- Conserved amphiphilic feature is essential for periplasmic chaperone HdeA to support acid resistance in enteric bacteria
[作者：Wu, YE; Hong, WZ; Liu, C; Zhang, LQ; Chang, ZY,期刊：Biochemical Journal, 页码：389-397 , 文章类型： Article，,卷期：2008年412-2]
- The extremely acidic environment of the mammalian stomach (pH 1-3) represents a stressful challenge for enteric pathogenic bacteria, including Escherichia coli, Shigella and Brucella. The hdeA (hns-dependent expression A...
- Huntington's disease: from pathology and genetics to potential therapies
[作者：Imarisio, S; Carmichael, J; Korolchuk, V; Chen, CW; Saiki, S; Rose, C; Krishna, G; Davies, JE; Ttofi, E; Underwood, BR; Rubinsztein, DC,期刊：Biochemical Journal, 页码：191-209 , 文章类型： Review，,卷期：2008年412-2]
- Huntington's disease (HD) is a devastating autosomal dominant neurodegenerative disease caused by a CAG trinucleotide repeat expansion encoding an abnormally long polyglutamine tract in the huntingtin protein. Much has b...
- Important role of the LKB1-AMPK pathway in suppressing tumorigenesis in PTEN-deficient mice
[作者：Huang, X; Wullschleger, S; Shpiro, N; McGuire, VA; Sakamoto, K; Woods, YL; McBurnie, W; Fleming, S; Alessi, DR,期刊：Biochemical Journal, 页码：211-221 , 文章类型： Article，,卷期：2008年412-2]
- The LKB1 tumour suppressor phosphorylates and activates AMPK (AMP-activated protein kinase) when cellular energy levels are low, thereby suppressing growth through multiple pathways, including inhibiting the mTORC1 (mamm...
- In vivo quantitative relationship between plastid division proteins FtsZ1 and FtsZ2 and identification of ARC6 and ARC3 in a native FtsZ complex
[作者：McAndrew, RS; Olson, BJSC; Kadirjan-Kalbach, DK; Chi-Ham, CL; Vitha, S; Froehlich, JE; Osteryoung, KW,期刊：Biochemical Journal, 页码：367-378 , 文章类型： Article，,卷期：2008年412-2]
- FtsZ1 and FtsZ2 are phylogenetically distinct homologues of the tubulin-like bacterial cell division protein FtsZ that play major roles in the initiation and progression of plastid division in plant cells. Both proteins ...
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