- Efficient synthesis of trifluoromethyl and related trisubstituted alkene dipeptide isosteres by palladium-catalyzed carbonylation of amino acid derived allylic carbonates.
[作者:Inokuchi, Eriko;Narumi, Tetsuo;Niida, Ayumu;Kobayashi, Kazuya;Tomita, Kenji;Oishi, Shinya;Ohno, Hiroaki;Fujii, Nobutaka;,期刊:Journal of Organic Chemistry, 页码:3942-3945 , 文章类型: 研究论文,,卷期:2008年73-10]
- A novel stereoselective synthetic approach to (Z)-trifluoromethylalkene dipeptide isosteres (CF3-ADIs) is described. Starting from readily available N-Boc-L-phenylalanine, Phe-Gly type CF3-ADIs were obtained through pal...
- New Telluride-Mediated Elimination for Novel Synthesis of 2',3'-Didehydro-2',3'-dideoxynucleosides.
[作者:Sheng, Jia;Hassan, Abdalla E. A.;Huang, Zhen;,期刊:Journal of Organic Chemistry, 页码:3725-3729 , 文章类型: 研究论文,,卷期:2008年73-10]
- Several 2',3'-dideoxynucleosides (ddNs) and 2',3'-didehydro-2',3'-dideoxynucleosides (d4Ns) are FDA-approved anti-HIV drugs. Via conveniently synthesized 2,2'-anhydronucleosides, we have developed a novel synthesis of d...
- Phorbasides A-E, Cytotoxic Chlorocyclopropane Macrolide Glycosides from the Marine Sponge Phorbas sp. CD Determination of C-Methyl Sugar Configurations.
[作者:MacMillan, John B.;Guang, Xiong-Zhou;Skepper, Colin K.;Molinski, Tadeusz F.;,期刊:Journal of Organic Chemistry, 页码:3699-3706 , 文章类型: 研究论文,,卷期:2008年73-10]
- Five new cytotoxic macrolide glycosides phorbasides A (e.g. I)-E, each possessing a macrolide ring appended to a rare ene-yne-trans-2-chlorocyclopropane, were isolated from the same Western Australian sponge (Phorbas sp....
- Cation-induced p-stacking.
[作者:Bosch, Eric;Barnes, Charles L.;Brennan, Nathan L.;Eakins, Galen L.;Breyfogle, Bryan E.;,期刊:Journal of Organic Chemistry, 页码:3931-3934 , 文章类型: 研究论文,,卷期:2008年73-10]
- The design and synthesis of a new dipyridyl ligand with appended trifluoromethanesulfonate to a soln. of I, the phenanthryl protons shift upfield in the 1H NMR spectrum, suggesting that the phenanthrenes p-stack on coord...
- Unsymmetric Pyrrole, Thiophene, and Furan-Conjugated Comonomers Prepared Using Azomethine Connections: Potential New Monomers for Alternating Homocoupled Products.
[作者:Dufresne, Stephane;Skene, W. G.;,期刊:Journal of Organic Chemistry, 页码:3859-3866 , 文章类型: 研究论文,,卷期:2008年73-10]
- Unsym. comonomers consisting of thiophene, pyrrole, and furan heterocycles were prepd. using azomethine bonds. Photophys. investigation of the novel p-donor-donor-donor segmented compds. revealed that their singlet exci...
- Titanocene(III) Chloride Mediated Radical-Induced Addition to Baylis-Hillman Adducts: Synthesis of (E)- and (Z)-Trisubstituted Alkenes and a-Methylene/Arylidene d-Lactones.
[作者:Mandal, Samir K.;Paira, Moumita;Roy, Subhas C.;,期刊:Journal of Organic Chemistry, 页码:3823-3827 , 文章类型: 研究论文,,卷期:2008年73-10]
- Baylis-Hillman adducts H2C:CR1CHR2OAc (R1 = CO2Me, R2 = H, Ph, 4-ClC6H4, 4-MeC6H4; R1 = CN, R2 = 4-MeC6H4) (I) underwent smooth radical-induced condensation with activated halides R3X (R3 = H2C:CHCH2, PhCH2, 4-ClC6H4, 4-...
- A Cross-Metathesis Route to the 5-F2-Isoprostanes.
[作者:Pandya, Bhaumik A.;Snapper, Marc L.;,期刊:Journal of Organic Chemistry, 页码:3754-3758 , 文章类型: 研究论文,,卷期:2008年73-10]
- A library of eight 5-F2-isoprostanes, e.g. I, was prepd. through a ring-opening metathesis/cross-metathesis protocol between functionalized bicyclo[3.2.0]heptenes, ethylene, and a,b-unsatd. ketones. This sequence provid...
- Efficient Synthesis of cis- and trans-3,4-Dihydroxy-3,4-dihydromollugin.
[作者:Mudiganti, Naga Venkata Sastry;Claessens, Sven;Habonimana, Pascal;De Kimpe, Norbert;,期刊:Journal of Organic Chemistry, 页码:3867-3874 , 文章类型: 研究论文,,卷期:2008年73-10]
- An efficient synthesis of naturally occurring compds. isolated from Pentas longiflora, cis-3,4-dihydroxy-3,4-dihydromollugin (I), and trans-3,4-dihydroxy-3,4-dihydromollugin (II) is described. The O-protected mollugins ...
- A Novel One-Pot Pseudo-Five-Component Synthesis of 4,5,6,7-Tetrahydro-1H-1,4-diazepine-5-carboxamide Derivatives.
[作者:Shaabani, Ahmad;Maleki, Ali;Mofakham, Hamid;Moghimi-Rad, Jafar;,期刊:Journal of Organic Chemistry, 页码:3925-3927 , 文章类型: 研究论文,,卷期:2008年73-10]
- (Heterocyclic Compounds (More Than One Hetero Atom)) Section A novel one-pot pseudo-five-component synthesis of 4,5,6,7-tetrahydro-1H-1,4-diazepine-5-carboxamide derivs., e.g., I, starting from simple and readily availab...
- A Tandem Approach to Isoquinolines from 2-Azido-3-arylacrylates and a-Diazocarbonyl Compounds.
[作者:Yang, Yun-Yun;Shou, Wang-Ge;Chen, Zheng-Bo;Hong, Deng;Wang, Yan-Guang;,期刊:Journal of Organic Chemistry, 页码:3928-3930 , 文章类型: 研究论文,,卷期:2008年73-10]
- 2-Azido-3-arylacrylates react with a-diazocarbonyl compds. and triphenylphosphine to furnish isoquinolines in 60-92% yields. The tandem process involves a Wolff rearrangement, an aza-Wittig reaction, and an electrocycli...
|