- Disruption of Mitochondrial Malate-Aspartate Shuttle Activity in Mouse Blastocysts Impairs Viability and Fetal Growth
[作者:Mitchell, M; Cashman, KS; Gardner, DK; Thompson, JG; Lane, M,期刊:Biology of Reproduction, 页码:295-301 , 文章类型: Article,,卷期:2009年80-2]
- The nutrient requirements and metabolic pathways used by the developing embryo transition from predominantly pyruvate during early cleavage stages to glucose at the blastocyst; however, the complexities involved in the r...
- The Histone Deacetylase SIRT1 Controls Male Fertility in Mice Through Regulation of Hypothalamic-Pituitary Gonadotropin Signaling
[作者:Kolthur-Seetharam, U; Teerds, K; de Rooij, DG; Wendling, O; McBurney, M; Sassone-Corsi, P; Davidson, I,期刊:Biology of Reproduction, 页码:384-391 , 文章类型: Article,,卷期:2009年80-2]
- Sirtuins (SIRTs) are class-III NAD-dependent histone deacetylases (HDACs) that regulate various physiological processes. Inactivation of SIRT1 in the mouse leads to male sterility, but the molecular mechanisms responsibl...
- Genetic Loss of Faah Compromises Male Fertility in Mice
[作者:Sun, XF; Wang, HB; Okabe, M; Mackie, K; Kingsley, PJ; Marnett, LJ; Cravatt, BF; Dey, SK,期刊:Biology of Reproduction, 页码:235-242 , 文章类型: Article,,卷期:2009年80-2]
- Marijuana is the most commonly used illicit drug. Although there is some indication that reproductive functions in males are impaired in chronic marijuana users, the genetic evidence and underlying causes remain largely ...
- Expression and Activity of Toll-Like Receptors 1-9 in the Human Term Placenta and Changes Associated with Labor at Term
[作者:Patni, S; Wynen, LP; Seager, AL; Morgan, G; White, JO; Thornton, CA,期刊:Biology of Reproduction, 页码:243-248 , 文章类型: Article,,卷期:2009年80-2]
- Inflammatory processes are involved in the initiation and maintenance of labor, suggesting that toll-like receptor (TLR) activity within gestation-associated tissues, such as the placenta, might contribute to the process...
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