- Orphan nuclear receptor SHP interacts with and represses hepatocyte nuclear factor-6 (HNF-6) transactivation
[作者:Lee, YS; Kim, DK; Kim, YD; Park, KC; Shong, M; Seong, HA; Ha, HJ; Choi, HS,期刊:Biochemical Journal, 页码:559-569 , 文章类型: Article,,卷期:2008年413-3]
- SHP (small heterodimer partner; NR0B2) is an atypical orphan NR (nuclear receptor) that functions as a transcriptional corepressor by interacting with a diverse set of NRs and transcriptional factors. HNF-6 (hepatocyte n...
- Structure, mechanism and regulation of pyruvate carboxylase
[作者:Jitrapakdee, S; St Maurice, M; Rayment, I; Cleland, WW; Wallace, JC; Attwood, PV,期刊:Biochemical Journal, 页码:369-387 , 文章类型: Review,,卷期:2008年413-3]
- PC (pyruvate carboxylase) is a biotin-containing enzyme that catalyses the HCO3-- and MgATP-dependent carboxylation of pyruvate to form oxaloacetate. This is a very important anaplerotic reaction, replenishing oxaloaceta...
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