic Trp fluorescence and binding of bis-ANS to 14-3-3. At low p...
- Determinants of oligomerization of the bifunctional protein DCoH alpha and the effect on its enzymatic and transcriptional coactivator activities
[作者:Hevel, JM; Pande, P; Viera-Oveson, S; Sudweeks, TJ; Jaffree, LS; Hansen, CM; Ayling, JE,期刊:Archives of Biochemistry and Biophysics , 页码:356-362 , 文章类型: Article,,卷期:2008年477-2]
- DCoH and DCoH alpha are bifunctional proteins that function as 4a-hydroxytetrahydrobiopterin dehydratases and as coactivators of HNF1 alpha-dependent transcription. Although these isoforms share sequence and structural s...
- Fatty acid transport and activation and the expression patterns of genes involved in fatty acid trafficking
[作者:Sandoval, A; Fraisl, P; Arias-Barrau, E; DiRusso, CC; Singer, D; Sealls, W; Black, PN,期刊:Archives of Biochemistry and Biophysics , 页码:363-371 , 文章类型: Article,,卷期:2008年477-2]
- These studies defined the expression patterns of genes involved in fatty acid transport, activation and trafficking using quantitative PCR (qPCR) and established the kinetic constants of fatty acid transport in an effort...
- Mangiferin inhibits cyclooxygenase-2 expression and prostaglandin E-2 production in activated rat microglial cells
[作者:Bhatia, HS; Candelario-Jalil, E; de Oliveira, ACP; Olajide, OA; Martinez-Sanchez, G; Fiebich, BL,期刊:Archives of Biochemistry and Biophysics , 页码:253-258 , 文章类型: Article,,卷期:2008年477-2]
- Mangiferin, a naturally occurring glucosylxanthone, has potent antioxidant and anti-inflammatory properties, as demonstrated in several reports. However, very limited information is available on the effects of this natur...
- Caspase-mediated cleavage of the signal-transducing IL-6 receptor subunit gp130
[作者:Graf, D; Haselow, K; Munks, I; Bode, JG; Haussinger, D,期刊:Archives of Biochemistry and Biophysics , 页码:330-338 , 文章类型: Article,,卷期:2008年477-2]
- The present study characterizes the molecular mechanisms of CD95L-induced inhibition of IL-6 signaling, which is known to mediate hepatoprotective effects in response to various toxins. CD95L-induced caspase activation l...
- Leptin prevents apoptosis of trophoblastic cells by activation of MAPK pathway
[作者:Perez-Perez, A; Maymo, J; Duenas, JL; Goberna, R; Calvo, JC; Varone, C; Sanchez-Margalet, V,期刊:Archives of Biochemistry and Biophysics , 页码:390-395 , 文章类型: Article,,卷期:2008年477-2]
- Leptin (Ob),the peripheral signal produced by the adipocyte to regulate energy metabolism, can also be produced by placenta,where it may work as an autocrine hormone. Recently,we have demonstrated that leptin promotes pr...
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