- Hypoxic preconditioning results in increased motility and improved therapeutic potential of human mesenchymal stem cells
[作者:Rosova, I; Dao, M; Capoccia, B; Link, D; Nolta, JA,期刊:Stem Cells, 页码:2173-2182 , 文章类型: Article,,卷期:2008年26-8]
- Alesenchymal stem cells (MSC) are adult multipotent cells found in bone marrow, adipose tissue, and other adult tissues. MSC have been shown to improve regeneration of injured tissues in vivo, but the mechanisms remain u...
- Tcf3 functions as a steady-state limiter of transcriptional programs of mouse embryonic stem cell self-renewal
[作者:Yi, F; Pereira, L; Merrill, BJ,期刊:Stem Cells, 页码:1951-1960 , 文章类型: Article,,卷期:2008年26-8]
- Elucidating the underlying transcriptional control of pluripotent cells is necessary for the development of new methods (of inducing and maintaining pluripotent cells in vitro. Three transcription factors, Nanog, Oct4, a...
- Calcium handling in human embryonic stem cell-derived cardiomyocytes
[作者:Satin, J; Itzhaki, I; Rapoport, S; Schroder, EA; Izu, L; Arbel, G; Beyar, R; Balke, CW; Schiller, J; Gepstein, L,期刊:Stem Cells, 页码:1961-1972 , 文章类型: Article,,卷期:2008年26-8]
- The objective of the current study was to characterize calcium handling in developing human embryonic stem cell-derived cardiomyocytes (hESC-CMs). To this end, real-time polymerase chain reaction (PCR), immunocytochemist...
- Tenascin-R promotes neuronal differentiation of embryonic stem cells and recruitment of host-derived neural precursor cells after excitotoxic lesion of the mouse striatum
[作者:Hargus, G; Cui, YF; Schmid, JS; Xu, JC; Glatzel, M; Schachner, M; Bernreuther, C,期刊:Stem Cells, 页码:1973-1984 , 文章类型: Article,,卷期:2008年26-8]
- Loss of GABAergic projection neurons under excitotoxic conditions in the striatum is associated with a disturbance of motor and cognitive functions as seen, for instance, in Huntington's disease. Since current treatments...
- Improved efficiency and pace of generating induced pluripotent stem cells from human adult and fetal fibroblasts
[作者:Mali, P; Ye, ZH; Hommond, HH; Yu, XB; Lin, J; Chen, GB; Zou, JZ; Cheng, LZ,期刊:Stem Cells, 页码:1998-2005 , 文章类型: Article,,卷期:2008年26-8]
- It was reported recently that human fibroblasts can be reprogrammed into a pluripotent state that resembles that of human embryonic stem (hES) cells. This was achieved by ectopic expression of four genes followed by cult...
- Characterization of a novel ubiquitin-conjugating enzyme that regulates beta 1,4-galactosyltransferase-1 in embryonic stem cells
[作者:Wassler, MJ; Shur, BD; Zhou, WX; Geng, YJ,期刊:Stem Cells, 页码:2006-2018 , 文章类型: Article,,卷期:2008年26-8]
- In this study we identified a novel galactosyltransferase 1-associating protein (GTAP) by cDNA cloning from a murine embryonic cDNA library using the two-hybrid yeast system. GTAP is expressed in early embryonic tissues,...
- T-cell factor 3 regulates embryonic stem cell pluripotency and self-renewal by the transcriptional control of multiple lineage pathways
[作者:Tam, WL; Lim, CY; Han, JY; Zhang, JQ; Ang, YS; Ng, HH; Yang, H; Lim, B,期刊:Stem Cells, 页码:2019-2031 , 文章类型: Article,,卷期:2008年26-8]
- The Wnt signaling pathway is necessary both for maintaining undifferentiated stem cells and for directing their differentiation. In mouse embryonic stem cells (ESCs), Wnt signaling preferentially maintains "stemness" und...
- Isolation and transcriptional profiling of purified hepatic cells derived from human embryonic stem cells
[作者:Chiao, E; Elazar, M; Xing, Y; Xiong, AM; Kmet, M; Millan, MT; Glenn, JS; Wong, WH; Baker, J,期刊:Stem Cells, 页码:2032-2041 , 文章类型: Article,,卷期:2008年26-8]
- The differentiation of human embryonic stem cells (hESCs) into functional hepatocytes provides a powerful in vitro model system for studying the molecular mechanisms governing liver development. Furthermore, a well-chara...
- Hematopoietic stem cells regulate mesenchymal stromal cell induction into osteoblasts thereby participating in the formation of the stem cell niche
[作者:Jung, YG; Song, JH; Shiozawa, Y; Wang, JC; Wang, Z; Williams, B; Havens, A; Schneider, A; Ge, CX; Franceschi, RT; McCauley, LK; Krebsbach, PH; Taichman, RS,期刊:Stem Cells, 页码:2042-2051 , 文章类型: Article,,卷期:2008年26-8]
- Crosstalk between hematopoietic stem cells (HSCs) and the cells comprising the niche is critical for maintaining stem cell activities. Yet little evidence supports the concept that HSCs regulate development of the niche....
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