- Induction of proliferation and monocytic differentiation of human CD34(+) cells by CD137 ligand signaling
[作者:Jiang, D; Yue, PSE; Drenkard, D; Schwarz, H,期刊:Stem Cells, 页码:2372-2381 , 文章类型: Article,,卷期:2008年26-9]
- CD137 is a member of the tumor necrosis factor receptor family and is involved in the regulation of activation, proliferation, differentiation, and cell death of leukocytes. Bidirectional signaling exists for the CD137 r...
- A reservoir of brown adipocyte progenitors in human skeletal muscle
[作者:Crisan, M; Casteilla, L; Lehr, L; Carmona, M; Paoloni-Giacobino, A; Yap, S; Sun, B; Leger, B; Logar, A; Penicaud, L; Schrauwen, P; Cameron-Smith, D; Russell, AP; Peault, B; Giacobino, JP,期刊:Stem Cells, 页码:2425-2433 , 文章类型: Article,,卷期:2008年26-9]
- Brown adipose tissue uncoupling protein-1 (UCP1) plays a major role in the control of energy balance in rodents. It has long been thought, however, that there is no physiologically relevant UCP1 expression in adult human...
- Adult germ line stem cells as a source of functional neurons and glia
[作者:Glaser, T; Opitz, T; Kischlat, T; Konang, R; Sasse, P; Fleischmann, BK; Engel, W; Nayernia, K; Brustle, O,期刊:Stem Cells, 页码:2434-2443 , 文章类型: Article,,卷期:2008年26-9]
- The derivation of autologous pluripotent cells has become a central goal in translational stem cell research. Although somatic cell nuclear transfer and transcription factor-based reprogramming enable the generation of p...
- Human embryonic stem cells have enhanced repair of multiple forms of DNA damage
[作者:Maynard, S; Swistowska, AM; Lee, JW; Liu, Y; Liu, ST; Da Cruz, AB; Rao, M; de Souza-Pinto, NC; Zeng, XM; Bohr, VA,期刊:Stem Cells, 页码:2266-2274 , 文章类型: Article,,卷期:2008年26-9]
- Embryonic stem cells need to maintain genomic integrity so that they can retain the ability to differentiate into multiple cell types without propagating DNA errors. Previous studies have suggested that mechanisms of gen...
- The myelopoietic supportive capacity of mesenchymal stromal cells is uncoupled from multipotency and is influenced by lineage determination and interference with glycosylation
[作者:Morad, V; Pevsner-Fischer, M; Barnees, S; Samokovlisky, A; Rousso-Noori, L; Rosenfeld, R; Zipori, D,期刊:Stem Cells, 页码:2275-2286 , 文章类型: Article,,卷期:2008年26-9]
- Cultured bone marrow stromal cells create an in vitro milieu supportive of long-term hemopoiesis and serve as a source for multipotent mesenchymal progenitor cells defined by their ability to differentiate into a variety...
- Noninvasive and quantitative monitoring of adult neuronal stem cell migration in mouse brain using bioluminescence imaging
[作者:Reumers, V; Deroose, CM; Krylyshkina, O; Nuyts, J; Geraerts, M; Mortelmans, L; Gijsbers, R; Van den Haute, C; Debyser, Z; Baekelandt, V,期刊:Stem Cells, 页码:2382-2390 , 文章类型: Article,,卷期:2008年26-9]
- It is now generally accepted that continuous neurogenesis occurs in the adult mammalian brain, including that of humans. Modulation of adult neurogenesis can provide therapeutic benefits for various brain disorders, incl...
- SJL dystrophic mice express a significant amount of human muscle proteins following systemic delivery of human adipose-derived stromal cells without immunosuppression
[作者:Vieira, NM; Bueno, CR; Brandalise, V; Moraes, LV; Zucconi, E; Secco, M; Suzuki, MF; Camargo, MM; Bartolini, P; Brum, PC; Vainzof, M; Zatz, M,期刊:Stem Cells, 页码:2391-2398 , 文章类型: Article,,卷期:2008年26-9]
- Limb-girdle muscular dystrophies (LGMDs) are a heterogeneous group of disorders characterized by progressive degeneration of skeletal muscle caused by the absence of or defective muscular proteins. The murine model for l...
- Control of human embryonic stem cell colony and aggregate size heterogeneity influences differentiation trajectories
[作者:Bauwens, CL; Peerani, R; Niebruegge, S; Woodhouse, KA; Kumacheva, E; Husain, M; Zandstra, PW,期刊:Stem Cells, 页码:2300-2310 , 文章类型: Article,,卷期:2008年26-9]
- To better understand endogenous parameters that influence pluripotent cell differentiation we used human embryonic stem cells (hESCs) as a model system. We demonstrate that differentiation trajectories in aggregate (embr...
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